Browse our anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Antibodies

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anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies (PRPF31)
On www.antibodies-online.com are 70 PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Antibodies from 14 different suppliers available. Additionally we are shipping PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (8) and many more products for this protein. A total of 85 PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) products are currently listed.
Synonyms:
1500019O16Rik, 2810404O06Rik, AW554706, DDBDRAFT_0219465, DDBDRAFT_0304959, DDB_0219465, DDB_0304959, NY-BR-99, prp31, PRPF31, rp11, SNRNP61, zgc:66177
list all antibodies Gene Name GeneID UniProt
PRPF31 26121 Q8WWY3
PRPF31 292536  
PRPF31 68988 Q8CCF0

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All available anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies

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Top referenced anti-PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies

  1. Dog (Canine) Polyclonal PRPF31 Primary Antibody for EIA, WB - ABIN498020 : Makarova, Makarov, Liu, Vornlocher, Lührmann: Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing. in The EMBO journal 2002 (PubMed)

  2. Human Polyclonal PRPF31 Primary Antibody for ELISA, WB - ABIN565227 : Nag, Steitz: Tri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicing. in RNA biology 2012 (PubMed)

  3. Human Polyclonal PRPF31 Primary Antibody for ELISA, WB - ABIN188685 : Yuan, Kawada, Havlioglu, Tang, Wu: Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 (PubMed)

  4. Human Monoclonal PRPF31 Primary Antibody for ELISA, WB - ABIN949177 : Adler, McCleland, Yee, Yaylaoglu, Hussain, Cosino, Quinones, Modrusan, Seshagiri, Torres, Chopra, Haley, Zhang, Blackwood, Singh, Junttila, Stephan, Liu, Pau, Fearon, Jiang, Firestein: An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. in Genes & development 2014 (PubMed)

More Antibodies against PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Interaction Partners

Human PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. We show that PRP31, a component of U4 snRNP (show LSM2 Antibodies), is modified with K63-linked ubiquitin chains by the PRP19 (show PRPF19 Antibodies) complex and deubiquitinated by USP15 (show USP15 Antibodies) and its substrate targeting factor SART3 (show SART3 Antibodies). USP15SART3 makes a complex with USP4 (show USP4 Antibodies) and this ternary complex serves as a platform to deubiquitinate PRP31 and PRP3 (show CLCA4 Antibodies)

  2. We also demonstrate that across the human genome, the presence of MSR1 (show MSR1 Antibodies) repeats in the promoters or first introns of genes is associated with greater population variability in gene expression indicating that copy number variation of MSR1s is a generic controller of gene expression and promises to provide new insights into our understanding of gene expression regulation

  3. In view of the high genetic heterogeneity of PRPF31 mutations, the screening must include the entire gene, as well as CNV assays, to detect large rearrangements.

  4. This study identified host factor PRPF31 as a cellular factor involved in Hepatitis B virus covalently closed circular DNA (cccDNA)formation. PRPF31 is recruited to cccDNA. Chromatin immunoprecipitation and immunoprecipitation assays revealed an association between PRPF31 and cccDNA.

  5. Variant haploinsufficiency and phenotypic non-penetrance in PRPF31-associated retinitis pigmentosa has been described.

  6. This is the first Swedish report of the clinical phenotype associated with a mutation in the PRPF31 (p.IVS6+1G>T) gene.

  7. The small nuclear ribonucleoprotein U4 core-domain structure has now been re-refined. The U4 Sm site-sequence AAUUUUU has been shown to bind to the seven Sm proteins SmF-SmE-SmG-SmD3-SmB-SmD1-SmD2 in an identical manner as the U1 Sm-site sequence AAUUUGU, except in SmD1 where the bound U replaces G.

  8. As PRPF31 mutations cause retinitis pigmentosa by haploinsufficiency, this is a good candidate for adeno (show ADORA2A Antibodies)-associated virus (AAV)-based gene augmentation therapy.

  9. A PRPF31 mutation was identified to be responsible for adRP (show PLIN2 Antibodies) in a large Chinese family. Our findings expand the mutation spectrum of RP in the Chinese population.

  10. A mutation in PRPF31 is hypostatic to a trait acting on CNOT3 (show CNOT3 Antibodies), with the RP11 phenotype only being observed when there is homozygous (recessive) inheritance of the higher expressivity CNOT3 (show CNOT3 Antibodies) ("symptomatic" or risk) allele.

Mouse (Murine) PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. The mouse retinal pigment epithelium (RPE (show RPE Antibodies))is the primary cell affected by mutations in the RNA splicing factors (PRPF3 (show PRPF3 Antibodies), PRPF8 (show PRPF8 Antibodies), and PRPF31), and these changes occur at an early age.

  2. found that PRP31 and PRPC8 (show PRPF8 Antibodies) as well as snRNAs are highly expressed in retinal cells

  3. CTNNBL1 (show CTNNBL1 Antibodies) is a novel nuclear localization sequence-binding protein (show NSR1 Antibodies) that recognizes RNA-splicing factors CDC5L (show CDC5L Antibodies) and Prp31

  4. The finding of similar degenerative changes in RPE (show RPE Antibodies) cells of all three mouse models suggests that the retinal pigment epithelium may be the primary cell type affected in the RNA splicing factor (show SLU7 Antibodies) forms of retinitis pigmentosa.

  5. Our results demonstrate that mutations in PRPF31 gene affect rhodopsin (show RHO Antibodies) (RHO) pre-mRNA splicing and reveal a link between PRPF31 and RHO, two major genes in autosomal dominant retinitis pigmentosa.

  6. Our results indicate that PRPF31 mutations lead to defective pre-mRNA splicing of photoreceptor-specific genes and that the ubiquitously expressed adRP (show PLIN2 Antibodies) gene, PRPF31, is critical for pre-mRNA splicing of a subset of photoreceptor genes.

  7. The results imply that Prpf31 is necessary for survival, and there is no compensation mechanism in mouse for the lack of this splicing factor (show SLU7 Antibodies)

PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Antigen Profile

Antigen Summary

This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Alternative names and synonyms associated with PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31)

  • PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) (PRPF31) antibody
  • pre-mRNA processing factor 31 (prpf31) antibody
  • PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) (PrpF31) antibody
  • PRP31 pre-mRNA processing factor 31 homolog (PRPF31) antibody
  • pre-mRNA processing factor 31 (PRPF31) antibody
  • pre-mRNA processing factor 31 (Prpf31) antibody
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (Prpf31) antibody
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (prpf31) antibody
  • 1500019O16Rik antibody
  • 2810404O06Rik antibody
  • AW554706 antibody
  • DDBDRAFT_0219465 antibody
  • DDBDRAFT_0304959 antibody
  • DDB_0219465 antibody
  • DDB_0304959 antibody
  • NY-BR-99 antibody
  • prp31 antibody
  • PRPF31 antibody
  • rp11 antibody
  • SNRNP61 antibody
  • zgc:66177 antibody

Protein level used designations for PRPF31

pre-mRNA processing factor 31 homolog , PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) , PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) , PRP31 pre-mRNA processing factor 31 homolog , u4/U6 small nuclear ribonucleoprotein Prp31-like , U4/U6 small nuclear ribonucleoprotein Prp31 , U4/U6 snRNP 61 kDa protein , hPrp31 , pre-mRNA-processing factor 31 , protein 61K , serologically defined breast cancer antigen NY-BR-99 , pre-mRNA processing factor 31-like protein

GENE ID SPECIES
456278 Pan troglodytes
8627218 Dictyostelium discoideum AX4
9832603 Ostreococcus tauri
100019854 Monodelphis domestica
100049878 Equus caballus
100137336 Papio anubis
100455616 Pongo abelii
26121 Homo sapiens
292536 Rattus norvegicus
495301 Xenopus laevis
476389 Canis lupus familiaris
513577 Bos taurus
68988 Mus musculus
393476 Danio rerio
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