Browse our PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (PRPF31)

Full name:
PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (PRPF31)
On www.antibodies-online.com are 8 PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Proteins from 4 different suppliers available. Additionally we are shipping PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies (70) and many more products for this protein. A total of 85 PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) products are currently listed.
Synonyms:
1500019O16Rik, 2810404O06Rik, AW554706, DDBDRAFT_0219465, DDBDRAFT_0304959, DDB_0219465, DDB_0304959, NY-BR-99, prp31, PRPF31, rp11, SNRNP61, zgc:66177
list all proteins Gene Name GeneID UniProt
PRPF31 26121 Q8WWY3
Rat PRPF31 PRPF31 292536  
PRPF31 68988 Q8CCF0

Show all synonyms

PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (PRPF31) by Origin

Select your origin of interest

More Proteins for PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Interaction Partners

Human PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. We also demonstrate that across the human genome, the presence of MSR1 (show MSR1 Proteins) repeats in the promoters or first introns of genes is associated with greater population variability in gene expression indicating that copy number variation of MSR1s is a generic controller of gene expression and promises to provide new insights into our understanding of gene expression regulation

  2. In view of the high genetic heterogeneity of PRPF31 mutations, the screening must include the entire gene, as well as CNV assays, to detect large rearrangements.

  3. This study identified host factor PRPF31 as a cellular factor involved in Hepatitis B virus covalently closed circular DNA (cccDNA)formation. PRPF31 is recruited to cccDNA. Chromatin immunoprecipitation and immunoprecipitation assays revealed an association between PRPF31 and cccDNA.

  4. Variant haploinsufficiency and phenotypic non-penetrance in PRPF31-associated retinitis pigmentosa has been described.

  5. This is the first Swedish report of the clinical phenotype associated with a mutation in the PRPF31 (p.IVS6+1G>T) gene.

  6. The small nuclear ribonucleoprotein U4 core-domain structure has now been re-refined. The U4 Sm site-sequence AAUUUUU has been shown to bind to the seven Sm proteins SmF-SmE-SmG-SmD3-SmB-SmD1-SmD2 in an identical manner as the U1 Sm-site sequence AAUUUGU, except in SmD1 where the bound U replaces G.

  7. As PRPF31 mutations cause retinitis pigmentosa by haploinsufficiency, this is a good candidate for adeno (show ADORA2A Proteins)-associated virus (AAV)-based gene augmentation therapy.

  8. A PRPF31 mutation was identified to be responsible for adRP (show PLIN2 Proteins) in a large Chinese family. Our findings expand the mutation spectrum of RP in the Chinese population.

  9. A mutation in PRPF31 is hypostatic to a trait acting on CNOT3 (show CNOT3 Proteins), with the RP11 phenotype only being observed when there is homozygous (recessive) inheritance of the higher expressivity CNOT3 (show CNOT3 Proteins) ("symptomatic" or risk) allele.

  10. identification of the novel "A" insertion mutation in exon9 at chr19:54629961-54629961 in PRPF31 can provide further genetic evidence for clinical test for adRP (show PLIN2 Proteins) and JMD.

Mouse (Murine) PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. The mouse retinal pigment epithelium (RPE (show RPE Proteins))is the primary cell affected by mutations in the RNA splicing factors (PRPF3 (show PRPF3 Proteins), PRPF8, and PRPF31), and these changes occur at an early age.

  2. found that PRP31 and PRPC8 as well as snRNAs are highly expressed in retinal cells

  3. CTNNBL1 (show CTNNBL1 Proteins) is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L (show CDC5L Proteins) and Prp31

  4. The finding of similar degenerative changes in RPE (show RPE Proteins) cells of all three mouse models suggests that the retinal pigment epithelium may be the primary cell type affected in the RNA splicing factor (show SLU7 Proteins) forms of retinitis pigmentosa.

  5. Our results demonstrate that mutations in PRPF31 gene affect rhodopsin (RHO) pre-mRNA splicing and reveal a link between PRPF31 and RHO, two major genes in autosomal dominant retinitis pigmentosa.

  6. Our results indicate that PRPF31 mutations lead to defective pre-mRNA splicing of photoreceptor-specific genes and that the ubiquitously expressed adRP (show PLIN2 Proteins) gene, PRPF31, is critical for pre-mRNA splicing of a subset of photoreceptor genes.

  7. The results imply that Prpf31 is necessary for survival, and there is no compensation mechanism in mouse for the lack of this splicing factor (show SLU7 Proteins)

PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Protein Profile

Protein Summary

This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Alternative names and synonyms associated with PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31)

  • PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) (PRPF31)
  • pre-mRNA processing factor 31 (prpf31)
  • PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) (PrpF31)
  • PRP31 pre-mRNA processing factor 31 homolog (PRPF31)
  • pre-mRNA processing factor 31 (PRPF31)
  • pre-mRNA processing factor 31 (Prpf31)
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (Prpf31)
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (prpf31)
  • 1500019O16Rik protein
  • 2810404O06Rik protein
  • AW554706 protein
  • DDBDRAFT_0219465 protein
  • DDBDRAFT_0304959 protein
  • DDB_0219465 protein
  • DDB_0304959 protein
  • NY-BR-99 protein
  • prp31 protein
  • PRPF31 protein
  • rp11 protein
  • SNRNP61 protein
  • zgc:66177 protein

Protein level used designations for PRPF31

pre-mRNA processing factor 31 homolog , PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) , PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) , PRP31 pre-mRNA processing factor 31 homolog , u4/U6 small nuclear ribonucleoprotein Prp31-like , U4/U6 small nuclear ribonucleoprotein Prp31 , U4/U6 snRNP 61 kDa protein , hPrp31 , pre-mRNA-processing factor 31 , protein 61K , serologically defined breast cancer antigen NY-BR-99 , pre-mRNA processing factor 31-like protein

GENE ID SPECIES
456278 Pan troglodytes
8627218 Dictyostelium discoideum AX4
9832603 Ostreococcus tauri
100019854 Monodelphis domestica
100049878 Equus caballus
100137336 Papio anubis
100455616 Pongo abelii
26121 Homo sapiens
292536 Rattus norvegicus
495301 Xenopus laevis
476389 Canis lupus familiaris
513577 Bos taurus
68988 Mus musculus
393476 Danio rerio
Selected quality suppliers for PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (PRPF31)
Did you look for something else?