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Human ATP2B1 ELISA Kit for Sandwich ELISA - ABIN811211
Wu, Guo, Bi, Wang, Du: UVB irradiation-induced dysregulation of plasma membrane calcium ATPase1 and intracellular calcium homeostasis in human lens epithelial cells. in Molecular and cellular biochemistry 2013
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Adding pure bovine MMP-2 (show MMP2 ELISA Kits) to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase (show CA-P60A ELISA Kits) activity, but the pretreatment with TIMP-2 (show TIMP2 ELISA Kits) inhibits the increase in the enzyme activity
To demonstrate the subcellular localization and regulation of bovine sperm PMCA, cell fractionation, enzyme activity determination and Western blotting studies of PMCA in spermatozoa removed from the cauda epididymidis of bull, was performed.
Crossover analysis and stratified analysis indicated that BMI has a major effect on the development of hypertension, while ATP2B1 variants have a minor effect
Excessive sodium intake significantly modified the risk of developing Hypertension associated with ATP2B1 rs17249754 genetic trait. Homozygote carriers may be at higher risk of hypertension, when they consume excessive sodium intake.
Data show that plasma membrane Ca(2+)-ATPase (show ATP2B2 ELISA Kits) (PMCA) was associated with tubulin (show TUBB ELISA Kits) in normotensive and hypertensive erythrocytes.
rs11105378 near ATP2B1 was associated with increased systolic and diastolic blood pressure in a Chinese population.
ATP2B1 rs12817819 A allele is associated with increased risk for drug resistant hypertension.
While PMCA1b has a housekeeping function in colon cancer cells, PMCA4b (show ATP2B4 ELISA Kits) participates in the reorganization of the calcium signaling machinery during cell differentiation.
Report that ATP2B1 rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women.
An increase of phosphatidylcholine (show SGMS2 ELISA Kits)/detergent molar ratio leads to a biphasic behavior of the PMCA Ca2+-ATPase activity, whose maximum depends on phosphatidylcholine (show SGMS2 ELISA Kits) characteristics.
The present study confirmed the significant association of ATP2B1 rs17249754 with risk of hypertension among Chinese children.
The downregulation of PMCA1 and the disruption of calcium homeostasis may play important roles in UVB-induced HLE (show ELANE ELISA Kits) B-3 cell apoptosis.
Purified plasma membrane Ca2+ ATPase was able to hydrolyze ATP at a very low rate in the absence of Ca2 (show CA2 ELISA Kits)+.
results suggest that the activating mechanism of ethanol may involve opening an autoinhibitory domain located close to the calmodulin (show CALM PLURAL_@27096@) binding domain
ceramide activates plasma membrane Ca2+-ATPase from kidney-promixal tubule cells with protein kinase A as an intermediate
Deletion of the Pmca1 in the intestine is associated with reduced growth and bone mineralization, and a failure to up-regulate calcium absorption in response to 1alpha,25(OH)2D3.
decreased ATP2B1 gene expression is associated with impaired endothelial NOS (show NOS3 ELISA Kits) activity and nitric oxide production, and the ATP2B1 gene plays a crucial role in the regulation of blood pressure
ATP2B1 is the causative gene in the blood pressure-associated 12q21 locus; ATP2B1 expression in the vessel influences blood pressure
ATP2B1 plays important roles in the regulation of blood pressure through alteration of calcium handling and vasoconstriction in vascular smooth muscle cells.
Cav1.4alpha1 (show CACNA1F ELISA Kits) is required for proper targeting of the presynaptic PMCA1 complex in retinal photoreceptors.
the decapacitation mechanism of the SVA might target membrane sphingolipid SPM (show NPC1 ELISA Kits) and regulate PMCA activity to lower [Ca(2 (show CA2 ELISA Kits)+)](i), thereby decreasing the [cAMP](i) level and preventing sperm pre-capacitation.
Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger (show SLC8A1 ELISA Kits) expression in distal convoluted tubule cells mediate calcium efflux.
Mouse photoreceptors, cone bipolar cells and horizontal cells, which respond to light with a graded polarization, express isoform PMCA1
results are consistent with an essential housekeeping or developmental function for plasma membrane Ca2+-ATPase (PMCA)1
Data indicate that plasma membrane Ca(2 (show CA2 ELISA Kits)+)-ATPases 1 and 4, in addition to SERCA2 (show ATP2A2 ELISA Kits) and NCX (show SLC8A1 ELISA Kits), play a significant role in both excitation-contraction coupling and calcium homeostasis in bladder smooth muscle.
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified.
plasma membrane calcium ATPase 1
, plasma membrane calcium-transporting ATPase 1
, plasma membrane calcium pump
, ATPase, Ca++ transporting, plasma membrane 1
, plasma membrane calcium-transporting ATPase 1-like
, plasma membrane calcium ATPase
, plasma membrane Ca2+ pump (PMCA1b)
, Ca2+/Mg2+ ATPase