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Human C2orf60 Protein expressed in Escherichia coli (E. coli) - ABIN1098482
Kato, Araiso, Noma, Nagao, Suzuki, Ishitani, Nureki: Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification. in Nucleic acids research 2011
Show all 2 references for 1098482
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes (By similarity).
jmjC domain-containing protein C2orf60
, jmjC domain-containing protein C2orf60-like
, tRNA wybutosine-synthesizing protein 5
, tRNA yW-synthesizing enzyme 5
, uncharacterized protein LOC301419
, jmjC domain-containing protein C2orf60 homolog