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analysis of dietary rescue of fumble in a Drosophila model for pantothenate kinase-associated neurodegeneration
Only mitochondria-targeted Fbl or human PanK2 (show PANK2 ELISA Kits) was able to rescue fbl mutation.
Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions.
FBL overexpression contributes to tumorigenesis and is associated with poor survival in patients with breast cancer.
NS1 (show PTPN11 ELISA Kits) protein of the human H3N2 virus interacts primarily via the C-terminal NLS2/NoLS and to a minor extent via the N-terminal NLS1 with the main nucleolar proteins, nucleolin (show NCL ELISA Kits), B23 (show NPM1 ELISA Kits) and fibrillarin.
p32 (show C1QBP ELISA Kits) is a new rRNA maturation factor involved in the remodeling from pre-90S particles to pre-40S and pre-60S particles that requires the exchange of FBL for Nop52 (show RRP1 ELISA Kits).
Increased levels of exogenous BRAG2 in nucleoli result in redistribution of FBL to the nucleolar periphery.
Our data suggest that fibrillarin would play a critical role in the maintenance of nuclear shape and cellular growth.
Evidence that BIG1 (show CNTN3 ELISA Kits) and nucleolin (show NCL ELISA Kits), but not fibrillarin, can be present with p62 (show GTF2H1 ELISA Kits) at the nuclear envelope confirms the presence of BIG1 (show CNTN3 ELISA Kits) and nucleolin (show NCL ELISA Kits) in dynamic molecular complexes that change in composition while moving through nuclei
Data demonstrate that fibrillarin and Nop56 (show NOP56 ELISA Kits) directly interact in vivo, and that this interaction is indispensable for the association of both proteins with the box C/D snoRNPs.
Analysis of the Localization of Fibrillarin and Sites of Pre-rRNA Synthesis in the Nucleolus-Like Bodies of Mouse GV Oocytes after Mild Treatment with Proteinase K
SUV39h1 (show SUV39H1 ELISA Kits) associated with HP1 beta (show CBX1 ELISA Kits) in fibrillarin-positive nucleolar regions.
Results suggest that proteasome-dependent processing of fibrillarin occurs upon mercury induction.
This splicing factor (show SLU7 ELISA Kits) was more abundant in hepatocyte nuclei of mice fed genetically-modified soybeans than in control mice.
massive apoptosis was observed in early Fibrillarin(-/-) embryos, showing that fibrillarin is essential for development
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
, pantothenate kinase
, hypothetical protein
, 34 kDa nucleolar scleroderma antigen
, 34-kD nucleolar scleroderma antigen
, RNA, U3 small nucleolar interacting protein 1
, rRNA 2'-O-methyltransferase fibrillarin
, nucleolar protein 1