You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our anti-Glycyl-tRNA Synthetase (GARS) Antibodies

Full name:
anti-Glycyl-tRNA Synthetase Antibodies (GARS)
On www.antibodies-online.com are 59 Glycyl-tRNA Synthetase (GARS) Antibodies from 16 different suppliers available. Additionally we are shipping Glycyl-tRNA Synthetase Kits (16) and Glycyl-tRNA Synthetase Proteins (8) and many more products for this protein. A total of 89 Glycyl-tRNA Synthetase products are currently listed.
Synonyms:
Aat-gly, CG6778, CMT2D, Dmel\\CG6778, DSMAV, fb02f03, gars, GB13467, Gena201, GENA202, GlyRS, GRS, HMN5, MGC79495, Nmf249, RGD1559871, Sgrp23, si:dkey-276i5.1, SMAD1, team, wu:fb02f03
list all antibodies Gene Name GeneID UniProt
GARS 2617 P41250
GARS 353172 Q9CZD3
GARS 297113  

Show all species

Show all synonyms

Most Popular Reactivities for anti-Glycyl-tRNA Synthetase (GARS) Antibodies

Select your species and application

anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

anti-Rat (Rattus) Antibodies:

All available anti-Glycyl-tRNA Synthetase Antibodies

Go to our pre-filtered search.

Top referenced anti-Glycyl-tRNA Synthetase Antibodies

  1. Human Polyclonal GARS Primary Antibody for WB - ABIN392465 : Shiba, Schimmel, Motegi, Noda: Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN392465

  2. Human Polyclonal GARS Primary Antibody for EIA, WB - ABIN360353 : Antonellis, Ellsworth, Sambuughin, Puls, Abel, Lee-Lin, Jordanova, Kremensky, Christodoulou, Middleton, Sivakumar, Ionasescu, Funalot, Vance, Goldfarb, Fischbeck, Green: Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V. in American journal of human genetics 2003 (PubMed)
    Show all 2 references for ABIN360353

  3. Cow (Bovine) Polyclonal GARS Primary Antibody for WB - ABIN2787816 : Förster, Zerressen-Harte, Fürste, Perbandt, Betzel, Erdmann: Comparative X-ray structure analysis of human and Escherichia coli tRNA(Gly) acceptor stem microhelices. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against Glycyl-tRNA Synthetase Interaction Partners

Fruit Fly (Drosophila melanogaster) Glycyl-tRNA Synthetase (GARS) interaction partners

  1. Our findings suggest that mutant GlyRS gains access to ectopic sub-compartments of the motor neuron, providing a possible explanation for the selective neuropathology caused by mutations in a widely expressed gene.

Human Glycyl-tRNA Synthetase (GARS) interaction partners

  1. At the active site, a glycyl-AMP (show APRT Antibodies) molecule is synthesized and is waiting for the transfer of the glycyl moiety to occur.

  2. GlyRS functions as a chaperone that critically supports neddylation.

  3. Data indicate that dimerization is required for the dominant neurotoxicity of disease-associated GARS mutations and provide a rapid, tractable model for studying newly identified GARS variants for a role in human disease.

  4. one of the mRNAs isoforms tightly controls expression and localization of human GARS.

  5. This study reports two crystal structures of human GlyRS variants, in the free form and in complex with tRNA(Gly) respectively, and reveal new aspects of the glycylation mechanism.

  6. GARS mutations are an uncommon cause of Charcot-Marie-Tooth Disease (CMT) in Taiwan. The p.Asp146Tyr and p.Met238Arg mutations are associated with early-onset axonal CMT.

  7. Our findings suggest that mutant GlyRS gains access to ectopic sub-compartments of the motor neuron, providing a possible explanation for the selective neuropathology caused by mutations in a widely expressed gene.

  8. Expression of three CMT-mutant GARS proteins in Drosophila induces defects in motor performance and motor and sensory neuron morphology, and shortens lifespan.

  9. The c.999G>T mutation is a novel mutation of the glycyl-tRNA synthetase gene that has not been previously reported. The phenotype of this family is Charcot-Marie-Tooth disease type 2D, which is first reported in Chinese population.

  10. we propose that the disease-causing L129P mutant of glycyl-tRNA synthetase is linked to a distribution defect in peripheral nerves in vivo.

Mouse (Murine) Glycyl-tRNA Synthetase (GARS) interaction partners

  1. findings link the selective pathology of Charcot-Marie-Tooth disease type 2D to the neomorphic binding activity of GlyRS(CMT2D) that antagonizes the VEGF (show VEGFA Antibodies)-Nrp1 (show NRP1 Antibodies) interaction, meaning the VEGF (show VEGFA Antibodies)-Nrp1 (show NRP1 Antibodies) signalling axis is an actionable target for treating CMT2D

  2. Results indicate that Charcot-Marie-Tooth peripheral neuropathies, type 2D (CMT2D) phenotype is caused by novel pathogenic roles for the mutant GARS that specifically affect peripheral neurons.

  3. a glycyl-tRNA synthetase (GARS) mutation causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy

  4. Gars(C201R) mutation significantly delayed disease onset in the SOD1 (show SOD1 Antibodies)(G93A);Gars(C201R/+) double heterozygous mutant mice and increased lifespan by 29% on the genetic background investigated

Zebrafish Glycyl-tRNA Synthetase (GARS) interaction partners

  1. Data indicate that dimerization is required for the dominant neurotoxicity of disease-associated GARS mutations and provide a rapid, tractable model for studying newly identified GARS variants for a role in human disease.

Pig (Porcine) Glycyl-tRNA Synthetase (GARS) interaction partners

  1. Expression levels of ADSL (show ADSL Antibodies), GARS-AIRS-GART (show GART Antibodies), and DGAT1 (show DGAT1 Antibodies) were higher in longissimus lumborum muscle than in heart or liver tissues

Glycyl-tRNA Synthetase (GARS) Antigen Profile

Antigen Summary

This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

Alternative names and synonyms associated with Glycyl-tRNA Synthetase (GARS)

  • Glycyl-tRNA synthetase (Aats-gly) antibody
  • glycyl-tRNA synthetase (Aats-gly) antibody
  • glycyl-tRNA synthetase (GARS) antibody
  • glycyl-tRNA synthetase (gars) antibody
  • glycyl-tRNA synthetase (glyQ) antibody
  • glycyl-tRNA synthetase (TTHA0543) antibody
  • glycyl-tRNA synthetase (Gars) antibody
  • glycyl-tRNA synthetase (LOC692991) antibody
  • glycyl-tRNA synthetase-like (LOC100512260) antibody
  • Aat-gly antibody
  • CG6778 antibody
  • CMT2D antibody
  • Dmel\\CG6778 antibody
  • DSMAV antibody
  • fb02f03 antibody
  • gars antibody
  • GB13467 antibody
  • Gena201 antibody
  • GENA202 antibody
  • GlyRS antibody
  • GRS antibody
  • HMN5 antibody
  • MGC79495 antibody
  • Nmf249 antibody
  • RGD1559871 antibody
  • Sgrp23 antibody
  • si:dkey-276i5.1 antibody
  • SMAD1 antibody
  • team antibody
  • wu:fb02f03 antibody

Protein level used designations for GARS

Aats-gly-PA , Aats-gly-PB , Aats-gly-PC , CG6778-PA , CG6778-PB , CG6778-PC , glycyl-tRNA synthetase , glycine--tRNA ligase , AP-4-A synthetase , Charcot-Marie-Tooth neuropathy 2D , Charcot-Marie-Tooth neuropathy, neuronal type, D , diadenosine tetraphosphate synthetase , glycine tRNA ligase , glyRS , storage granule protein 23 , glycyl-tran synthetase

GENE ID SPECIES
39644 Drosophila melanogaster
408392 Apis mellifera
463329 Pan troglodytes
475268 Canis lupus familiaris
493218 Xenopus (Silurana) tropicalis
884595 Chlamydia trachomatis D/UW-3/CX
3169948 Thermus thermophilus HB8
100388470 Callithrix jacchus
2617 Homo sapiens
353172 Mus musculus
297113 Rattus norvegicus
337230 Danio rerio
446482 Xenopus laevis
428403 Gallus gallus
408010 Bos taurus
692991 Bombyx mori
100174405 Pongo abelii
100512260 Sus scrofa
Selected quality suppliers for anti-Glycyl-tRNA Synthetase (GARS) Antibodies
Did you look for something else?