Browse our anti-Pyruvate Kinase, Liver and RBC (PKLR) Antibodies

Full name:
anti-Pyruvate Kinase, Liver and RBC Antibodies (PKLR)
On www.antibodies-online.com are 148 Pyruvate Kinase, Liver and RBC (PKLR) Antibodies from 19 different suppliers available. Additionally we are shipping Pyruvate Kinase, Liver and RBC Kits (36) and Pyruvate Kinase, Liver and RBC Proteins (21) and many more products for this protein. A total of 216 Pyruvate Kinase, Liver and RBC products are currently listed.
Synonyms:
cthbp, oip3, Pk-1, PK1, pk3, PKL, Pklg, pklr, pkm2, PKR, PKRL, R-PK, RPK, tcb, thbp1, wu:fd15e01, wu:fi37e08
list all antibodies Gene Name GeneID UniProt
PKLR 18770  
PKLR 5313 P30613
PKLR 24651 P12928

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Most Popular Reactivities for anti-Pyruvate Kinase, Liver and RBC (PKLR) Antibodies

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anti-Mouse (Murine) Antibodies:

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anti-Rat (Rattus) Antibodies:

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Top referenced anti-Pyruvate Kinase, Liver and RBC Antibodies

  1. Human Polyclonal PKLR Primary Antibody for EIA, IHC (p) - ABIN359109 : Wang, Chu, Das, Ren, Hasstedt, Elbein: Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians. in Diabetes 2002 (PubMed)
    Show all 4 references for 359109

  2. Human Polyclonal PKLR Primary Antibody for EIA, IHC (p) - ABIN359110 : Valentini, Chiarelli, Fortin, Dolzan, Galizzi, Abraham, Wang, Bianchi, Zanella, Mattevi: Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia. in The Journal of biological chemistry 2002 (PubMed)
    Show all 4 references for 359110

  3. Human Monoclonal PKLR Primary Antibody for EIA, WB - ABIN781545 : Meza, Alonso-Ferrero, Navarro, Quintana-Bustamante, Valeri, Garcia-Gomez, Bueren, Bautista, Segovia: Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzyme. in Molecular therapy : the journal of the American Society of Gene Therapy 2009 (PubMed)
    Show all 2 references for 781545

  4. Cow (Bovine) Polyclonal PKLR Primary Antibody for IHC, WB - ABIN2776945 : Pendergrass, Williams, Blair, Fenton: Mining for allosteric information: natural mutations and positional sequence conservation in pyruvate kinase. in IUBMB life 2006 (PubMed)

  5. Human Polyclonal PKLR Primary Antibody for IHC, IHC (p) - ABIN4345879 : Kowalski, Nocon, Gamian, Kołodziej, Rakus: Association of C-terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells. in Journal of cellular physiology 2012 (PubMed)

More Antibodies against Pyruvate Kinase, Liver and RBC Interaction Partners

Mouse (Murine) Pyruvate Kinase, Liver and RBC (PKLR) interaction partners

  1. AMPD3 deficiency increases the level of ATP in erythrocytes, but does not improve anemia due to pyruvate kinase deficiency and leads to erythrocyte dysfunction.

  2. Pyruvate kinase deficiency in mice protects against malaria

Human Pyruvate Kinase, Liver and RBC (PKLR) interaction partners

  1. Gene copy number variation (CNV) of the PKLR, FCGR2A (show FCGR2A Antibodies), FCGR2C, and FCGR3 (show CD16 Antibodies) genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.

  2. Genotype-phenotype correlations for the novel missense mutations found in the PKLR gene in PK deficiency among Tunisian cases were investigated by three-dimensional structure analysis.

  3. Data show that pyruvate kinase (PK) activity was decreased in the GATA1 (show GATA1 Antibodies) hemizygous state and PKLR c.1284delA variant.

  4. An update of PKLR gene mutation database has been presented. (Review)

  5. Two Novel Missense Mutations and a 5bp Deletion in the Erythroid-Specific Promoter of the PKLR Gene in Two Unrelated Patients With Pyruvate Kinase Deficient Transfusion-Dependent Chronic Nonspherocytic Hemolytic Anemia.

  6. PKLR promotes colorectal cancer liver colonization through induction of glutathione synthesis.

  7. Pyruvate kinase variants modulate malaria phenotypes in a Thai population.

  8. 661G>A and 1528C>T mutations of PKLR gene are associated with pyruvate kinase deficiency.

  9. Case Report: unknown mutation in the pyruvate kinase gene (PKLR) identified from a neonate with severe jaundice.

  10. This study determined which interactions in the fructose 1,6-bisphosphate binding site of human liver pyruvate kinase contribute to allostery.

Pig (Porcine) Pyruvate Kinase, Liver and RBC (PKLR) interaction partners

  1. The existence of mitochondrial Pyruvate kinase was confirmed by immunological analysis in pig liver mitochondria.

Pyruvate Kinase, Liver and RBC (PKLR) Antigen Profile

Antigen Summary

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Pyruvate Kinase, Liver and RBC (PKLR)

  • pyruvate kinase, liver and RBC (pklr) antibody
  • pyruvate kinase, liver and RBC (PKLR) antibody
  • pyruvate kinase, muscle (pkm) antibody
  • pyruvate kinase liver and red blood cell (Pklr) antibody
  • pyruvate kinase, liver and RBC (Pklr) antibody
  • cthbp antibody
  • oip3 antibody
  • Pk-1 antibody
  • PK1 antibody
  • pk3 antibody
  • PKL antibody
  • Pklg antibody
  • pklr antibody
  • pkm2 antibody
  • PKR antibody
  • PKRL antibody
  • R-PK antibody
  • RPK antibody
  • tcb antibody
  • thbp1 antibody
  • wu:fd15e01 antibody
  • wu:fi37e08 antibody

Protein level used designations for PKLR

pyruvate kinase isozymes R/L , pyruvate kinase, liver and RBC , Pyruvate kinase isozyme R , pyruvate kinase isozymes R/L-like , L-PK , pyruvate kinase PKLR , pyruvate kinase isozymes L/R , R-type/L-type pyruvate kinase , pyruvate kinase 1 , pyruvate kinase isozyme R/L , pyruvate kinase type L , pyruvate kinase, liver and blood cell , red cell/liver pyruvate kinase , Pyruvate kinase isozymes R/L , pyruvate kinase, liver and red blood cell

GENE ID SPECIES
114551 Danio rerio
406183 Canis lupus familiaris
469513 Pan troglodytes
549224 Xenopus (Silurana) tropicalis
719152 Macaca mulatta
100380137 Xenopus (Silurana) tropicalis
100391903 Callithrix jacchus
18770 Mus musculus
398967 Xenopus laevis
5313 Homo sapiens
490425 Canis lupus familiaris
539579 Bos taurus
24651 Rattus norvegicus
100355056 Oryctolagus cuniculus
100533203 Sus scrofa
100716756 Cavia porcellus
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