Browse our ABI1 Proteins (ABI1)

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Abl-Interactor 1 Proteins (ABI1)
On are 8 Abl-Interactor 1 (ABI1) Proteins from 5 different suppliers available. Additionally we are shipping ABI1 Antibodies (103) and ABI1 Kits (4) and many more products for this protein. A total of 124 ABI1 products are currently listed.
ABA INSENSITIVE 1, ABI-1, abi-2, ABI1, abi2b, ablbp3, ABLBP4, aip-1, argbpia, argbpib, AtABI1, DKFZp469P1319, E3b1, F20B18.190, F20B18_190, MGC84356, NAP1, NAP1BP, PROTEIN PHOSPHATASE 2C ABI1, SSH3BP, Ssh3bp1, ssh3bp2, wu:fc66g09, wu:fe48a10, wu:fk56a10, zgc:73174, zgc:153534
list all proteins Gene Name GeneID UniProt
ABI1 10006 Q8IZP0
ABI1 11308 Q8CBW3
ABI1 79249  

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ABI1 Proteins (ABI1) by Origin

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More Proteins for ABI1 Interaction Partners

Arabidopsis thaliana Abl-Interactor 1 (ABI1) interaction partners

  1. Phosphatase ABI1 and okadaic acid-sensitive phosphatases of the PPP family are negative regulators of salt stress-activated SnRK2.4.

  2. ABI1 acts to inhibit MAPKKK18 kinase activity, but also affects MAPKKK18 protein turnover via the ubiquitin-proteasome pathway. SnRK2.6 kinase also seems to be important for the regulation of MAPKKK18 function.

  3. ABI1 regulates the activity and promotes proteasomal degradation of MKKK18.

  4. The role of ABI1 in the activation of nuclear genes during transcription of chloroplast genes

  5. ABI1 (ABA-INSENSITIVE 1) can interact with the U-box E3 ligases PUB12 and PUB13, but is ubiquitinated only when it interacts with ABA receptors in an in vitro assay.

  6. There is direct cross-talk between C/N and non-canonical ABA signalling pathways, regulated by ABI1, in plants.

  7. ABI1 and PP2CA dephosphorylate and inactivate SnRK1 which represses SnRK1 signaling.

  8. Data indicate that PYL8 interacted in vivo with at least five PP2Cs, namely HAB1, HAB2, ABI1, ABI2, and PP2CA.

  9. Two dominant-negative mutations in ABA insensitive1 (abi1-1) and abi2-1 greatly reduced ROS (show ROS1 Proteins) production in mitochondria.

  10. ROP11 protects ABI1 phosphatase activity from inhibition by RCAR1/PYL9 and thus negatively regulates abscissic acid signaling.

Xenopus laevis Abl-Interactor 1 (ABI1) interaction partners

  1. Abi1 scaffold protein (show HOMER1 Proteins) is an essential regulator of cell movement processes required for normal eye development in Xenopus embryos and requires an Src (show SRC Proteins) homology 3 domain-dependent interaction with Wasp (show WASL Proteins) to regulate this complex morphogenetic process

Human Abl-Interactor 1 (ABI1) interaction partners

  1. our findings indicated that ABI1 contributes to the development and progression of hepatocellular carcinoma (HCC (show FAM126A Proteins)) as an oncogene (show RAB1A Proteins) and may serve as a valuable prognostic marker for HCC (show FAM126A Proteins) patients.

  2. these data indicate that HCV exploits host Abi1 protein via NS5A to modulate MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins) signaling pathway for its own propagation.

  3. Suggest that Abi1 acts as a tumor-promoting gene in epithelial ovarian cancer progression, which may lead to unfavorable prognosis.

  4. These results indicate that the alpha4-Abi-1 signaling pathway may mediate acquisition of the drug-resistant phenotype of leukemic cells.

  5. Our data indicate that phosphorylated Abi1 contributes to the invasive properties of colorectal cancer.

  6. Abi1 is expressed at the invasive front of colorectal carcinomas and localizes to the leading edge of lamellipodia in cultured colorectal carcinoma cells.

  7. Data indicate that Abi1 is activated by the c-Abl (show ABL1 Proteins)-Crk-associated substrate (CAS (show BCAR1 Proteins)) pathway, and Abi1 reciprocally controls the activation of its upstream regulator c-Abl (show ABL1 Proteins).

  8. a possible role for Abi1 as a marker for early KRAS mutation in hyperplastic polyps

  9. Breast tumors expressing high levels of Abi1 are significantly associated with early recurrence and worse survival on multivariate analysis.

  10. Down-regulation of E3B1/ABI-1 expression in human carcinomas may play a critical role in tumor progression and in determining disease prognosis.

Mouse (Murine) Abl-Interactor 1 (ABI1) interaction partners

  1. The expression of NESH/Abi-3 (show ABI3 Proteins) caused degradation of endogenous Abi-1, which led to the formation of a NESH/Abi-3 (show ABI3 Proteins)-based WAVE2 (show WASF2 Proteins) complex.

  2. CDK1-mediated phosphorylation of Abi1 attenuates Bcr-Abl-induced F-actin assembly and tyrosine phosphorylation of WAVE complex during mitosis

  3. sential role for Abi1 in embryonic survival and WAVE2 (show WASF2 Proteins) complex integrity

  4. Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.

  5. Abi1 (also known as E3b1) recruits PI3K, via p85 (show ECM1 Proteins), into a multimolecular signaling complex that includes Eps8 (show EPS8 Proteins) and Sos-1 (show SOS1 Proteins)

  6. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins

  7. Altogether these data identify a WAVE2 (show WASF2 Proteins)-Abi1 complex crucial for the normal actin cytoskeleton reorganization and migration of macrophages in response to CSF-1 (show CSF1 Proteins).

  8. c-Abl (show ABL1 Proteins) activates WAVE2 (show WASF2 Proteins) via tyrosine phosphorylation to promote actin remodeling in vivo; Abi-1 forms the crucial link between these two factors

  9. These results show that the interaction between Abi-1 and betaPIX (show ARHGEF7 Proteins) is involved in the formation of growth factor-induced membrane dorsal ruffles.

  10. NESH (Abi-3 (show ABI3 Proteins)), like Abi-1 and Abi-2, is a component of the Abi/WAVE complex, but likely plays a different role in the regulation of c-Abl (show ABL1 Proteins).

ABI1 Protein Profile

Protein Summary

This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10\;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.

Alternative names and synonyms associated with ABI1

  • protein phosphatase 2C 56 (ABI1)
  • abl-interactor 1a (abi1a)
  • abl-interactor 1 (abi1)
  • abl-interactor 1 (ABI1)
  • abl-interactor 2 (abi2)
  • abl-interactor 1b (abi1b)
  • Abl-interactor 1 (Bm1_44660)
  • Abl interactor 1 (abi1)
  • abl-interactor 1 (LOAG_04356)
  • abl-interactor 1 (Abi1)
  • ABA INSENSITIVE 1 protein
  • ABI-1 protein
  • abi-2 protein
  • ABI1 protein
  • abi2b protein
  • ablbp3 protein
  • ABLBP4 protein
  • aip-1 protein
  • argbpia protein
  • argbpib protein
  • AtABI1 protein
  • DKFZp469P1319 protein
  • E3b1 protein
  • F20B18.190 protein
  • F20B18_190 protein
  • MGC84356 protein
  • NAP1 protein
  • NAP1BP protein
  • SSH3BP protein
  • Ssh3bp1 protein
  • ssh3bp2 protein
  • wu:fc66g09 protein
  • wu:fe48a10 protein
  • wu:fk56a10 protein
  • zgc:73174 protein
  • zgc:153534 protein

Protein level used designations for Abl-Interactor 1 Proteins (ABI1)

abl-interactor 1 , abl interactor 1 , abl interactor 2 , Abl-interactor 1 , Abl interactor 1 , abl interactor 1-like , Abelson interactor 1 , Abl-interactor protein 1 long , abl-binding protein 4 , eps8 SH3 domain-binding protein , interactor protein AblBP4 , nap1 binding protein , spectrin SH3 domain-binding protein 1 , abelson interactor 1 , abi-1 , ablphilin-1 , eps8 binding protein , eps8-binding protein , spectrin SH3 domain binding protein 1 , eps8 binding protein (e3B1), alternatively spliced

828714 Arabidopsis thaliana
393711 Danio rerio
447582 Xenopus laevis
450363 Pan troglodytes
493216 Xenopus (Silurana) tropicalis
540815 Bos taurus
548798 Xenopus (Silurana) tropicalis
707698 Macaca mulatta
767738 Danio rerio
6103816 Brugia malayi
100055377 Equus caballus
100173382 Pongo abelii
100195035 Salmo salar
100408906 Callithrix jacchus
100465106 Ailuropoda melanoleuca
9941758 Loa loa
100598819 Nomascus leucogenys
10006 Homo sapiens
11308 Mus musculus
79249 Rattus norvegicus
607247 Canis lupus familiaris
420489 Gallus gallus
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