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anti-Mouse (Murine) Amphiregulin Antibodies:
anti-Human Amphiregulin Antibodies:
anti-Rat (Rattus) Amphiregulin Antibodies:
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Human Polyclonal Amphiregulin Primary Antibody for WB - ABIN610556
Chen, Parsons, Brautigan: Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts. in The Journal of biological chemistry 1994
Show all 2 references for ABIN610556
Human Polyclonal Amphiregulin Primary Antibody for IP - ABIN181313
Johnson, Saeki, Gordon, Shoyab, Salomon, Stromberg: Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon. in The Journal of cell biology 1992
Show all 2 references for ABIN181313
Human Polyclonal Amphiregulin Primary Antibody for IHC, IHC (p) - ABIN4280428
Barton, DAmato, Gordon, Lind, Spoelstra, Babbs, Heinz, Elias, Jedlicka, Jacobsen, Richer: Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo. in Molecular cancer therapeutics 2015
activated alveolar macrophages also exerted a protective effect on the lung tissues by producing high-level amphiregulin in lipopolysaccharide-induced acute lung injury
AREG overexpression in osteoblasts induces a transient high bone mass phenotype in the trabecular compartment of the appendicular skeleton by a growth-related, non-cell autonomous mechanism
AREG-silenced keratinocytes plays an important role in regulation cell proliferation.
Hepatic CD206 (show MRC1 Antibodies)-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection.
Areg may have a role in classically activated macrophages
After activation with IL-33 (show IL33 Antibodies), expression of AREG is a dominant functional signature of gut (show GUSB Antibodies)-associated IL-33 (show IL33 Antibodies)-dependent group 2 innate lymphoid cells. The frequency and number of AREG-expressing ILC2s increases following intestinal injury.
AR induces hHSC fibrogenic activity via multiple mitogenic signaling pathways, and is upregulated in murine and human NASH (show SAMSN1 Antibodies), suggesting that AR antagonists may be clinically useful anti-fibrotics in NAFLD (show TSC2 Antibodies).
hormones and/or factors in addition to E that upregulate AREG can promote mammary gland development and have the potential to affect breast cancer risk associated with pubertal mammary gland development
Our data show that AREG is essential for ultraviolet therapy-induced contact hypersensitivity suppression.
Pre-maturation with cAMP modulators in conjunction with EGF (show EGF Antibodies)-like peptides during in vitro maturation enhances mouse oocyte developmental competence.
LH and AREG decrease BNP (show BNC2 Antibodies) and CNP (show NPPC Antibodies) production in granulosa cells and down-regulate NPR2 (show NPRL2 Antibodies) expression in cumulus cells, which together decreased oocyte cGMP to levels that permit meiotic resumption.
cloning the complete coding region; comparison of endometrial amphiregulin mRNA expression in Meishan and White composite pigs
blocking soluble amphiregulin with a neutralizing antibody also significantly increased apoptotic cell death of HepG2 cells due to treatment with methyl methanesulfonate, cisplatin, or a recombinant p53 (show TP53 Antibodies) adenovirus, suggesting that the function of amphiregulin involved in inhibiting apoptosis may be a common mechanism by which hepatoma cells escape from stimulus-induced apoptosis
Low AREG expression is associated with gastric cancer.
RYR2 (show RYR2 Antibodies), PTDSS1 (show PTDSS1 Antibodies) and AREG are autism susceptibility genes that are implicated in a Lebanese population-based study of copy number variations in this disease.
High Amphiregulin enhances intercellular adhesion molecule-1 (show ICAM1 Antibodies) expression and promotes tumor metastasis in osteosarcoma.
results demonstrate that AREG controls G2/M progression and cytokinesis in keratinocytes via activation of a FoxM1 (show FOXM1 Antibodies)-dependent transcriptional program, suggesting new avenues for treatment of epithelial cancer
High expression of amphiregulin is associated with hepatocellular carcinoma.
Findings show the involvement of amphiregulin and semaphorin-3A (show SEMA3A Antibodies) in the improvement of skin innervations and penetration of nerve fibers into the epidermis.
Altered AREG expression induced by diverse luteinizing hormone receptor (show LHCGR Antibodies) reactivity in granulosa cells may provide a useful marker for oocyte developmental competency
Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf (show RAF1 Antibodies)/MEK (show MAP2K1 Antibodies)/ERK (show EPHB2 Antibodies)/AP-1 (show FOSB Antibodies) pathway.
Our findings implicate amphiregulin as a critical mediator of the estrogen response in ERalpha (show ESR1 Antibodies)-positive breast cancer
Amphiregulin co-operates with bone morphogenetic protein 15 (show BMP15 Antibodies) to increase bovine oocyte developmental competence.
Data suggest that epidermal growth factor receptor (show EGFR Antibodies) B [ErbB (show EGFR Antibodies)] isoforms and their ligands (epidermal growth factor (show EGF Antibodies) [EGF (show EGF Antibodies)], amphiregulin [AREG], and neuregulin-1 (show NRG1 Antibodies) [NRG1 (show NRG1 Antibodies)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
schwannoma-derived growth factor
, amphiregulin (schwannoma-derived growth factor)
, amphiregulin long form
, colorectum cell-derived growth factor
, Schwannoma-derived growth factor
, amphiregulin B