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Human Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN624939
Khan, Sharma, Kumar, Husain, Sharma: Interrelationship and expression profiling of cyclooxygenase and angiogenic factors in Indian patients with multiple myeloma. in Annals of hematology 2013
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Human Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN414353
Retzlaff, Thamm, Ghosh, Ziegler, Haller, Parikh, David: Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis. in Scientific reports 2017
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Mouse (Murine) Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN415585
Nakamura, Suzuki, Shimizu, Miyata, Shishido, Ikeda, Saitoh, Kubota, Takeishi: High Mobility Group Box 1 Promotes Angiogenesis from Bone Marrow-derived Endothelial Progenitor Cells after Myocardial Infarction. in Journal of atherosclerosis and thrombosis 2015
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Rat (Rattus) Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN365582
Koyama, Maebara, Hayashi, Nagae, Tokuyama, Michinaga: Endothelins reciprocally regulate VEGF-A and angiopoietin-1 production in cultured rat astrocytes: implications on astrocytic proliferation. in Glia 2012
Mouse (Murine) Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN2683441
Bi, Niu, Ding, Zhang, Yang, Gu: Angiopoietin-1 attenuates angiotensin II-induced ER stress in glomerular endothelial cells via a Tie2 receptor/ERK1/2-p38 MAPK-dependent mechanism. in Molecular and cellular endocrinology 2016
Zebra fish (Danio rerio) morphants showed that mild knock down of Ang-1 produces a small-brained phenotype that could be rescued with Ang-1 mRNA.
These results indicate that the Angpt-Tie2 (show TEK ELISA Kits) system is essential for SC integrity. The impairment of this system underlies POAG-associated pathogenesis, supporting the possibility that Tie2 (show TEK ELISA Kits) agonists could be a therapeutic option for glaucoma.
we demonstrate that targeted Ang-1 overexpression attenuates myofibroblast activation and interstitial collagen I accumulation, inhibits the upregulation of transforming growth factor beta1 and subsequent phosphorylation of Smad 2 (show SMAD2 ELISA Kits)/3, dampens renal inflammation, and stimulates the growth of peritubular capillaries in the obstructed kidney.
Hydroxysafflor yellow A promotes angiogenesis in ischemic hindlimb via the angiopoietin 1/ (show TEK ELISA Kits) Tie-2 signaling pathway.
COMP (show COMP ELISA Kits)-Ang1 can enhance BMP2 (show BMP2 ELISA Kits)-induced cranial bone regeneration with increased pericyte recruitment. Combined delivery of the proteins might be a therapeutic strategy to repair cranial bone damage.
Hematopoietic stem cells regulate the regeneration of their niche by secreting Angpt1.
Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.
Ang-1 strongly enhances skeletal muscle regeneration in response to fiber injury and that this effect is mediated through induction of the myogenesis program in muscle progenitor cells and the angiogenesis program in endothelial cells.
These results suggest that PRP extract prevents endotoxin-induced pulmonary edema mainly through Ang (show ANG ELISA Kits)-Tie2 (show TEK ELISA Kits) signaling, and PRP extract could be a potential therapeutic strategy for sepsis-induced pulmonary edema
E2 increases Ang-1 and enhances capillary density in brain under basal conditions through estrogen receptor-alpha (show ESR1 ELISA Kits), priming the middle cerebral artery territory for survival after experimental focal ischemia
The important role of Ang-1 in the activation of mast cells, and a potential therapeutic effect of Ang-1 on anaphylaxis diseases.
Ang-1 specifically increases circulating Gr1(+ )inflammatory monocytes and increases monocyte/macrophage retention in atherosclerotic plaques, thereby contributing to development of atherosclerosis.
NOX2 (show CYBB ELISA Kits), NOX4 (show NOX4 ELISA Kits), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 signaling and angiogenic responses in endothelial cells.
ANG-1, ANG-2 (show ANGPT2 ELISA Kits) and TIE-2 (show TEK ELISA Kits) levels were significantly increased in placenta of non-complicated ART pregnancies compared to placentas from spontaneous conception.
study is the first one to report Ang1 capacity to induce MIP-1beta (show CCL4 ELISA Kits) gene expression, protein synthesis and release from neutrophils, and that these effects are mediated by PI3K (show PIK3CA ELISA Kits), p38 MAPK (show MAPK14 ELISA Kits) and MEK (show MAP2K1 ELISA Kits) activation and downstream NF-kappaB (show NFKB1 ELISA Kits) activation
In this study, we found that angiopoietins and Tie receptors were highly expressed in cervical cancer cells. Tie-2 (show TEK ELISA Kits) expression in tumor cells predicted poorer prognosis.Our data support that dual inhibition of Ang-1 and Ang-2 (show ANGPT2 ELISA Kits) may be an alternative target for anti-angiogenic adjuvant therapy in advanced or recurrent cervical squamous cell cancer.
Data show that fibulin-5 (show FBLN5 ELISA Kits) strongly binds to the endothelial cell surface reducing endothelial cell viability and interfering with the signaling pathways of the Ang-1/TIE-2 (show TEK ELISA Kits) receptor axis.
Ang-1 is not a predictive and clinically relevant biomarker in pulmonary hypertension
We could therefore conclude that angiogenesis is an important event in the development of common skin warts, and the upregulation of both Ang1 and -2 and their binding receptor Tie2 (show TEK ELISA Kits) may play a role in the angiogenesis associated with the development of these lesions.
In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (show ANGPT2 ELISA Kits) Ang-1, but not the receptor binding domain of Ang-2 (show ANGPT2 ELISA Kits), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (show MAPK1 ELISA Kits) signaling in the presence of both Ang-1 and fibronectin (show FN1 ELISA Kits)
Angiopoietin 1 was predominantly present in the maturing glomeruli.
The expression of ANGPT1 has already been studied during metanephric glomerulogenesis, but it remains to be elucidated during the development of the embryonic mesonephros.
Attenuates H2O2-induced stress-activated protein kinase (show CDK7 ELISA Kits) (SEK)1 (show MAP2K4 ELISA Kits)/JNK (show MAPK8 ELISA Kits) phosphorylation through the PI 3 (show PI3 ELISA Kits)-kinase/Akt (show AKT1 ELISA Kits) pathway and inhibits the apoptosis of vascular endothelial cells induced by oxidative stress.
Estrogen-dependent control of Ang-1 expression plays an important role in stabilizing meningeal microvessel and maintaining healthy microvascular networks.
Angiopoietin-1 receptor Tie2 (show TEK ELISA Kits) distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells.
inhibition of NO production by Ang-1, via phosphorylation of eNOS (show NOS3 ELISA Kits) on Thr (show TRH ELISA Kits)(497) by PKC zeta (show PRKCZ ELISA Kits), is responsible, at least in part, for inhibition of VEGF (show VEGFA ELISA Kits)-stimulated endothelial permeability by Ang-1.
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
, angiopoietin 1