|Application / Reactivity||Rat (Rattus)||Mouse (Murine)||Human|
|ELISA||8 Antibodies||20 Antibodies||32 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies||1 Antibodies||2 Antibodies|
|Immunocytochemistry (ICC)||2 Antibodies||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies||11 Antibodies|
|Immunohistochemistry (IHC)||8 Antibodies||14 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||2 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||8 Antibodies||9 Antibodies|
|Western Blotting (WB)||17 Antibodies||38 Antibodies|
|Flow Cytometry (FACS)||2 Antibodies|
|Immunofluorescence (IF)||1 Antibodies|
|Antigen||Angiopoietin 2 (ANGPT2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Angiopoietin 2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-Angiopoietin 2 AntibodyTarget Details Angiopoietin 2 Application Details Handling References for anti-Angiopoietin 2 Antibody (ABIN1450125) Images
|Cross-Reactivity (Details)||Species reactivity (tested):Human, Mouse, Rat.|
|Purification||Affinity chromatography purified via peptide column|
|Immunogen||18 amino acid synthetic peptide near the carboxy terminus of Human ANGPT2|
Target Details Angiopoietin 2Product Details anti-Angiopoietin 2 Antibody Application Details Handling References for anti-Angiopoietin 2 Antibody (ABIN1450125) Images back to top
|Alternative Name||Angiopoietin-2 (ANGPT2 Antibody Abstract)|
|Background||Angiopoietin-2 (ANGPT2) is a member of the Ang family, a family of angiogenic factors that play major roles in angiogenesis during the development and growth of human cancers, but also during lymphangiogenesis. ANGPT2 is generally considered an antagonist of ANGPT1 and endothelial TEK tyrosine kinase (TIE-2, TEK). ANGPT2 disrupts the vascular remodeling ability of ANGPT1 and is thought to induce endothelial cell apoptosis, resulting in vessel regression. Expression of ANGPT2 has been linked to invasive and metastatic phenotypes of gliomas and other cancers .Synonyms: ANG-2, ANG2, ANGPT2|
|Research Area||Growth Factors|
Application DetailsProduct Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Handling References for anti-Angiopoietin 2 Antibody (ABIN1450125) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details References for anti-Angiopoietin 2 Antibody (ABIN1450125) Images back to top
|Buffer||PBS containing 0.02 % Sodium Azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-Angiopoietin 2 Antibody (ABIN1450125)Product Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details Handling Images back to top
Yang, Ho: "Computational investigation of nanohole array based SPR sensing using phase shift." in: Optics express, Vol. 17, Issue 13, pp. 11205-16, 2009 (PubMed).
Hu, Cheng: "Angiopoietin-2: development of inhibitors for cancer therapy." in: Current oncology reports, Vol. 11, Issue 2, pp. 111-6, 2009 (PubMed).
Bach, Uddin, Burke: "Angiopoietins in malignancy." in: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, Vol. 33, Issue 1, pp. 7-15, 2007 (PubMed).
Lobov, Brooks, Lang: "Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 17, pp. 11205-10, 2002 (PubMed).
Maisonpierre, Suri, Jones et al.: "Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis." in: Science (New York, N.Y.), Vol. 277, Issue 5322, pp. 55-60, 1997 (PubMed).
ImagesProduct Details anti-Angiopoietin 2 Antibody Target Details Angiopoietin 2 Application Details Handling References for anti-Angiopoietin 2 Antibody (ABIN1450125) back to top