anti-Human AXL antibody for Enzyme Immunoassay

Recommended AXL Antibody (supplied by: Log in to see )

Antigen
AXL Receptor tyrosine Kinase (AXL) Antibodies
  • JTK11
  • UFO
  • AI323647
  • Ark
  • Tyro7
  • Ufo
  • AXL receptor tyrosine kinase
  • Axl receptor tyrosine kinase
  • AXL
  • Axl
Epitope
C-Term
27
24
19
18
18
16
14
12
12
11
10
9
8
6
6
6
6
5
5
5
4
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
248
105
63
5
2
2
1
1
1
1
Host
Rabbit
173
83
33
4
1
Clonality
Polyclonal
Conjugate
This AXL antibody is un-conjugated
14
12
10
8
8
7
7
7
6
6
6
6
6
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
184
107
86
54
29
26
14
10
7
4
4
2
2
2
1
1
1
1
1
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Catalog No. ABIN359785
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN359784 EIA WB Rabbit Ig N-Term Log in to see Polyclonal 4
1 ABIN359786 EIA WB Rabbit Ig Log in to see Polyclonal 4
1 ABIN1105479 EIA IF WB Mouse IgG1 Log in to see 7-00E-010 1
1 ABIN4620333 EIA IF IHC (p) WB Mouse IgG1 Log in to see 7-00E-010

General

Antigen AXL Receptor tyrosine Kinase (AXL) Antibodies
Epitope C-Term
(27), (24), (19), (18), (18), (16), (14), (12), (12), (11), (10), (9), (8), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(248), (105), (63), (5), (2), (2), (1), (1), (1), (1)
Host Rabbit
(173), (83), (33), (4), (1)
Clonality
Polyclonal
Conjugate This AXL antibody is un-conjugated
(14), (12), (10), (8), (8), (7), (7), (7), (6), (6), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(184), (107), (86), (54), (29), (26), (14), (10), (7), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-AXL Antibody

Target Details AXL Application Details Handling References for anti-AXL antibody (ABIN359785) Images
Specificity This antibody reacts to AXL.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human AXL.
Isotype Ig

Target Details AXL

Product Details anti-AXL Antibody Application Details Handling References for anti-AXL antibody (ABIN359785) Images back to top
Antigen
Alternative Name AXL / UFO (AXL Antibody Abstract)
Background AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.Synonyms: Tyrosine-protein kinase receptor UFO
Gene ID 558, 9606
UniProt P30530
Research Area Kinases/Phosphatases
Pathways RTK Signaling, Cellular Response to Molecule of Bacterial Origin

Application Details

Product Details anti-AXL Antibody Target Details AXL Handling References for anti-AXL antibody (ABIN359785) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-AXL Antibody Target Details AXL Application Details References for anti-AXL antibody (ABIN359785) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-AXL antibody (ABIN359785)

Product Details anti-AXL Antibody Target Details AXL Application Details Handling Images back to top
Background publications

Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." in: Oncogene, Vol. 8, Issue 12, pp. 3403-10, 1993

Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: "A novel putative tyrosine kinase receptor with oncogenic potential." in: Oncogene, Vol. 6, Issue 11, pp. 2113-20, 1991

OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, 1991

Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: "Putative tyrosine kinases expressed in K-562 human leukemia cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, 1991

Images

Product Details anti-AXL Antibody Target Details AXL Application Details Handling References for anti-AXL antibody (ABIN359785) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-AXL Receptor tyrosine Kinase (AXL) (C-Term) antibody (ABIN359785) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-AXL Receptor tyrosine Kinase (AXL) (C-Term) antibody (ABIN359785) Western blot analysis of anti-AXL C-term Pab in SKBR3 cell lysate. AXL (arrow) was de...