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Human BDNF ELISA Kit for Sandwich ELISA - ABIN624945
Liu, Jiao, Wang, Bu, Yao, Xiang, Wang, Wang, Deng, Li, Zhou, Zhou, Wang: Associations Between ApoE?4 Carrier Status and Serum BDNF Levels--New Insights into the Molecular Mechanism of ApoE?4 Actions in Alzheimer's Disease. in Molecular neurobiology 2015
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Rat (Rattus) BDNF ELISA Kit for Sandwich ELISA - ABIN2683535
Lyons, Mamounas, Ricaurte, Coppola, Reid, Bora, Wihler, Koliatsos, Tessarollo: Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. in Proceedings of the National Academy of Sciences of the United States of America 2000
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Rat (Rattus) BDNF ELISA Kit for Sandwich ELISA - ABIN411258
Uysal, Sisman, Dayi, Ozbal, Cetin, Baykara, Aksu, Tas, Cavus, Gonenc-Arda, Buyuk: Acute footshock-stress increases spatial learning-memory and correlates to increased hippocampal BDNF and VEGF and cell numbers in adolescent male and female rats. in Neuroscience letters 2012
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Mouse (Murine) BDNF ELISA Kit for Sandwich ELISA - ABIN2683534
Kovalchuk, Hanse, Kafitz, Konnerth: Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. in Science (New York, N.Y.) 2002
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Rat (Rattus) BDNF ELISA Kit for Sandwich ELISA - ABIN365374
Madhyastha, Sekhar, Rao: Resveratrol improves postnatal hippocampal neurogenesis and brain derived neurotrophic factor in prenatally stressed rats. in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2013
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Human BDNF ELISA Kit for Sandwich ELISA - ABIN411257
Shi, You, Yuan, Zhang, Li, Hou: Plasma BDNF and tPA are associated with late-onset geriatric depression. in Psychiatry and clinical neurosciences 2010
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Rabbit BDNF ELISA Kit for Sandwich ELISA - ABIN572355
Chung, Kim, Im, Yoo, Choi, Hwang, Won, Chang, Cho, Hwang, Moon: Neuroprotective effects of adipose-derived stem cells against ischemic neuronal damage in the rabbit spinal cord. in Journal of the neurological sciences 2012
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Mouse (Murine) BDNF ELISA Kit for Sandwich ELISA - ABIN411259
Jones, Reichardt: Molecular cloning of a human gene that is a member of the nerve growth factor family. in Proceedings of the National Academy of Sciences of the United States of America 1990
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Rat (Rattus) BDNF ELISA Kit for Sandwich ELISA - ABIN416070
Wang, Liu, Jin, Dai, Zhao, Xie, Liu, Yu, Ma: Interaction of PFOS and BDE-47 co-exposure on thyroid hormone levels and TH-related gene and protein expression in developing rat brains. in Toxicological sciences : an official journal of the Society of Toxicology 2011
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Human BDNF ELISA Kit for Sandwich ELISA - ABIN365224
Kim, Song, So, Lee, Song, Kim: Increase of circulating BDNF levels and its relation to improvement of physical fitness following 12 weeks of combined exercise in chronic patients with schizophrenia: a pilot study. in Psychiatry research 2015
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In conclusion, BDNF 196G/A genotype was found to be more frequent among obese patients compared to the non-obese individuals, but it was not significantly related to OSAS in the present study. BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups.
BDNF promotes hESC-NSC growth in vitro through crosstalk with the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway.
We discuss methodological shortcomings of our study and potential differences in the temporal dynamics of how IGF-1 (show IGF1 ELISA Kits), VEGF (show VEGFA ELISA Kits) and BDNF may be affected by exercise and to what extent these differences may have led to the negative findings reported here.
Patients affected by depressive disorders showed an increase of brain-derived neurotrophic factor serum concentration after a 2-week treatment with agomelatine. The increase of brain-derived neurotrophic factor levels was found to be greater in patients with lower brain-derived neurotrophic factor levels and marked anhedonia at baseline.
There was a positive correlation between BDNF and progesterone in controls. In conclusion, primary pvarian insufficiency(POI) patients show significantly lower BDNF plasma concentration and it correlates with the duration of amenorrhea. This observation brings important potential insights to the pathology of POI.
Most biomarkers (IL-6 (show IL6 ELISA Kits), IL-8 (show IL8 ELISA Kits), TNF-alpha (show TNF ELISA Kits), TBARS and protein carbonyl) and BDNF did not differ significantly between patients and controls.
Authors modeled the long-term effects of chronic stress exposure in a novel mouse model that has been genetically modified to express a humanized BDNF (hBDNF) coding transcript via endogenous mouse promoters that has yet to be behaviorally phenotyped.
The aim of the current review was to provide an overview of the role of BDNF/TrkB (show NTRK2 ELISA Kits) pathways in the pathogenesis of breast cancer and its value as a potential therapeutic target.
We hypothesize that BDNF in the developing brain regulates fear circuit plasticity during a sensitive period in early adolescence, and alterations in BDNF expression (genetic or environmental) have a persistent impact on fear behavior and fear-related disorders.
BDNF polymorphisms might contribute to the risk of epilepsy in Malaysian Indians and Chinese.
A critical period of susceptibility to cigarette smoke exposure exists in the prenatal and early postnatal period, which results a downregulation in brain-derived neurotrophic factor/tyrosine kinase receptor B (show NTRK2 ELISA Kits) signaling in the hippocampus and enhances depression-like behaviors later in life.
Deletion of Bdnf in DRG neurons leads to a temporary dysregulation of miR-1.
Excitatory synaptic activation-dependent up-regulation of XBP1 (show XBP1 ELISA Kits) directly facilitated transcriptional activation of BDNF. BDNF in turn drove its own expression via IRE1 (show ERN1 ELISA Kits)-XBP1 (show XBP1 ELISA Kits) pathway in a protein kinase A-dependent manner. Exogenous treatment with BDNF promoteSynaptic activity- and BDNF-dependent distinct activation of dendritic IRE1 (show ERN1 ELISA Kits)-XBP1 (show XBP1 ELISA Kits) cascade drives BDNF expression in cell soma and may be involved in dendritic extension.
High BDNF expression is associated with neuropathic pain.
The authors show that BDNF acts cell autonomous and autocrine, as wildtype neurons are not capable of rescuing growth deficits in neighboring MeCP2 deficient neurons in vitro and in vivo.
BDNF acts retrogradely on TrkB (show NTRK2 ELISA Kits) in climbing fibers , and facilitates elimination of climbing fibers synapses from Purkinje cells somata during the third postnatal week.
EGCG significantly ameliorated insulin (show INS ELISA Kits) resistance and cognitive disorder by up-regulating the insulin receptor substrate-1 (IRS-1 (show IRS1 ELISA Kits))/AKT (show AKT1 ELISA Kits) and ERK (show EPHB2 ELISA Kits)/cAMP response element binding protein (CREB (show CREB ELISA Kits))/brain-derived neurotrophic factor (BDNF) signaling pathways.
CTCF (show CTCF ELISA Kits) knockdown attenuates fear-conditioning-induced hippocampal gene expression of key learning genes and loss of long-range interactions at the BDNF and Arc (show NOL3 ELISA Kits) loci.
Results suggest that activity-dependent BDNF signaling is critical for regulating oscillatory activity, which may contribute to altered behavior.
One of the modulators of TOR (show FRAP1 ELISA Kits) is brain-derived neurotrophic factor (BDNF), which activates the TOR (show FRAP1 ELISA Kits) signaling pathway to promote protein synthesis, synapse strengthening, and the creation of new neural networks.findings demonstrate that TOR (show FRAP1 ELISA Kits) activation in old animals occurs in the early phase of consolidation, and follows a pattern identical to that of BDNF expression.
These results suggest an involvement of the BDNF/TrkB (show NTRK2 ELISA Kits) system in the regulation of food intake and energy balance in zebrafish, as in mammals
BDNF-TrkB (show NTRK2 ELISA Kits) influences the expression level of components of chemokine (show CCL1 ELISA Kits) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.
Light regulates the expression of the BDNF/TrkB2 (show NTRK2 ELISA Kits) system in the adult zebrafish retina.
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (show RACGAP1 ELISA Kits) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (show PARD3 ELISA Kits)) protein.
the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons
The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (show NTRK2 ELISA Kits) in zebrafish.
The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript
Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (show HTT ELISA Kits) knockdown in zebrafish.
Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.
BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG ELISA Kits) .
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (show POMC ELISA Kits)-derived alphaMSH (show POMC ELISA Kits), and that the light controls the biosynthesis and secretion of BDNF and of POMC (show POMC ELISA Kits) end-products.
BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.
BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.
BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis
BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.
PACAP stimulates the expression of BDNF transcript IV.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.
Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (show MMP9 ELISA Kits) and MMP-2 (show MMP2 ELISA Kits), caspase-3 (show CASP3 ELISA Kits) and BDNF
These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (show INS ELISA Kits) and leptin (show LEP ELISA Kits).
Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.
Study showed that complex relationships exist between BDNF/TrkB (show NTRK2 ELISA Kits) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence
In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (show Arc ELISA Kits) expressions are strongly correlated with spontaneous physical activity.
A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.
In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
, brain derived neurothrophic factor
, brain derived neurotrophic factor
, anorexia BDNF
, brain-derived neurotrophic factor
, neurotrophic factor