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Human BDNF Protein expressed in Escherichia coli (E. coli) - ABIN1046638
Jones, Reichardt: Molecular cloning of a human gene that is a member of the nerve growth factor family. in Proceedings of the National Academy of Sciences of the United States of America 1990
Show all 2 references for ABIN1046638
Human BDNF Protein expressed in Escherichia coli (E. coli) - ABIN2681231
Skup: BDNF and NT-3 widen the scope of neurotrophin activity: pharmacological implications. in Acta neurobiologiae experimentalis 1994
Human BDNF Protein expressed in Escherichia coli (E. coli) - ABIN413062
Kobayashi, Saito, Sato, Furusawa, Hosokawa, Tsutsumi, Asada, Kamada, Ohshima, Hisanaga: Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. in The Journal of biological chemistry 2014
Human BDNF Protein expressed in Wheat germ - ABIN1346621
Martin Bauknight, Chakrabarty, Hwang, Malone, Joshi, Bruce, Sander Connolly, Winfree, Cunningham, Martin, Haque: Convection enhanced drug delivery of BDNF through a microcannula in a rodent model to strengthen connectivity of a peripheral motor nerve bridge model to bypass spinal cord injury. in Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2012
BDNF-TrkB (show NTRK2 Proteins) influences the expression level of components of chemokine (show CCL1 Proteins) signaling including Cxcr4b, and the generation of progenitors of mechanoreceptors, at the level of expression of Atoh1a-Atp2b1a.
Light regulates the expression of the BDNF/TrkB2 (show NTRK2 Proteins) system in the adult zebrafish retina.
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (show RACGAP1 Proteins) (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3 (show PARD3 Proteins)) protein.
the results demonstrate that bdnf mediates non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons
The present results demonstrate that there is a parallel time-related decline in the expression of BDNF and TrkB (show NTRK2 Proteins) in zebrafish.
The cloning and analysis of three additional zebrafish (Danio rerio) BDNF gene exons and two associated promoters, is reported. Among them are two exons that generate a novel tripartite mature transcript
Loss of BDNF is a major cause of the developmental abnormalities seen with huntingtin (show HTT Proteins) knockdown in zebrafish.
Together these results suggest an important role of BDNF in the maintenance and regeneration of the olfactory system.
BDNF suppresses neuromuscular junction maturation through cAMP-PKA signaling pathway
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein (show MAG Proteins) .
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
In the Xenopus melanotrope, BDNF biosynthesis and processing occur along the secretory granule maturation axis, together with that of POMC (show POMC Proteins)-derived alphaMSH (show POMC Proteins), and that the light controls the biosynthesis and secretion of BDNF and of POMC (show POMC Proteins) end-products.
BDNF released from the neural lobe of the pituitary gland acts as a neurohormone stimulating the secretory activity of the melanotrope cells in the intermediate pituitary lobe.
BDNF influences synaptic connectivity in multiple ways, promoting not only the morphological maturation of axonal arbors but also their stabilization, but also their stabilization.
BDNF, in addition to its neural and hormonal roles, can be released as a neurohormone from the neural pituitary lobe of X. laevis
BDNF induces glial cell proliferation as well as axonal outgrowth and myelination in vivo.
PACAP stimulates the expression of BDNF transcript IV.
Study showed that complex relationships exist between BDNF/TrkB (show NTRK2 Proteins) gene expression and interneuron marker gene expression that appear to be dependent on the presence of testosterone at adolescence
In a monkey model, cortical BDNF and activity regulated cytoskeletal-associated protein ARC (show Arc Proteins) expressions are strongly correlated with spontaneous physical activity.
A SNP is present in rhesus macaques and is able to affect BDNF peripheral levels, thus making this primate model a fundamental tool to study gene by environment interactions involving the BDNF gene.
In monkey the decline of the BDNF protein level started earlier in the sensory and motor neocortical areas than in the association neocortical areas.
Findings suggest that rapid pro brain-derived neurotrophic factor increases following status epilepticus are due in part to reduced cleavage.
Findings show that mecamylamine-induced nicotine withdrawal disrupts cognitive control processes and these changes are linked to perturbations in frontostriatal brain-derived neurotrophic factor signaling.
The present study hypothesized that modulation of BDNF expression and processing may be the underlying mechanism by which stimulation of the Baihui (DU20) acupoint exerts its neuroprotective effect
These results provide initial evidence that surgery reduces BDNF expression and neurogenesis in the hippocampus.
the BDNF/TrkB (show NTRK2 Proteins) pathway facilitates persistent activity whereas the proBDNF/p75NTR (show NGFR Proteins) pathway inhibits this mnemonic property of entorhinal pyramidal neurons.
The data of this study suggested that short-term exposure to hyperoxic conditions can affect the regulation and expression of BDNF potentially leading to alterations in neural development.
Results identified Fyn kinase as a molecular mediator of BDNF signaling that activates Erk1/2 and promotes oligodendrocyte myelination
that BDNF expressed in taste receptor cells is required to maintain normal levels of innervation in adulthood
BDNF expression levels in hypothalamic and adipose tissue were markedly down-regulated in mice with monosodium glutamate (show GRIN1 Proteins) induced obesity.
Study indicates that diminished mature BDNF trophic signaling through the TrkB (show NTRK2 Proteins) receptor, rather than an induction in proBDNF, is a main contributing factor to the vulnerability of striatal neurons in the zQ175 HD mouse model
peripheral vascular reactivity and serum BDNF responses to exercise training are impaired by the BDNF Val66Met polymorphism; such responsiveness is associated with serum BDNF concentrations in healthy subjects
Results suggest that the role of NRN1 (show NRN1 Proteins) seems to be not independent of BDNF in schizophrenia-spectrum and bipolar disorders.
The present meta-analysis excludes a clinically relevant effect of BDNF Val66Met on antipsychotic drug response per se.
Crossfit training changes brain-derived neurotrophic factor and irisin (show FNDC5 Proteins) levels at rest, after wingate and progressive tests, and improves aerobic capacity and body composition of young physically active men and women
The Val66Met single-nucleotide polymorphism in the BDNF gene affects the rate of locomotor adaptation after stroke.
The gene-environment combination of PRKCG (show PRKCG Proteins) rs3745406 C allele, BDNF rs6265 G allele and high level of negative life events was significantly associated with major depressive disorder.
Compared to controls, the sleep deprived group showed higher serum BDNF levels.
Results suggest an up-regulated expression of a specific brain-derived neurotrophic factor transcript in patients with TLE, an effect that seems to be dependent on the use of specific drugs.
Expression of brain-derived neurotrophic factor (BDNF) and the serotonin transporter (show SLC6A4 Proteins) (5-HTT (show SLC6A4 Proteins))have been linked with major depressive disorder.
These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin (show INS Proteins) and leptin (show LEP Proteins).
Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin factor (BDNF) signaling pathway.
Taken together, these data indicate that recurrent tethering stress in sows over 4.5 years results in a loss of neurotrophic support by BDNF, mediated by an overactive neuroendocrine system.
FiO2 used for resuscitation affects matrix metalloproteinases MMP-9 (show MMP9 Proteins) and MMP-2 (show MMP2 Proteins), caspase-3 (show CASP3 Proteins) and BDNF
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
brain-derived neurotrophic factor
, brain derived neurotrophic factor
, anorexia BDNF
, brain derived neurothrophic factor
, neurotrophic factor