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Human Calm2 Protein expressed in Escherichia coli (E. coli) - ABIN2005215
Shimizu, Inai, Nakazawa: The use of pethidine as pre-medication to prevent anoxic spells in patients with tetralogy of Fallot. in Pediatrics international : official journal of the Japan Pediatric Society 2005
Human Calm2 Protein expressed in Wheat germ - ABIN1347887
Lin, Hsieh, Lin, Fang, Yang, Tsai, Chiang, Pan, Chen: Label-free detection of protein-protein interactions using a calmodulin-modified nanowire transistor. in Proceedings of the National Academy of Sciences of the United States of America 2010
Calmodulin 2 Mutation N98S Is Associated with Unexplained Cardiac Arrest in Infants Due to Low Clinical Penetrance Electrical Disorders.
5 novel de novo CALM2 (show CALM1 Proteins) mutations in association with long-QT syndrome and exertioninduced arrhythmias.(p.N98S, p.N98I, p.D134H, p.D132E, p.Q136P)
CaM-2-ext interacts biochemically with the C-terminus of Ca(v)2.3 similar to the classical CaM-2 as shown by co-immunoprecipitation
Human calmodulin (show CALM1 Proteins) mutations disrupt calcium binding to the protein and are associated with cardiac arrest in early infancy.
The 1.35 A structure of Ca(2 (show CA2 Proteins)+)-bound calmodulin (show CALM1 Proteins) in complex with the DIII-IV linker of Na(V)1.5 suggests that Ca(2 (show CA2 Proteins)+)/CaM (show CALM1 Proteins) destabilizes binding of the inactivation gate to its receptor, biasing inactivation toward more depolarized potentials.
These findings suggest that the CALM2 (show CALM1 Proteins) gene may be a genetic determinant of hip Osteoarthritis.
P53 (show TP53 Proteins) protein stimulates CAMII gene expression in 041 cells.
These results suggest that calmodulin (show CALM1 Proteins) plays a crucial role in the processes of Ca(2 (show CA2 Proteins)+)-induced neuronal cell death and the possibility that the blockage of calmodulin (show CALM1 Proteins) attenuates brain injury after cerebral ischemia.
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
, phosphorylase kinase delta
, prepro-calmodulin 2