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Browse our CSF1 Proteins (CSF1)

Full name:
Colony Stimulating Factor 1 (Macrophage) Proteins (CSF1)
On are 71 Colony Stimulating Factor 1 (Macrophage) (CSF1) Proteins from 13 different suppliers available. Additionally we are shipping CSF1 Antibodies (174) and CSF1 Kits (63) and many more products for this protein. A total of 325 CSF1 products are currently listed.
C87615, CSF-1, CSF1, csf1-1, Csfm, MCSF, op, zgc:172186
list all proteins Gene Name GeneID UniProt
CSF1 1435 P09603
CSF1 78965  
CSF1 12977 P07141

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CSF1 Proteins (CSF1) by Origin

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Top referenced CSF1 Proteins

  1. Rat (Rattus) CSF1 Protein expressed in HEK-293 - ABIN2666557 : Erblich, Zhu, Etgen, Dobrenis, Pollard: Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits. in PLoS ONE 2011 (PubMed)
    Show all 7 references for ABIN2666557

  2. Human CSF1 Protein expressed in HEK-293 - ABIN2666670 : Hodge, Collier, Pavlos, Kirkland, Nicholson: M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts. in PLoS ONE 2011 (PubMed)
    Show all 7 references for ABIN2666670

  3. Mouse (Murine) CSF1 Protein expressed in HEK-293 - ABIN2666672 : MacDonald, Palmer, Cronau, Seppanen, Olver, Raffelt, Kuns, Pettit, Clouston, Wainwright, Branstetter, Smith, Paxton, Cerretti, Bonham, Hill, Hume: An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation. in Blood 2010 (PubMed)
    Show all 6 references for ABIN2666672

  4. Human CSF1 Protein expressed in Human Cells - ABIN2004779 : Pandit, Bohm, Jancarik, Halenbeck, Koths, Kim: Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor. in Science (New York, N.Y.) 1993 (PubMed)
    Show all 4 references for ABIN2004779

  5. Mouse (Murine) CSF1 Protein expressed in Human Cells - ABIN2008633 : Tokai, Kawasaki, Kikuchi, Ouchi: Cloning and characterization of the CSF1 gene of Saccharomyces cerevisiae, which is required for nutrient uptake at low temperature. in Journal of bacteriology 2000 (PubMed)
    Show all 4 references for ABIN2008633

  6. Human CSF1 Protein expressed in Yeast - ABIN2004781 : Fan, Fan, Gewant, Royce, Nanes, Rubin: Increasing membrane-bound MCSF does not enhance OPGL-driven osteoclastogenesis from marrow cells. in American journal of physiology. Endocrinology and metabolism 2001 (PubMed)
    Show all 4 references for ABIN2004781

  7. Human CSF1 Protein expressed in Escherichia coli (E. coli) - ABIN413611 : Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ... in Annals of the rheumatic diseases 2010 (PubMed)

More Proteins for CSF1 Interaction Partners

Cow (Bovine) Colony Stimulating Factor 1 (Macrophage) (CSF1) interaction partners

  1. the high level of colony-stimulating factor 1 expression during bovine pregnancy in uteroplacental tissues is consistent with its proposed role in placental physiology

  2. results suggest that leukemia inhibitory factor (show LIF Proteins) and macrophage-colony stimulating factor (show CSF2 Proteins) are produced in the endometrium and may play different roles in early and mid-pregnancy

Rhesus Monkey Colony Stimulating Factor 1 (Macrophage) (CSF1) interaction partners

  1. These results indicate that BARF1 blockade of CSF-1 signaling is an important immune evasion strategy for efficient acute EBV infection and a significant determinant for virus setpoint during persistent EBV infection.

Zebrafish Colony Stimulating Factor 1 (Macrophage) (CSF1) interaction partners

  1. the complete sequencing of M-CSF (show CSF1R Proteins) genes, gene organizaztion,splice varaiants, gene expression, and M-CSF (show CSF1R Proteins) role in the immune system

Human Colony Stimulating Factor 1 (Macrophage) (CSF1) interaction partners

  1. M-CSF has been shown to be comparable to CA15-3 and VEGF, specificity, and AUC values only in stages III and IV of BC.

  2. M-CSF macrophage conversion into foam cells reduces their proinflammatory responses to classical M1-polarizing activation

  3. This can be achieved by either blocking the EGF (show EGF Proteins) or CSF-1 receptors or supressing the EGF (show EGF Proteins) or CSF-1 signal.

  4. findings demonstrated that M-CSF binds to IL-34 (show IL34 Proteins); molecular docking studies predicted the formation of a heteromeric M-CSF/IL-34 (show IL34 Proteins) cytokine

  5. RGC-32 (show C13orf15 Proteins) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4 (show IL4 Proteins).

  6. Data show crystal structures of CSF1-CSF1R (show CSF1R Proteins) ternary complexes, and propose a mechanism for their cooperative action that relies on the adoption by dimeric CSF-1 of an active conformational state and homotypic receptor interactions.

  7. In patients with CLE (show EIF2B5 Proteins), 100 and 150 mg PD-0360324 (monoclonal antibody against MCSF) every 2 weeks for 3 months suppressed a subset of circulating monocytes.

  8. peripheral nerve injury induced de novo expression of colony-stimulating factor 1 (CSF1) in injured sensory neurons. CSF1 was transported to the spinal cord, where it targeted the microglial CSF1 receptor (CSF1R (show CSF1R Proteins)).

  9. These findings highlight an essential role for PRKAA1 (show PRKAA1 Proteins)-mediated autophagy during differentiation of human monocytes.

  10. These findings suggest a high usefulness of M-CSF in diagnosing the serous sub-type of epithelial ovarian cancer and in discriminating between cancer and non-carcinoma lesions

Mouse (Murine) Colony Stimulating Factor 1 (Macrophage) (CSF1) interaction partners

  1. study shows that PLCgamma1 (show PLCG1 Proteins) controls osteoclast numbers via a CSF-1-dependent DAG/beta-catenin (show CTNNB1 Proteins)/cyclinD1 pathway.

  2. study concludes that Langerhans cells require IL-34 (show IL34 Proteins) when residing in fully differentiated and anatomically intact skin epidermis, but rely on neutrophil-derived CSF1 during inflamma

  3. Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF (show CSF2 Proteins)) and Macrophage Colony Stimulating Factor (show CSF2 Proteins) (M-CSF (show CSF1R Proteins)) Grown Macrophages Derived from Murine Bone Marrow Cells

  4. Hematopoietic cells can be induced by M-CSF (show CSF1R Proteins) to dedifferentiate to multipotent stem cells.

  5. M-CSF (show CSF1R Proteins) promotes macrophagic over granulocytic differentiation by inducing ERK (show EPHB2 Proteins) activation but also PKCd (show PKCd Proteins) expression, which in turn, down-regulates Fli-1 (show FLI1 Proteins) expression and prevents granulocytic differentiation.

  6. Results identify CSF-1-activated macrophages as crucial mediators of detrimental Schwann cell dedifferentiation in Cx32 (show GJB1 Proteins)-deficient mice

  7. Ceramide production in M-CSF (show CSF1R Proteins)-deprived macrophages arises from a combination of ASMase (show SMPD1 Proteins) activity and de novo synthesis.

  8. CSF-1 did not rescue the growth and lung defects associated with hyperoxia in this model; however, an increase in CSF-1R (show CSF1R Proteins)+ macrophages was not associated with an exacerbation of lung injury.

  9. CSF-1 neutralization led to a relatively uniform reduction in all inflammatory cell populations; GM-CSF (show CSF2 Proteins) neutralization resulted in the preferential loss among the monocyte/macrophage populations.

  10. The results of this study indicated that the CSF1 overexpression observed in CNS pathologies likely has pleiotropic influences on microglia.

CSF1 Protein Profile

Protein Summary

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with CSF1

  • colony stimulating factor 1 (macrophage) (CSF1)
  • colony stimulating factor 1a (macrophage) (csf1a)
  • colony stimulating factor 1 (macrophage) (Csf1)
  • macrophage colony stimulating factor alpha (MCSF ALPHA)
  • C87615 protein
  • CSF-1 protein
  • CSF1 protein
  • csf1-1 protein
  • Csfm protein
  • MCSF protein
  • op protein
  • zgc:172186 protein

Protein level used designations for CSF1

macrophage colony-stimulating factor 1 , colony stimulating factor 1 (macrophage) , mcsf1 , macrophage colony-stimulating factor 1-like , colony-stimulating factor 1 , lanimostim , CSF-1 , MCSF , osteopetrosis

281094 Bos taurus
457127 Pan troglodytes
611795 Canis lupus familiaris
702532 Macaca mulatta
100004617 Danio rerio
100452144 Pongo abelii
100499187 Taeniopygia guttata
1435 Homo sapiens
78965 Rattus norvegicus
12977 Mus musculus
100732898 Cavia porcellus
396599 Sus scrofa
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