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anti-Human CSF1R antibody for Functional Studies

Recommended CSF1R Antibody (supplied by: Log in to see )

Antigen
Colony Stimulating Factor 1 Receptor (CSF1R) Antibodies
  • AI323359
  • c-fms
  • C-FMS
  • CD115
  • CSF-1-R
  • CSF-1R
  • CSF1
  • csf1r
  • Csfmr
  • CSFR
  • Fim-2
  • FIM2
  • fms
  • FMS
  • Fms
  • HDLS
  • M-CSF
  • M-CSF-R
  • M-CSFR
  • MGC89146
  • mrfms
  • panther
Reactivity
Human
283
187
59
21
12
9
7
4
4
4
2
2
2
2
1
Host
Rat
231
122
49
28
3
Clonality
Monoclonal
Conjugate
This CSF1R antibody is un-conjugated
33
28
22
18
17
9
8
6
5
5
4
4
4
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
280
205
164
123
42
38
25
19
18
15
12
11
9
7
4
3
3
2
2
2
1
Supplier
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Catalog No. ABIN180375
$ 496.65
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008758766 ABIN2135849 Func FACS IHC WB Rat IgG1 Log in to see 12-3A3-1B10

Similar anti-CSF1R Antibodies

Application / Reactivity Human
Blocking Reagent (BR) 1 Antibodies
ELISA 158 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 81 Antibodies
Functional Studies (Func) 2 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 14 Antibodies
Immunofluorescence (IF) 37 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 84 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 41 Antibodies
Immunoprecipitation (IP) 16 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Neutralization (Neut) 2 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 210 Antibodies

General

Antigen Colony Stimulating Factor 1 Receptor (CSF1R) Antibodies
Reactivity Human
(283), (187), (59), (21), (12), (9), (7), (4), (4), (4), (2), (2), (2), (2), (1)
Host Rat
(231), (122), (49), (28), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CSF1R antibody is un-conjugated
(33), (28), (22), (18), (17), (9), (8), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
(280), (205), (164), (123), (42), (38), (25), (19), (18), (15), (12), (11), (9), (7), (4), (3), (3), (2), (2), (2), (1)
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Product Details anti-CSF1R Antibody

Target Details CSF1R Application Details Handling Images
Specificity Binds to epitope aa 349-512.
Cellular Localization:Cell membrane. Mol. Wt. of Antigen: 130-150 kDa Does not react with Mouse and Cat.
Characteristics Synonyms: CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1receptor
Purification IgG purified from ascites fluid by ammonium sulfate precipitation
Immunogen v-ras-transformed rat NRK cells expressing transduced human CSF-1R
Clone 2-4A5-4
Isotype IgG1

Target Details CSF1R

Product Details anti-CSF1R Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD115 (CSF1R Antibody Abstract)
Background CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (M-CSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
Gene ID 1436
UniProt P07333
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-CSF1R Antibody Target Details CSF1R Handling Images back to top
Application Notes Blocks Ligand Binding, Blocks Ligand-dependent Proliferation and inhibitsCSF-1-independend Growth of Cells Expressing Mutant CSF-1R (see Ref.2, use azide freeantibody ABIN180374). Also useful for Immunofluorescence (see Ref.1) andImmunohistology (Acetone-fixed frozen sections). Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CSF1R Antibody Target Details CSF1R Application Details Images back to top
Concentration 0.2 mg/mL
Buffer 10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 2-8 °C for up to one month or in aliquots at -20 °C for longer. Avoid repeated freezethaw cycles!
Shelf life: one year from despatch.
Expiry Date 12 months