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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Immunofluorescence (fixed cells) (IF/ICC)||2 Antibodies||1 Antibodies|
|Cytometry by Time of Flight (CyTOF)||2 Antibodies|
|Western Blotting (WB)||216 Antibodies||114 Antibodies||53 Antibodies|
|Proximity Ligation Assay (PLA)||2 Antibodies|
|Neutralization (Neut)||2 Antibodies||3 Antibodies|
|Mass Cytometry (CyTOF)||2 Antibodies|
|Intracellular Flow Cytometry (ICFC)||2 Antibodies||1 Antibodies|
|Immunoprecipitation (IP)||4 Antibodies||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||47 Antibodies||18 Antibodies||14 Antibodies|
|Immunohistochemistry (IHC)||91 Antibodies||60 Antibodies||15 Antibodies|
|Antigen||Colony Stimulating Factor 1 Receptor (CSF1R) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CSF1R antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Product Details anti-CSF1R AntibodyTarget Details CSF1R Application Details Handling Images
|Specificity||This antibody detects endogenous levels of CSFR protein.|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purification||Affinity Chromatography using epitope-specific immunogen.|
Target Details CSF1RProduct Details anti-CSF1R Antibody Application Details Handling Images back to top
|Alternative Name||CD115 (CSF1R Antibody Abstract)|
|Background||This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms|
|Molecular Weight||approx. 92, 108 kDa|
|Research Area||CD Antigens, Surface Receptors of Immune Cells|
|Pathways||RTK Signaling, Inositol Metabolic Process|
Application DetailsProduct Details anti-CSF1R Antibody Target Details CSF1R Handling Images back to top
Immunoflourescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-CSF1R Antibody Target Details CSF1R Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-CSF1R Antibody Target Details CSF1R Application Details Handling back to top