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anti-Rat (Rattus) CSF1R antibody for Functional Studies

Recommended CSF1R Antibody (supplied by: Log in to see )

Antigen
Colony Stimulating Factor 1 Receptor (CSF1R) Antibodies
  • AI323359
  • c-fms
  • C-FMS
  • CD115
  • CSF-1-R
  • CSF-1R
  • CSF1
  • csf1r
  • Csfmr
  • CSFR
  • Fim-2
  • FIM2
  • fms
  • FMS
  • Fms
  • HDLS
  • M-CSF
  • M-CSF-R
  • M-CSFR
  • MGC89146
  • mrfms
  • panther
Reactivity
Mouse (Murine), Rat (Rattus)
284
186
58
21
12
9
7
4
4
4
2
2
2
2
1
Host
Rat
231
122
49
28
3
Clonality
Monoclonal
Conjugate
This CSF1R antibody is un-conjugated
33
28
22
18
17
9
8
6
5
5
4
4
4
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS)
280
205
163
123
42
39
25
20
18
15
12
11
9
7
4
3
3
2
2
2
1
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Catalog No. ABIN317381
$ 1,303.50
Plus shipping costs $45.00

Top referenced anti-CSF1R antibody for Functional Studies

Similar anti-CSF1R Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 24 Antibodies 57 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Flow Cytometry (FACS) 3 Antibodies 82 Antibodies
Functional Studies (Func) 1 Antibodies 24 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 14 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Western Blotting (WB) 37 Antibodies
ELISA (Detection) 2 Antibodies

General

Antigen Colony Stimulating Factor 1 Receptor (CSF1R) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(284), (186), (58), (21), (12), (9), (7), (4), (4), (4), (2), (2), (2), (2), (1)
Host Rat
(231), (122), (49), (28), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CSF1R antibody is un-conjugated
(33), (28), (22), (18), (17), (9), (8), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS)
(280), (205), (163), (123), (42), (39), (25), (20), (18), (15), (12), (11), (9), (7), (4), (3), (3), (2), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-CSF1R Antibody

Target Details CSF1R Application Details Handling References for anti-CSF1R Antibody (ABIN317381) Images
Specificity This antibody recognizes the Murine CD115 cell surface antigen, also known as the M-CSF receptor and as c-fms. This antibody has been shown to inhibit in vitro colony formation in response to M-CSF in both rats and mice.
Characteristics Synonyms: CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1receptor
Purification Purified IgG prepared by ion exchange chromatography
Immunogen RAW 264 cells. Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653myeloma cell line.
Clone 604B5 2E11
Isotype IgG1

Target Details CSF1R

Product Details anti-CSF1R Antibody Application Details Handling References for anti-CSF1R Antibody (ABIN317381) Images back to top
Antigen
Alternative Name CD115 (CSF1R Antibody Abstract)
Background This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
Gene ID 12978
UniProt P09581
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-CSF1R Antibody Target Details CSF1R Handling References for anti-CSF1R Antibody (ABIN317381) Images back to top
Application Notes Functional Assays. Flow Cytometry: Use 10 μL of 1/10-1/100 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CSF1R Antibody Target Details CSF1R Application Details References for anti-CSF1R Antibody (ABIN317381) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, None, None
Preservative Without preservative
Storage -20 °C
Storage Comment Store the antibody undiluted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-CSF1R Antibody (ABIN317381)

Product Details anti-CSF1R Antibody Target Details CSF1R Application Details Handling Images back to top
Background publications

MacDonald, Rowe, Bofinger, Thomas, Sasmono, Hume, Hill: "The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 3, pp. 1399-405, 2005

Shadduck, Fischer, DePasquale, Gilmore: "Paradoxical stimulation of normal and leukemic rat hematopoiesis by monoclonal antibody to CSF-1 receptor." in: Experimental hematology, Vol. 24, Issue 2, pp. 314-7, 1996

Gilmore, Shadduck: "Inhibition of day-12 spleen colony-forming units by a monoclonal antibody to the murine macrophage/monocyte colony-stimulating factor receptor." in: Blood, Vol. 85, Issue 10, pp. 2731-4, 1995