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Browse our anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antibodies

Full name:
anti-Discoidin Domain Receptor tyrosine Kinase 1 Antibodies (DDR1)
On www.antibodies-online.com are 146 Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antibodies from 18 different suppliers available. Additionally we are shipping Discoidin Domain Receptor tyrosine Kinase 1 Proteins (19) and Discoidin Domain Receptor tyrosine Kinase 1 Kits (10) and many more products for this protein. A total of 189 Discoidin Domain Receptor tyrosine Kinase 1 products are currently listed.
Synonyms:
6030432F18, AI323681, CAK, CD167, CD167a, CG9488, CG9490, CG11573, CG13984, CG13985, CG33531, CT33540, DDR, Dmel\\CG33531, Dmel_CG13984, Drd1, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, PTK3D, RTK6, TRKE
list all antibodies Gene Name GeneID UniProt
DDR1 12305 Q03146
DDR1 780 Q08345
DDR1 25678  

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All available anti-Discoidin Domain Receptor tyrosine Kinase 1 Antibodies

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Top referenced anti-Discoidin Domain Receptor tyrosine Kinase 1 Antibodies

  1. Human Polyclonal DDR1 Primary Antibody for FACS, IHC (p) - ABIN392014 : Vogel, Gish, Alves, Pawson: The discoidin domain receptor tyrosine kinases are activated by collagen. in Molecular cell 1998 (PubMed)
    Show all 3 references for ABIN392014

  2. Human Monoclonal DDR1 Primary Antibody for ELISA, WB - ABIN969082 : Foehr, Tatavos, Tanabe, Raffioni, Goetz, Dimarco, De Luca, Bradshaw: Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000 (PubMed)
    Show all 3 references for ABIN969082

  3. Human Monoclonal DDR1 Primary Antibody for WB - ABIN2869332 : Mohan, Mohan, Wilson: Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea. in Experimental eye research 2001 (PubMed)
    Show all 3 references for ABIN2869332

  4. Human Polyclonal DDR1 Primary Antibody for IHC (p), WB - ABIN392016 : Valent, Meddeb, Danglot, Duverger, Nguyen, Bernheim: Assignment of the NTRK4 (trkE) gene to chromosome 6p21. in Human genetics 1996 (PubMed)
    Show all 3 references for ABIN392016

  5. Human Polyclonal DDR1 Primary Antibody for FACS, IF - ABIN391458 : Johnson, Edman, Rutter: A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 2 references for ABIN391458

  6. Human Polyclonal DDR1 Primary Antibody for ELISA, WB - ABIN560139 : Turashvili, Bouchal, Baumforth, Wei, Dziechciarkova, Ehrmann, Klein, Fridman, Skarda, Srovnal, Hajduch, Murray, Kolar: Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. in BMC cancer 2007 (PubMed)

More Antibodies against Discoidin Domain Receptor tyrosine Kinase 1 Interaction Partners

Mouse (Murine) Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) interaction partners

  1. DDR-1 interacts with the TGF-beta (show TGFB1 Antibodies) pathway to restrict calcifying extracellular vesicle-mediated mineralization and fibrosis by smooth muscle cells.

  2. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (show ITGA2 Antibodies) DDR1-mediated ERK (show EPHB2 Antibodies) activation.

  3. DDR1 malfunction causes outer hair cells deformation and the separation of the lateral wall, the location of the cellular motor responsible for the electromotile property, explicitly in those regions showing DDR1 and NM-IIA co-localization.

  4. the collagen receptors DDR1 and integrin a2b1 contribute to regulate GBM-maturation and to control matrix accumulation.

  5. Extensive co-localization and relationship of Jag1 (show JAG1 Antibodies) and Ddr1 in bile ducts and blood vessels in postnatal liver.

  6. Genetic inhibition of discoidin domain receptor 1 protects mice against crescentic glomerulonephritis.

  7. Data identifyies Syk (show SYK Antibodies) as a potent inhibitor of epithelial migration and describes a first functional consequence of the interaction with the collagen receptor (show ITGA2 Antibodies) DDR1.

  8. Results show that DDR1 promotes cell-cell adhesion and differentiation through stabilization of E-cadherin (show CDH1 Antibodies), which is mediated by Cdc42 (show CDC42 Antibodies) inactivation.

  9. Collagen I stimulates the self-renewal of embryonic stem cells mediated by Bmi-1 (show BMI1 Antibodies) through alpha2beta1 integrin-dependent ILK (show ILK Antibodies), Notch (show NOTCH1 Antibodies), Gli-1 (show GLI1 Antibodies), and DDR1-dependent Ras, PI3K/Akt (show AKT1 Antibodies), and ERK (show EPHB2 Antibodies).

  10. Loss of Discoidin domain receptor 1 is associated with inflammation and fibrosis in obstructive nephropathy

Human Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) interaction partners

  1. Knockdown DDR1 reversed the effects of Galpha13 (show GNA13 Antibodies) knockdown on cell-cell adhesion and proteolytic invasion in three-dimensional collagen.

  2. Data suggest SCl2 (Streptococcus pyogenes) binds to DDR (DDR1, DDR2 (show DDR2 Antibodies)) ectodomain w/o stimulating receptor signaling; here, protein engineering was used to construct SCl (show KRT7 Antibodies)-like proteins that inhibit collagen-DDR interactions and macrophage migration.

  3. DDR1 is a key modulator of RIT (show RIT1 Antibodies) activity.

  4. DDR1 expression is a prognostic indicator in pancreatic ductal carcinoma.

  5. alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor (show ITGA2 Antibodies) DDR1-mediated ERK (show EPHB2 Antibodies) activation.

  6. Hypoxia can increase DDR1 expression in pituitary adenoma cells, leading to improved MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies) secretion, and promoting pituitary adenoma cell proliferation and invasion.

  7. suggest that DDR1 suppression may enhance adipose-derived stem cell chondrogenesis by enhancing the expression of chondrogenic genes and cartilaginous matrix deposition.

  8. MT1-MMP (show MMP14 Antibodies)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells

  9. Defective Ca(2 (show CA2 Antibodies)+) binding in a conserved binding site causes incomplete N-glycan processing and endoplasmic reticulum trapping of DDR1 and DDR2 (show DDR2 Antibodies) receptors.

  10. A DDR1(Low)/DDR2 (show DDR2 Antibodies)(High) protein profile is associated with TNBC and may identify invasive carcinomas with worse prognosis.

Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antigen Profile

Antigen Summary

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with Discoidin Domain Receptor tyrosine Kinase 1 (DDR1)

  • Discoidin domain receptor (Ddr) antibody
  • discoidin domain receptor family, member 1 (Ddr1) antibody
  • discoidin domain receptor tyrosine kinase 1 (DDR1) antibody
  • discoidin domain receptor tyrosine kinase 1 (Ddr1) antibody
  • 6030432F18 antibody
  • AI323681 antibody
  • CAK antibody
  • CD167 antibody
  • CD167a antibody
  • CG9488 antibody
  • CG9490 antibody
  • CG11573 antibody
  • CG13984 antibody
  • CG13985 antibody
  • CG33531 antibody
  • CT33540 antibody
  • DDR antibody
  • Dmel\\CG33531 antibody
  • Dmel_CG13984 antibody
  • Drd1 antibody
  • EDDR1 antibody
  • HGK2 antibody
  • MCK10 antibody
  • NEP antibody
  • NTRK4 antibody
  • PTK3 antibody
  • PTK3A antibody
  • PTK3D antibody
  • RTK6 antibody
  • TRKE antibody

Protein level used designations for DDR1

CG33531-PA , CG33531-PB , Ddr-PA , Ddr-PB , discoidin domain receptor , CD167 antigen-like family member A , cell adhesion kinase , discoidin receptor tyrosine kinase , epithelial discoidin domain receptor 1 , epithelial discoidin domain-containing receptor 1 , protein-tyrosine kinase MPK-6 , tyrosine kinase DDR , tyrosine-protein kinase CAK , PTK3A protein tyrosine kinase 3A , mammary carcinoma kinase 10 , neuroepithelial tyrosine kinase , neurotrophic tyrosine kinase, receptor, type 4 , protein-tyrosine kinase RTK-6 , discoidin domain receptor family, member 1 , neurotrophic tyrosine kinase receptor type 4 , protein-tyrosine kinase 3 , protein-tyrosine kinase PTK-3

GENE ID SPECIES
3346209 Drosophila melanogaster
12305 Mus musculus
780 Homo sapiens
25678 Rattus norvegicus
100144462 Sus scrofa
462548 Pan troglodytes
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