anti-Human DDR1 antibody for Immunoprecipitation

Recommended DDR1 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antibodies
  • CG11573
  • CG13984
  • CG13985
  • CG33531
  • CG9488
  • CG9490
  • CT33540
  • DDR
  • Dmel\\CG33531
  • Dmel_CG13984
  • 6030432F18
  • AI323681
  • CD167a
  • Cak
  • Nep
  • PTK3A
  • CAK
  • CD167
  • EDDR1
  • HGK2
  • MCK10
  • NEP
  • NTRK4
  • PTK3
  • RTK6
  • TRKE
  • Drd1
  • PTK3D
  • Discoidin domain receptor
  • discoidin domain receptor family, member 1
  • discoidin domain receptor tyrosine kinase 1
  • Ddr
  • Ddr1
  • DDR1
Epitope
AA 1-416
26
23
16
15
13
8
8
6
6
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
168
53
53
10
6
4
4
3
3
2
2
2
2
Host
Rabbit
138
30
1
Clonality
Monoclonal
Conjugate
This DDR1 antibody is un-conjugated
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
105
63
45
40
26
14
6
4
1
1
1
Supplier
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Catalog No. ABIN1997363
$ 273.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
23.836172 ABIN1997367 IP ELISA WB Rabbit IgG AA 1-416 Log in to see Polyclonal
1 ABIN1831311 ICC IP WB Rabbit IgG Pro600 Log in to see 11C1024
1 ABIN2626012 IP WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN2251793 IF IP WB Rabbit IgG Log in to see 11C1024

General

Antigen Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) Antibodies
Epitope AA 1-416
(26), (23), (16), (15), (13), (8), (8), (6), (6), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(168), (53), (53), (10), (6), (4), (4), (3), (3), (2), (2), (2), (2)
Host Rabbit
(138), (30), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This DDR1 antibody is un-conjugated
(4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(105), (63), (45), (40), (26), (14), (6), (4), (1), (1), (1)
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Product Details anti-DDR1 Antibody

Target Details DDR1 Application Details Handling Images
Specificity Human DDR1 / CD167
Has cross-reactivity in ELISA with
Human DDR2
Cross-Reactivity Human
Characteristics This antibody was obtained from a rabbit immunized with purified, recombinant Human DDR1 / CD167 (rh DDR1 / CD167, ABIN2003316 NP_001945.3, Met 1-Thr 416,.
Sterility 0.2 μm filtered
Immunogen Recombinant Human DDR1 / CD167 protein (ABIN2003316)
Clone 203
Isotype IgG

Target Details DDR1

Product Details anti-DDR1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name DDR1 (DDR1 Antibody Abstract)
Background Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracellular domain homologous to Dictyostellium discoideum protein discoidin 1. Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Expression of DDR1/MCK10/CD167 is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. DDR1/MCK10/CD167 plays an important role in regulating attachment to collagen, chemotaxis, proliferation, and MMP production in smooth muscle cells. DDR1 functions in a feedforward loop to increase p53 levels and at least some of its effectors. Inhibition of DDR1 function resulted in strikingly increased apoptosis of wild-type p53-containing cells in response to genotoxic stress through a caspase-dependent pathway.
NCBI Accession NP_001945.3
Pathways RTK Signaling, Smooth Muscle Cell Migration

Application Details

Product Details anti-DDR1 Antibody Target Details DDR1 Handling Images back to top
Application Notes WB: 5-10 μg/mL
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human DDR1. The detection limit for Human DDR1 is approximately 0.00245 ng/well.
IP: 1-4 μg/mg of lysate
Restrictions For Research Use only

Handling

Product Details anti-DDR1 Antibody Target Details DDR1 Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

Images

Product Details anti-DDR1 Antibody Target Details DDR1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 1-416) antibody (ABIN1997363) anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 1-416) antibody
Immunoprecipitation (IP) image for anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 1-416) antibody (ABIN1997363) anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 1-416) antibody (Image 2)