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anti-Human DDR2 antibody for Immunohistochemistry

Recommended DDR2 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
  • AW495251
  • DDR2
  • ddr2
  • MIG20a
  • NTRKR3
  • Ntrkr3
  • si:ch211-193c2.1
  • TKT
  • Tyro10
  • tyro10
  • TYRO10
Reactivity
Human
73
31
4
1
Host
Mouse
68
28
Clonality
Monoclonal
Conjugate
This DDR2 antibody is un-conjugated
4
4
4
4
4
4
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
77
52
34
14
14
10
3
2
1
1
Supplier
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Catalog No. ABIN969083
$ 442.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.22874774 ABIN2855418 FACS IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal
0.22874774 ABIN2469944 IF IHC ELISA WB Mouse IgG2a truncated Log in to see
0.22874774 ABIN2158508 FACS IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
0.22874774 ABIN2432083 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.22874774 ABIN2426677 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.22874774 ABIN1843313 ICC IF IHC ELISA WB Mouse IgG2a Log in to see
0.0011326512 ABIN2464044 IHC ELISA WB Mouse IgG2a truncated Log in to see 3B11E4
0.0011326512 ABIN449954 ICC IF IHC (p) IHC ELISA WB Mouse IgG2a Log in to see 3B11E4
0.0011326512 ABIN2869259 IF IHC WB Mouse IgG2a Log in to see
0.0011326512 ABIN2138961 IF IHC ELISA WB Mouse IgG2a Log in to see 3B11E4
0.0011326512 ABIN2251797 IHC ELISA WB Mouse IgG2a Log in to see 13B220
0.0011326512 ABIN1582772 IF IHC WB Mouse IgG2a Log in to see 3B11E4
0.0011326512 ABIN4304587 IHC IHC (p) WB Rabbit Log in to see Polyclonal
0.0011326512 ABIN4304588 FACS IHC IHC (p) WB Rabbit Log in to see Polyclonal
0.0011326512 ABIN2251814 IF IHC ELISA WB Mouse IgG2a Log in to see
0.0011326512 ABIN3030741 FACS IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
0.0011326512 ABIN2764668 IHC (p) IHC ELISA WB Mouse IgG2a Log in to see
0.0011326512 ABIN1576037 IF IHC ELISA WB Mouse Log in to see
0.0011326512 ABIN2793177 FACS IHC WB Rabbit Ig Fraction Log in to see Polyclonal

Top referenced anti-DDR2 antibody for Immunohistochemistry

Similar anti-DDR2 Antibodies

Application / Reactivity Human
ELISA 38 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 14 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 20 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 Antibodies
Western Blotting (WB) 60 Antibodies

General

Antigen Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
Reactivity Human
(73), (31), (4), (1)
Host Mouse
(68), (28)
Clonality (Clone)
Monoclonal   ( )
Conjugate This DDR2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(77), (52), (34), (14), (14), (10), (3), (2), (1), (1)
Pubmed 3 references available
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Product Details anti-DDR2 Antibody

Target Details DDR2 Application Details Handling References for anti-DDR2 Antibody (ABIN969083) Images
Purification Ascites
Immunogen Purified recombinant fragment of human DDR2 expressed in E. coli.
Clone 3B11E4
Isotype IgG2a

Target Details DDR2

Product Details anti-DDR2 Antibody Application Details Handling References for anti-DDR2 Antibody (ABIN969083) Images back to top
Antigen
Alternative Name DDR2 (DDR2 Antibody Abstract)
Background DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/ threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Gene ID 4921
HGNC 4921
Research Area Cardiovascular, Cardiogenesis
Pathways RTK Signaling

Application Details

Product Details anti-DDR2 Antibody Target Details DDR2 Handling References for anti-DDR2 Antibody (ABIN969083) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details References for anti-DDR2 Antibody (ABIN969083) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-DDR2 Antibody (ABIN969083)

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling Images back to top
Product cited in:

Leitinger, Kwan: "The discoidin domain receptor DDR2 is a receptor for type X collagen." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 25, Issue 6, pp. 355-64, 2006

Shyu, Chao, Wang, Kuan: "Regulation of discoidin domain receptor 2 by cyclic mechanical stretch in cultured rat vascular smooth muscle cells." in: Hypertension, Vol. 46, Issue 3, pp. 614-21, 2005

Neale, Kenny, Gershwin: "Cloning and sequencing of protein kinase cDNA from harbor seal (Phoca vitulina) lymphocytes." in: Clinical & developmental immunology, Vol. 11, Issue 2, pp. 157-63, 2004

Images

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling References for anti-DDR2 Antibody (ABIN969083) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-DDR2 antibody (Discoidin Domain Receptor tyrosine Kinase 2) (ABIN969083) Figure 1: Confocal immunofluorescence analysis of A549 cells using DDR2 mouse mAb (gr...
Immunohistochemistry (IHC) image for anti-DDR2 antibody (Discoidin Domain Receptor tyrosine Kinase 2) (ABIN969083) Figure 2: Immunohistochemical analysis of paraffin-embedded human skeletal musle tiss...
Western Blotting (WB) image for anti-DDR2 antibody (Discoidin Domain Receptor tyrosine Kinase 2) (ABIN969083) Figure 3: Western blot analysis using DDR2 mouse mAb against truncated DDR2 recombina...