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anti-Mouse (Murine) DDR2 antibody for ELISA

Recommended DDR2 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
  • AW495251
  • DDR2
  • ddr2
  • MIG20a
  • NTRKR3
  • Ntrkr3
  • si:ch211-193c2.1
  • TKT
  • Tyro10
  • tyro10
  • TYRO10
Epitope
AA 1-399
19
15
13
7
6
4
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
74
30
4
1
Host
Rabbit
67
29
Clonality
Polyclonal
Conjugate
This DDR2 antibody is un-conjugated
4
4
4
4
4
4
1
1
1
1
1
1
1
Minimum Detection Limit
0.039 ng/well
Application
ELISA
78
52
35
14
14
10
3
3
1
1
Supplier
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Catalog No. ABIN2001101
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0012121403 ABIN2001099 ELISA Rabbit IgG AA 1-399 Log in to see Polyclonal 2
0.0012121403 ABIN1975963 IHC ELISA WB PE Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN1964949 IHC ELISA WB APC Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN1962572 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN1971363 IHC ELISA WB FITC Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN1583816 ELISA WB Rabbit Middle Region Log in to see Polyclonal
0.0012121403 ABIN1969617 IHC ELISA WB Biotin Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN1972984 IHC ELISA WB HRP Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN2251799 IHC ELISA WB APC Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN2251801 IHC ELISA WB FITC Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN2251807 IHC ELISA WB HRP Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN2251808 IHC ELISA WB PE Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN2432083 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.0012121403 ABIN2426677 IHC ELISA Rabbit IgG Log in to see Polyclonal
0.0012121403 ABIN2251798 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG C-Term, AA 815-843 Log in to see Polyclonal
0.0012121403 ABIN3028617 IHC ELISA WB Rabbit Ig Fraction AA 816-843 Log in to see Polyclonal
0.0012121403 ABIN3030737 ELISA WB Rabbit Ig Fraction Log in to see Polyclonal

Similar anti-DDR2 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 18 Antibodies
Flow Cytometry (FACS) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 21 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 7 Antibodies
Western Blotting (WB) 26 Antibodies

General

Antigen Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) Antibodies
Epitope AA 1-399
(19), (15), (13), (7), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(74), (30), (4), (1)
Host Rabbit
(67), (29)
Clonality
Polyclonal
Conjugate This DDR2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1)
Minimum Detection Limit 0.039 ng/well
Application ELISA
(78), (52), (35), (14), (14), (10), (3), (3), (1), (1)
Pubmed 2 references available
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Product Details anti-DDR2 Antibody

Target Details DDR2 Application Details Handling References for anti-DDR2 Antibody (ABIN2001101) Images
Specificity Mouse DDR2
Characteristics Produced in rabbits immunized with purified, recombinant Mouse DDR2 (rM DDR2, NP_072075.2, Met 1-Arg 399). DDR2 specific IgG was purified by Mouse DDR2 affinity chromatography.
Purification Affinity Purified
Sterility 0.2 μm filtered
Isotype IgG

Target Details DDR2

Product Details anti-DDR2 Antibody Application Details Handling References for anti-DDR2 Antibody (ABIN2001101) Images back to top
Antigen
Alternative Name DDR2 (DDR2 Antibody Abstract)
Background Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2, up-regulates matrix metallloproteinase 1 (MMP-1) and MMP-2 expression in cellular matrix. DDR2/CD167b was found to recognise the triple-helical region of collagen X as well as the NC1 domain. Binding to the collagenous region was dependent on the triple-helical conformation. DDR2/CD167b autophosphorylation was induced by the collagen X triple- helical region but not the NC1 domain, indicating that the triple-helical region of collagen X contains a specific DDR2 binding site that is capable of receptor activation. DDR2/CD167b is induced during stellate cell activation and implicate the phosphorylated receptor as a mediator of MMP-2 release and growth stimulation in response to type I collagen. Moreover, type I collagen-dependent upregulation of DDR2/CD167b expression establishes a positive feedback loop in activated stellate cells, leading to further proliferation and enhanced invasive activity.
NCBI Accession NP_072075.2
Research Area Cardiovascular, Cardiogenesis
Pathways RTK Signaling

Application Details

Product Details anti-DDR2 Antibody Target Details DDR2 Handling References for anti-DDR2 Antibody (ABIN2001101) Images back to top
Application Notes ELISA ELISA: 0.1-0.2 μg/mL This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect.
Restrictions For Research Use only

Handling

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details References for anti-DDR2 Antibody (ABIN2001101) Images back to top
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

References for anti-DDR2 Antibody (ABIN2001101)

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling Images back to top
Background publications

Zhang, Ding, Zhang, Su, Li, Liu, Ma, Yao: "Expression of discoidin domain receptor 2 (DDR2) extracellular domain in pichia pastoris and functional analysis in synovial fibroblasts and NIT3T3 cells." in: Molecular and cellular biochemistry, Vol. 290, Issue 1-2, pp. 43-53, 2006

Leitinger, Steplewski, Fertala: "The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2." in: Journal of molecular biology, Vol. 344, Issue 4, pp. 993-1003, 2004

Images

Product Details anti-DDR2 Antibody Target Details DDR2 Application Details Handling References for anti-DDR2 Antibody (ABIN2001101) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DDR2 antibody (Discoidin Domain Receptor tyrosine Kinase 2) (AA 1-399) (ABIN2001101) anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 1-399) antibody
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-DDR2 antibody (Discoidin Domain Receptor tyrosine Kinase 2) (AA 1-399) (ABIN2001101) anti-Discoidin Domain Receptor tyrosine Kinase 2 (DDR2) (AA 1-399) antibody (Image 2)