anti-Human EPH Receptor A2 antibody for Cell-ELISA

Recommended EPH Receptor A2 Antibody (supplied by: Log in to see )

Antigen
EPH Receptor A2 (EPHA2) Antibodies
  • EPHA2
  • epha2
  • MGC89505
  • ARCC2
  • CTPA
  • CTPP1
  • CTRCT6
  • ECK
  • AW545284
  • Eck
  • Myk2
  • Sek-2
  • Sek2
  • EPH receptor A2
  • EphA2
  • epoxide hydrolase
  • Eph receptor A2
  • EPHA2
  • epha2
  • ephA2
  • Epha2
Reactivity
Human
298
181
56
22
14
10
8
7
4
4
2
2
2
2
1
Host
Mouse
218
102
45
4
1
1
Clonality
Monoclonal
Conjugate
This EPH Receptor A2 antibody is un-conjugated
21
15
14
13
13
11
9
8
8
8
8
8
8
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
Application
Cell-ELISA (cELISA), Flow Cytometry (FACS), Immunofluorescence (IF)
252
164
119
68
57
27
17
10
8
8
6
4
4
2
2
1
1
Supplier
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Catalog No. ABIN179724
$ 386.93
Plus shipping costs $45.00

General

Antigen EPH Receptor A2 (EPHA2) Antibodies
Reactivity Human
(298), (181), (56), (22), (14), (10), (8), (7), (4), (4), (2), (2), (2), (2), (1)
Host Mouse
(218), (102), (45), (4), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EPH Receptor A2 antibody is un-conjugated
(21), (15), (14), (13), (13), (11), (9), (8), (8), (8), (8), (8), (8), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2)
Application Cell-ELISA (cELISA), Flow Cytometry (FACS), Immunofluorescence (IF)
(252), (164), (119), (68), (57), (27), (17), (10), (8), (8), (6), (4), (4), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-EPH Receptor A2 Antibody

Target Details EPH Receptor A2 Application Details Handling References for anti-EPH Receptor A2 antibody (ABIN179724) Images
Specificity Anti-human EphA2
Purification Protein G
Immunogen genetic immunisation with cDNA encoding human EphA2
Clone Kalpha-5H5
Isotype IgG1

Target Details EPH Receptor A2

Product Details anti-EPH Receptor A2 Antibody Application Details Handling References for anti-EPH Receptor A2 antibody (ABIN179724) Images back to top
Antigen
Alternative Name EPHA2 (EPHA2 Antibody Abstract)
Background EphA2 (Ephrin receptor tyrosine kinase A2) belongs to the Ephrin tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells. Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis. The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represent an attractive potential target for drug design.
UniProt P29317
Pathways RTK Signaling

Application Details

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Handling References for anti-EPH Receptor A2 antibody (ABIN179724) Images back to top
Application Notes Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.
Comment

Synonyms: Eph receptor tyrosine kinase A2

Restrictions For Research Use only

Handling

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Application Details References for anti-EPH Receptor A2 antibody (ABIN179724) Images back to top
Concentration 2 mg/mL
Buffer PBS, pH 7.2
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C
Storage Comment short term: 2 °C - 8 °C, long term: -20 °C

References for anti-EPH Receptor A2 antibody (ABIN179724)

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Application Details Handling Images back to top
Background publications

Ireton, Chen: "EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics." in: Current cancer drug targets, Vol. 5, Issue 3, pp. 149-57, 2005

Brantley-Sieders, Schmidt, Parker, Chen: "Eph receptor tyrosine kinases in tumor and tumor microenvironment." in: Current pharmaceutical design, Vol. 10, Issue 27, pp. 3431-42, 2004

Nakamoto, Bergemann: "Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis." in: Microscopy research and technique, Vol. 59, Issue 1, pp. 58-67, 2002

Lindberg, Hunter: "cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases." in: Molecular and cellular biology, Vol. 10, Issue 12, pp. 6316-24, 1991

Images

Product Details anti-EPH Receptor A2 Antibody Target Details EPH Receptor A2 Application Details Handling References for anti-EPH Receptor A2 antibody (ABIN179724) back to top
Supplier Images
 image for anti-EPH Receptor A2 (EPHA2) antibody (ABIN179724) FACS analysis of BOSC23 cells using Kalpha-5H5. BOSC23 cells were transiently trans-f...
 image for anti-EPH Receptor A2 (EPHA2) antibody (ABIN179724) Spectral Confocal Microscopy of CHO cells using K?-5H5. CHO cells were transiently tr...
 image for anti-EPH Receptor A2 (EPHA2) antibody (ABIN179724) SDS-PAGE analysis of purified K?-5H5 monoclonal antibody. Lane 1: molecular weight ma...
SDS-PAGE (SDS) image for anti-EPH Receptor A2 (EPHA2) antibody (ABIN179724) SDS-PAGE analysis of purified Kα-5H5 monoclonal antibody. Lane 1: molecular weight ma...
Flow Cytometry (FACS) image for anti-EPH Receptor A2 (EPHA2) antibody (ABIN179724) FACS analysis of BOSC23 cells using Kα-5H5. BOSC23 cells were transiently trans-fecte...
Immunofluorescence (IF) image for anti-EPH Receptor A2 (EPHA2) antibody (ABIN179724) Spectral Confocal Microscopy of CHO cells using Kα-5H5. CHO cells were transiently tr...