Browse our EPH Receptor A3 Proteins (EPHA3)

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EPH Receptor A3 Proteins (EPHA3)
On are 24 EPH Receptor A3 (EPHA3) Proteins from 7 different suppliers available. Additionally we are shipping EPH Receptor A3 Antibodies (134) and EPH Receptor A3 Kits (18) and many more products for this protein. A total of 191 EPH Receptor A3 products are currently listed.
AW492086, CEK4, EK4, End3, epha3, epha4, etID309879.24, ETK, ETK1, HEK, HEK4, Mek4, rtk2, rtk7, TYRO4, zgc:100780
list all proteins Gene Name GeneID UniProt
EPHA3 13837  
EPHA3 2042 P29320
EPHA3 29210 O08680

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EPH Receptor A3 Proteins (EPHA3) by Origin

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Top referenced EPH Receptor A3 Proteins

  1. Mouse (Murine) EPH Receptor A3 Protein expressed in Human Cells - ABIN2008644 : Wilkinson: Eph receptors and ephrins: regulators of guidance and assembly. in International review of cytology 2000 (PubMed)

More Proteins for EPH Receptor A3 Interaction Partners

Zebrafish EPH Receptor A3 (EPHA3) interaction partners

  1. EPHA6, a gene implicated in retinal axon guidance, is one of HMX1 targets in eye development.

Mouse (Murine) EPH Receptor A3 (EPHA3) interaction partners

  1. study delineates a mechanism in which NCAM (show NCAM1 Proteins) promotes ephrin-A5 (show EFNA5 Proteins)-dependent clustering of EphA3 through interaction of the NCAM (show NCAM1 Proteins) Ig2 domain and the EphA3 CRD (show CRX Proteins), stimulating EphA3 autophosphorylation and RhoA (show RHOA Proteins) signaling necessary for growth cone repulsion in GABAergic interneurons in vitro, which may extend to remodeling of axonal terminals of interneurons in vivo.

  2. Ephrin-A3 (show EFNA3 Proteins) has a role in promoting and maintaining slow muscle fiber identity during postnatal development and reinnervation

  3. the physiological role of the putative lung cancer tumor suppressor EPH receptor A3, is reported.

  4. ephrinA5/EphA3 triggers proteolysis of the neural cell adhesion molecule (NCAM (show NCAM1 Proteins)) by the metalloprotease (show ADAMTS7 Proteins) a disintegrin and metalloprotease (ADAM)10 (show ADAM10 Proteins) to promote growth cone collapse in neurons from mouse neocortex.

  5. EphA3 receptor localized only in neuronal cells of the hippocampus was enhanced without transcriptional regulation during synaptic plasticity through activation of the nicotinic acetylcholine receptor.

  6. Data show that a number of Eph (show EPHA1 Proteins) receptors and ephrins were expressed in hematopoietic stem cells.

  7. Neocortical expression of Epha3 during development remains stable in the absence of cellular contacts and thalamocortical connections.

  8. Retrograde labeling studies in EphA3(-/-) embryos and adults indicate that EphA3 is not necessary to direct motor axons to axial muscle targets.

  9. A discrepancy between mRNA and protein expression was found between early and later developmental stages, suggesting that EphA3 might regulate the formation of various neuronal networks in the developing brain.

  10. results indicate that EphA3 plays a crucial role in the development and morphogenesis of the cells that give rise to the atrioventricular valves and septa (show SEPT2 Proteins).

Human EPH Receptor A3 (EPHA3) interaction partners

  1. EphA3 promotes malignant transformation of colorectal epithelial cells by upregulating oncogenic signaling pathways.

  2. Data indicate that EPHA3 is involved in regulating the multidrug resistance (MDR) of small cell lung cancer (SCLC) via PI3K (show PIK3CA Proteins)/BMX (show BMX Proteins)/STAT3 (show STAT3 Proteins) signaling and may be a therapeutic target in SCLC.

  3. PTP-PEST (show PTPN12 Proteins) regulates EphA3 activation both by affecting cytoskeletal remodelling and through its direct action as a PTP (show SLC25A3 Proteins) controlling EphA3 phosphorylation.

  4. This study showed that EPHA3 gene involved in neuronal growth and cerebellum development and associated with neurological and psychological disorders.

  5. A novel association between the EPHA3 deletion and prostate cancer risk was observed in Finnish individuals.

  6. the structure of the ligand-binding domain of the EphA3 receptor in complex with its preferred ligand, ephrin-A5 (show EFNA5 Proteins), is reported.

  7. EphA3 forms dimers in the absence of ligand binding.

  8. Data indicate that hypoxia increased EphA3 receptor (EphA3) mRNA expression in EphA3+ endometrial multipotent mesenchymal stromal cells (eMSCs).

  9. EphA3 was induced by PC-1 (show PCSK1 Proteins) and contributed to the malignant progression of prostate cancer

  10. Based on the knowledge that EPHA4 (show EPHA4 Proteins) has been previously shown to rescue SOD1 (show SOD1 Proteins) transgenic mice from ALS (show IGFALS Proteins) phenotype and prolongs survival, EPHA3 may be a promising candidate for therepuetic interventions

EPH Receptor A3 (EPHA3) Protein Profile

Protein Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Alternative names and synonyms associated with EPH Receptor A3 (EPHA3)

  • eph receptor A4b (epha4b)
  • EPH receptor A3 (EPHA3)
  • EPH receptor A3 (LOC100222368)
  • Eph receptor A3 (Epha3)
  • EPH receptor A3 (Epha3)
  • eph-like kinase 1 (ek1)
  • AW492086 protein
  • CEK4 protein
  • EK4 protein
  • End3 protein
  • epha3 protein
  • epha4 protein
  • etID309879.24 protein
  • ETK protein
  • ETK1 protein
  • HEK protein
  • HEK4 protein
  • Mek4 protein
  • rtk2 protein
  • rtk7 protein
  • TYRO4 protein
  • zgc:100780 protein

Protein level used designations for EPH Receptor A3 Proteins (EPHA3)

eph-like receptor tyrosine kinase 2 , ephrin receptor EphA3 , EPH receptor A3 , ephrin type-A receptor 3-like , EK4 , EPH-like kinase 4 , ephrin type-A receptor 3 , tyrosine-protein kinase TYRO4 , tyrosine-protein kinase receptor ETK1 , TYRO4 protein tyrosine kinase , eph-like tyrosine kinase 1 , human embryo kinase 1 , rEK4 , tyrosine-protein kinase receptor REK4 , receptor tyrosine kinase , eph-like receptor tyrosine kinase 7 , tyrosine-protein kinase receptor ZEK1

64270 Danio rerio
460531 Pan troglodytes
694583 Macaca mulatta
100054527 Equus caballus
100084577 Ornithorhynchus anatinus
100405092 Callithrix jacchus
100439679 Pongo abelii
100470218 Ailuropoda melanoleuca
100587328 Nomascus leucogenys
100222368 Taeniopygia guttata
13837 Mus musculus
2042 Homo sapiens
29210 Rattus norvegicus
487930 Canis lupus familiaris
537951 Bos taurus
396402 Gallus gallus
100337658 Sus scrofa
100713095 Cavia porcellus
30311 Danio rerio
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