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Browse our EPH Receptor B4 Proteins (EPHB4)

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EPH Receptor B4 Proteins (EPHB4)
On are 26 EPH Receptor B4 (EPHB4) Proteins from 8 different suppliers available. Additionally we are shipping EPH Receptor B4 Antibodies (146) and EPH Receptor B4 Kits (6) and many more products for this protein. A total of 191 EPH Receptor B4 products are currently listed.
AI042935, ephB4a, ephb4b, HTK, MDK2, MGC130997, MYK1, TYRO11
list all proteins Gene Name GeneID UniProt
EPHB4 13846 P54761
EPHB4 2050 P54760
Rat EPHB4 EPHB4 686310  

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EPH Receptor B4 Proteins (EPHB4) by Origin

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Top referenced EPH Receptor B4 Proteins

  1. Human EPH Receptor B4 Protein expressed in Human Cells - ABIN2002400 : Bennett, Wang, Kuang, Wang, Groopman, Goeddel, Scadden: Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily. in The Journal of biological chemistry 1994 (PubMed)
    Show all 5 references for ABIN2002400

  2. Human EPH Receptor B4 Protein expressed in Baculovirus infected Insect Cells - ABIN2002404 : Noren, Lu, Freeman, Koolpe, Pasquale: Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 5 references for ABIN2002404

  3. Mouse (Murine) EPH Receptor B4 Protein expressed in Human Cells - ABIN2008001 : Murai, Pasquale: 'Eph'ective signaling: forward, reverse and crosstalk. in Journal of cell science 2003 (PubMed)
    Show all 5 references for ABIN2008001

  4. Human EPH Receptor B4 Protein expressed in HEK-293 Cells - ABIN2181023 : Kertesz, Krasnoperov, Reddy, Leshanski, Kumar, Zozulya, Gill: The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth. in Blood 2006 (PubMed)
    Show all 4 references for ABIN2181023

More Proteins for EPH Receptor B4 Interaction Partners

Mouse (Murine) EPH Receptor B4 (EPHB4) interaction partners

  1. These data indicate that ephrinB2 (show EFNB2 Proteins)/EphB4 signaling within the osteoblast lineage is required for late stages of osteoblast differentiation.

  2. EphB4 promotes endochondral ossification while inhibiting osteoclast development during callus formation.

  3. Selective inhibition of EphB4 using a functional blocking antibody results in defective lymphatic valve development.

  4. Overexpression of bone-specific Ephb4 clearly demonstrated prevention of the development and/or progression of fibrosis in OA synovial membrane

  5. EphB4-forward signaling plays a crucial role in the development of cardiac progenitor cells.

  6. EPHB4 plays an essential role in regulating small artery contractility and blood pressure

  7. the luminal epithelial EphB4 signaling contributes, most likely via wnt (show WNT2 Proteins) signaling, to the regulation of migration and cell fate of early progenitors and is involved in the determination of branching points along the mammary ductal tree

  8. thymocytes develop normally in the absence of EPHB4, and T cells derived from EPHB4-deleted thymic epithelian cells have normal function.

  9. These results are the first to identify EphB4 and its cross-talk with PDGFRbeta as unexpected vital determinants of tumor cell survival in alveolar rhabdomyosarcoma.

  10. Identify EphB4 signaling as a pathway allowing podocytes to survive transient capillary collapse during glomerular disease.

Human EPH Receptor B4 (EPHB4) interaction partners

  1. EphB4 facilitates stromal-mediated support of hematopoiesis in hematopoietic stem cells.

  2. N-(2,4)-dinitrophenyl-L-arginine (show GATM Proteins) Interacts with EphB4 and Functions as an EphB4 Kinase Modulator.

  3. Stimulation of Eph (show EPHA1 Proteins)-B4 function may be a candidate strategy for translation to human clinical trials designed to inhibit venous neointimal hyperplasia.

  4. These genes may be potential biomarkers for identification of subclinical lymph node involvement in papillary thyroid carcinoma (PTC (show F9 Proteins))

  5. EPHB4 oncogenomic network provides a molecular basis for its role in tumor progression and points to EPHB4 as a potential tumor aggressiveness biomarker and drug target in gastroesophageal cancers

  6. CTLA4 (show CTLA4 Proteins) modification maintains EphB4 expression in mesenchymal stem cells under immune activation conditions.

  7. Novel EPHB4 receptor tyrosine kinase (show RET Proteins) mutations have been found in lung cancer patients.

  8. Suggest role for EphB4/IGF1R (show IGF1R Proteins) signaling in regulation proliferation/migration of breast cancer cells.

  9. Results indicate EphB4 receptor as a critical mediator of erythropoietin (show EPO Proteins)-induced tumor progression.

  10. EphB4 regulates integrin Beta8 expression and integrin Beta8 plays a role in prostate cancer cells.

EPH Receptor B4 (EPHB4) Protein Profile

Protein Summary

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Alternative names and synonyms associated with EPH Receptor B4 (EPHB4)

  • EPH receptor B4 (EPHB4)
  • EPH receptor B4 (ephb4-a)
  • EPH receptor B4 (ephb4)
  • EPH receptor B4 (LOC100359286)
  • Eph receptor B4 (Ephb4)
  • EPH receptor B4 (Ephb4)
  • AI042935 protein
  • ephB4a protein
  • ephb4b protein
  • HTK protein
  • MDK2 protein
  • MGC130997 protein
  • MYK1 protein
  • TYRO11 protein

Protein level used designations for EPH Receptor B4 Proteins (EPHB4)

EPH receptor B4 , eph receptor tyrosine kinase , ephrin receptor EphB4 , ephrin type-B receptor 4-like , developmental kinase 2 , ephrin type-B receptor 4 , hepatoma transmembrane kinase , mDK-2 , tyrosine kinase MYK-1 , soluble EPHB4 variant 1 , soluble EPHB4 variant 2 , soluble EPHB4 variant 3 , tyrosine-protein kinase TYRO11 , tyrosine-protein kinase receptor HTK

100069098 Equus caballus
398362 Xenopus laevis
463610 Pan troglodytes
100191023 Xenopus laevis
100359286 Oryctolagus cuniculus
100461743 Pongo abelii
100483535 Ailuropoda melanoleuca
100497297 Xenopus (Silurana) tropicalis
100563254 Anolis carolinensis
100591047 Nomascus leucogenys
13846 Mus musculus
2050 Homo sapiens
489830 Canis lupus familiaris
100517028 Sus scrofa
515756 Bos taurus
686310 Rattus norvegicus
100735745 Cavia porcellus
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