Browse our EPH Receptor B4 Proteins (EPHB4)

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EPH Receptor B4 Proteins (EPHB4)
On are 28 EPH Receptor B4 (EPHB4) Proteins from 9 different suppliers available. Additionally we are shipping EPH Receptor B4 Antibodies (177) and EPH Receptor B4 Kits (10) and many more products for this protein. A total of 228 EPH Receptor B4 products are currently listed.
AI042935, ephB4a, ephb4b, HTK, MDK2, MGC130997, MYK1, TYRO11
list all proteins Gene Name GeneID UniProt
EPHB4 13846 P54761
EPHB4 2050 P54760
Rat EPHB4 EPHB4 686310  

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EPH Receptor B4 Proteins (EPHB4) by Origin

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Top referenced EPH Receptor B4 Proteins

  1. Human EPH Receptor B4 Protein expressed in Human Cells - ABIN2002400 : Bennett, Wang, Kuang, Wang, Groopman, Goeddel, Scadden: Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily. in The Journal of biological chemistry 1994 (PubMed)
    Show all 5 references for 2002400

  2. Human EPH Receptor B4 Protein expressed in Baculovirus infected Insect Cells - ABIN2002404 : Noren, Lu, Freeman, Koolpe, Pasquale: Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 5 references for 2002404

  3. Mouse (Murine) EPH Receptor B4 Protein expressed in Human Cells - ABIN2008001 : Murai, Pasquale: 'Eph'ective signaling: forward, reverse and crosstalk. in Journal of cell science 2003 (PubMed)
    Show all 5 references for 2008001

  4. Human EPH Receptor B4 Protein expressed in HEK-293 Cells - ABIN2181023 : Kertesz, Krasnoperov, Reddy, Leshanski, Kumar, Zozulya, Gill: The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth. in Blood 2006 (PubMed)
    Show all 4 references for 2181023

More Proteins for EPH Receptor B4 Interaction Partners

Mouse (Murine) EPH Receptor B4 (EPHB4) interaction partners

  1. These results identify EPHB4/ephrin B2 (show EFNB2 Proteins) signaling as critical to Hematopoietic stem and progenitor cells mobilization from bone marrow

  2. EphB4 plays an irreplaceable role in bone regeneration in an inflammatory microenvironment, whereas the functional loss of ephrinB2 (show EFNB2 Proteins) can be effectively compensated, most possibly by other ephrins with similar chemical structures

  3. Eph (show EPHA1 Proteins)-B4 stimulates eNOS (show NOS3 Proteins) phosphorylation in vitro and may mediate vein graft adaptation by regulation of eNOS (show NOS3 Proteins) activity in vivo.

  4. These data indicate that ephrinB2 (show EFNB2 Proteins)/EphB4 signaling within the osteoblast lineage is required for late stages of osteoblast differentiation.

  5. EphB4 promotes endochondral ossification while inhibiting osteoclast development during callus formation.

  6. Selective inhibition of EphB4 using a functional blocking antibody results in defective lymphatic valve development.

  7. Overexpression of bone-specific Ephb4 clearly demonstrated prevention of the development and/or progression of fibrosis in OA synovial membrane

  8. EphB4-forward signaling plays a crucial role in the development of cardiac progenitor cells.

  9. EPHB4 plays an essential role in regulating small artery contractility and blood pressure

  10. the luminal epithelial EphB4 signaling contributes, most likely via wnt (show WNT2 Proteins) signaling, to the regulation of migration and cell fate of early progenitors and is involved in the determination of branching points along the mammary ductal tree

Human EPH Receptor B4 (EPHB4) interaction partners

  1. The expression of EPHB4 was increased in gastric cancer and increased EPHB4 expression was correlated with poor survival. Knockdown of EPHB4 promoted adhesion and exerted diverse effects on migration of gastric cancer cells.

  2. EphB4 protein acts as a tumour promoter associated with proliferation, invasion, and angiogenesis, and may be used as a potential colorectal cancer (CRC (show CALR Proteins)) therapeutic target.

  3. Study illustrates that aberrant activation of EphB4/ephrinB2 (show EFNB2 Proteins) may mediate chronic myeloid leukemia (show BCL11A Proteins) resistance involved in cytoskeletal proteins.

  4. both EphA2 (show EPHA2 Proteins) and EphB4 show potential as target for image-guided colorectal cancer surgery, but EphB4 seems to have the best characteristics with respect to tumor/normal mucosa distribution.

  5. Survival analysis showed that the non-small cell lung carcinoma patients with enhanced expression of CK7 (show KRT7 Proteins), ELF3 (show ELF3 Proteins), EGFR (show EGFR Proteins), and EphB4 mRNA in peripheral blood leukocytes had poorer disease-free survival and overall survival than those without.

  6. Enhanced EphB4 expression was significantly associated with Thyroid Lesions.

  7. LISA method may be considered rapid and sensitive enough to detect even low levels of total and phosphorylated EphB4 Cost-effectiveness of this method for the detection of differential expression of EphB4 proteins in clinics is also noticeable.

  8. EphB4 facilitates stromal-mediated support of hematopoiesis in hematopoietic stem cells.

  9. N-(2,4)-dinitrophenyl-L-arginine (show GATM Proteins) Interacts with EphB4 and Functions as an EphB4 Kinase Modulator.

  10. Stimulation of Eph (show EPHA1 Proteins)-B4 function may be a candidate strategy for translation to human clinical trials designed to inhibit venous neointimal hyperplasia.

EPH Receptor B4 (EPHB4) Protein Profile

Protein Summary

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Alternative names and synonyms associated with EPH Receptor B4 (EPHB4)

  • EPH receptor B4 (EPHB4)
  • EPH receptor B4 (ephb4-a)
  • EPH receptor B4 (ephb4)
  • EPH receptor B4 (LOC100359286)
  • Eph receptor B4 (Ephb4)
  • EPH receptor B4 (Ephb4)
  • AI042935 protein
  • ephB4a protein
  • ephb4b protein
  • HTK protein
  • MDK2 protein
  • MGC130997 protein
  • MYK1 protein
  • TYRO11 protein

Protein level used designations for EPH Receptor B4 Proteins (EPHB4)

EPH receptor B4 , eph receptor tyrosine kinase , ephrin receptor EphB4 , ephrin type-B receptor 4-like , developmental kinase 2 , ephrin type-B receptor 4 , hepatoma transmembrane kinase , mDK-2 , tyrosine kinase MYK-1 , soluble EPHB4 variant 1 , soluble EPHB4 variant 2 , soluble EPHB4 variant 3 , tyrosine-protein kinase TYRO11 , tyrosine-protein kinase receptor HTK

100069098 Equus caballus
398362 Xenopus laevis
463610 Pan troglodytes
100191023 Xenopus laevis
100359286 Oryctolagus cuniculus
100461743 Pongo abelii
100483535 Ailuropoda melanoleuca
100497297 Xenopus (Silurana) tropicalis
100563254 Anolis carolinensis
100591047 Nomascus leucogenys
13846 Mus musculus
2050 Homo sapiens
489830 Canis lupus familiaris
100517028 Sus scrofa
515756 Bos taurus
686310 Rattus norvegicus
100735745 Cavia porcellus
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