anti-Rat (Rattus) Ephrin A1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Ephrin A1 Antibody (supplied by: Log in to see )

Antigen
Ephrin A1 (EFNA1) Antibodies
  • Xefrin-A1
  • b61
  • ecklg
  • efl1
  • efna1
  • efna1a
  • elfa-a
  • epha1
  • eplg1
  • lerk1
  • tnfaip4
  • xelf-a'
  • xelfa
  • AI325262
  • B61
  • Efl1
  • Epl1
  • Eplg1
  • Lerk1
  • ECKLG
  • EFL1
  • EPLG1
  • LERK-1
  • LERK1
  • TNFAIP4
  • efna1b
  • MGC130661
  • ephrin-A1
  • ephrin A1b
  • ephrin A1
  • ephrin A1-like
  • efna1-a
  • efna1
  • EFNA1
  • efna1b
  • Efna1
  • LOC100344921
  • efna1-b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
66
58
47
3
3
3
Host
Rabbit
64
15
15
2
Clonality
Polyclonal
Conjugate
This Ephrin A1 antibody is un-conjugated
5
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
67
41
18
12
11
9
3
2
2
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN734108
$ 295.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2812858 IF (p) Alexa Fluor 594 Rabbit IgG AA 140-182 Log in to see Polyclonal
1 ABIN734112 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN734111 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN734113 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN734115 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN734114 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN895445 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN895446 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN895442 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN895444 IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal
1 ABIN5002036 IF (p) Alexa Fluor 680 Rabbit IgG AA 140-182 Log in to see Polyclonal
1 ABIN5002037 IF (p) Alexa Fluor 750 Rabbit IgG AA 140-182 Log in to see Polyclonal

General

Antigen Ephrin A1 (EFNA1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(66), (58), (47), (3), (3), (3)
Host Rabbit
(64), (15), (15), (2)
Clonality
Polyclonal
Conjugate This Ephrin A1 antibody is un-conjugated
(5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(67), (41), (18), (12), (11), (9), (3), (2), (2), (1), (1), (1)
Supplier Log in to see

Product Details anti-Ephrin A1 Antibody

Target Details Ephrin A1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Ephrin A1
Isotype IgG

Target Details Ephrin A1

Product Details anti-Ephrin A1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Ephrin A1 (EFNA1 Antibody Abstract)
Background

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.

Subcellular location: Secreted, Cell membrane

Synonyms: Ephrin-A1, EFNA1, EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor alpha-induced protein 4, EPLG1, LERK1, TNFAIP4

Gene ID 1942
UniProt P20827
Research Area Neurology, Tyrosine Kinases, Angiogenesis
Pathways RTK Signaling

Application Details

Product Details anti-Ephrin A1 Antibody Target Details Ephrin A1 Handling Images back to top
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-Ephrin A1 Antibody Target Details Ephrin A1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-Ephrin A1 Antibody Target Details Ephrin A1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Ephrin A1 (EFNA1) antibody (ABIN734108) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti Ep...