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Browse our Ephrin A1 Proteins (EFNA1)

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Ephrin A1 Proteins (EFNA1)
On www.antibodies-online.com are 32 Ephrin A1 (EFNA1) Proteins from 10 different suppliers available. Additionally we are shipping Ephrin A1 Antibodies (79) and Ephrin A1 Kits (37) and many more products for this protein. A total of 161 Ephrin A1 products are currently listed.
Synonyms:
AI325262, B61, ECKLG, EFL1, efna1, efna1a, efna1b, elfa-a, epha1, Epl1, EPLG1, LERK-1, LERK1, MGC130661, TNFAIP4, Xefrin-A1, xelf-a', xelfa
list all proteins Gene Name GeneID UniProt
EFNA1 13636 P52793
EFNA1 94268 P97553
EFNA1 1942 P20827

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Ephrin A1 Proteins (EFNA1) by Origin

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Top referenced Ephrin A1 Proteins

  1. Human Ephrin A1 Protein expressed in HEK-293 Cells - ABIN2180992 : Wykosky, Palma, Gibo, Ringler, Turner, Debinski: Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor. in Oncogene 2008 (PubMed)
    Show all 3 references for ABIN2180992

  2. Human Ephrin A1 Protein expressed in Escherichia coli (E. coli) - ABIN667976 : Bartley, Hunt, Welcher, Boyle, Parker, Lindberg, Lu, Colombero, Elliott, Guthrie: B61 is a ligand for the ECK receptor protein-tyrosine kinase. in Nature 1994 (PubMed)
    Show all 2 references for ABIN667976

  3. Human Ephrin A1 Protein expressed in Human Cells - ABIN2003539 : Flanagan, Vanderhaeghen: The ephrins and Eph receptors in neural development. in Annual review of neuroscience 1998 (PubMed)

More Proteins for Ephrin A1 Interaction Partners

Mouse (Murine) Ephrin A1 (EFNA1) interaction partners

  1. ADAM12 (show ADAM12 Proteins) enhanced ephrin-A1 cleavage in response to transforming growth factor-betra1 in primary tumors.

  2. S100A8 (show S100A8 Proteins) and ephrin-A1 contribute to lung metastasis.

  3. We used in utero electroporation-mediated EphA7 overexpression in developing somatosensory corticothalamic axons to dissect EphA7/ephrin-A-dependent mechanisms involved in regulating both initial targeting and postnatal growth of the CT projections.

  4. Elevated levels of ephrin-A1 may contribute to diabetic keratopathies by persistently engaging EphA2 (show EPHA2 Proteins) and prohibiting Akt (show AKT1 Proteins)-dependent corneal epithelial repair processes.

  5. Data indicate that ephrin-A1 regulates cardiac valve development, making ephrin-A1-deficient mice a novel model for congenital heart defects.

  6. Cooperation between Slit2 and ephrin-A1 regulates a balance between the pro- and antiangiogenic functions of Slit2.

  7. ephrin-A1 has a positive role in tumor growth in vivo, and are consistent with previous reports of ephrin-A1 acting through EphA receptors in the tumor microenvironment in vivo.

  8. Immunohistological analyses reveal strong ephrin-A1 expression in lung tissue, low expression in cortical areas of lymph nodes, and none in T cell/B cell areas of the spleen.

  9. Whole-mount in situ hybridization revealed overlapping expression of the Epha1 (show EPHA1 Proteins) receptor and its high-affinity ligands ephrin A1 (Efna1) and ephrin A3 (Efna3 (show EFNA3 Proteins)) in the primitive streak and the posterior paraxial mesoderm during early mouse development.

  10. Ephrins A1 and A5 are substrates for a cross-linking enzyme, tissue transglutaminase, which mediates the formation of oligomeric ephrin.

Human Ephrin A1 (EFNA1) interaction partners

  1. Findings show that EFNA1 expression is a useful marker for predicting a high risk of recurrence in hepatocellular carcinoma patients but not EPHA2 (show EPHA2 Proteins).

  2. Results suggest that EFNA1 is involved in colorectal tumorigenesis, and rs12904 A>G polymorphism in the 3' UTR of EFNA1 is associated with CRC (show CALR Proteins) susceptibility in a Chinese population.

  3. EphA2 (show EPHA2 Proteins)-ephrinA1 trans-endocytosis is sensitive to the mechanical properties of a cell's microenvironment

  4. Ephrin-A1 is upregulated in tumor microenvironment and promotes angiogenesis through a coordinated cross-talk with PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)-dependent eNOS (show NOS3 Proteins) activation.

  5. The interaction between ephrin-As, Eph (show EPHA1 Proteins) receptors and integrin alpha3 is plausibly important for the crosstalk between Eph (show EPHA1 Proteins) and integrin signalling pathways at the membrane protrusions and in the migration of brain cancer cells.

  6. Increased expression of EFNA1 mRNA is associated with gastric cancer.

  7. Expression of EPHRIN-A1 tends to be associated with worse survival in head and neck cancer.

  8. EFNA1 expression is a useful marker for predicting high risk of relapse and cancer-related death in patients who have undergone curative resection for CRC (show CALR Proteins).

  9. Findings suggest that the glycosylation on ephrin-A1 plays a critical role in the binding and activation of the EphA2 (show EPHA2 Proteins) receptor.

  10. present study showed a high expression of EphA2 (show EPHA2 Proteins)/ephrinA1 in adenoid cystic carcinoma. EphA2 (show EPHA2 Proteins)/ephrinA1 can serve as a novel therapy target for adenoid cystic carcinoma.

Pig (Porcine) Ephrin A1 (EFNA1) interaction partners

  1. The Eph-Ephrin A system might play an important role in regulating the swine contact between blastocysts and endometrium during embryo implantation.

Ephrin A1 (EFNA1) Protein Profile

Protein Summary

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.

Alternative names and synonyms associated with Ephrin A1 (EFNA1)

  • ephrin-A1 (efna1-a)
  • ephrin-A1 (efna1)
  • ephrin-A1 (EFNA1)
  • ephrin A1b (efna1b)
  • ephrin A1 (Efna1)
  • ephrin A1-like (LOC100344921)
  • ephrin-A1 (Efna1)
  • ephrin-A1 (efna1-b)
  • AI325262 protein
  • B61 protein
  • ECKLG protein
  • EFL1 protein
  • efna1 protein
  • efna1a protein
  • efna1b protein
  • elfa-a protein
  • epha1 protein
  • Epl1 protein
  • EPLG1 protein
  • LERK-1 protein
  • LERK1 protein
  • MGC130661 protein
  • TNFAIP4 protein
  • Xefrin-A1 protein
  • xelf-a' protein
  • xelfa protein

Protein level used designations for Ephrin A1 Proteins (EFNA1)

EPH-related receptor tyrosine kinase ligand 1 , LERK-1 , XELF-a , eph ligand family-a , ephrin-A1a , ephrin-A1 , ephrin A1 , immediate early response protein B61 , TNF alpha-induced protein 4 , eph-related receptor tyrosine kinase ligand 1 , ligand of eph-related kinase 1 , tumor necrosis factor alpha-induced protein 4 , tumor necrosis factor, alpha-induced protein 4 , ephrin-A1 b

GENE ID SPECIES
397809 Xenopus laevis
496637 Xenopus (Silurana) tropicalis
740136 Pan troglodytes
494151 Danio rerio
13636 Mus musculus
94268 Rattus norvegicus
100344921 Oryctolagus cuniculus
1942 Homo sapiens
100732408 Cavia porcellus
490431 Canis lupus familiaris
100144501 Sus scrofa
507319 Bos taurus
101105624 Ovis aries
496064 Xenopus laevis
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