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Browse our anti-ERBB3 (ERBB3) Antibodies

Full name:
anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Antibodies (ERBB3)
On www.antibodies-online.com are 531 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antibodies from 33 different suppliers available. Additionally we are shipping ERBB3 Proteins (43) and ERBB3 Kits (32) and many more products for this protein. A total of 635 ERBB3 products are currently listed.
Synonyms:
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3
list all antibodies Gene Name GeneID UniProt
ERBB3 2065 P21860
ERBB3 29496 Q62799
ERBB3 13867 Q61526

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Top referenced anti-ERBB3 Antibodies

  1. Human Polyclonal ERBB3 Primary Antibody for FACS, IHC (p) - ABIN391949 : Katoh, Yazaki, Sugimura, Terada: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 7 references for ABIN391949

  2. Human Polyclonal ERBB3 Primary Antibody for IF, IHC (p) - ABIN319383 : Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 4 references for ABIN319383

  3. Human Monoclonal ERBB3 Primary Antibody for IHC (p) - ABIN1687349 : Wang, Huang, Lyu, Cai, Yang, Li, Tan, Edgerton, Thor, Lee, Liu: Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. in Breast cancer research : BCR 2014 (PubMed)
    Show all 2 references for ABIN1687349

  4. Human Monoclonal ERBB3 Primary Antibody for IHC (p) - ABIN1687359 : Huang, Wang, Lyu, Cai, Yang, Wang, Liu: The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. in Molecular cancer 2014 (PubMed)
    Show all 2 references for ABIN1687359

  5. Human Monoclonal ERBB3 Primary Antibody for IHC, ELISA - ABIN969112 : Sakai, Yokote, Murakami-Murofushi, Tamura, Saijo, Nishio: Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway. in Cancer science 2007 (PubMed)
    Show all 2 references for ABIN969112

  6. Human Monoclonal ERBB3 Primary Antibody for ICC, ELISA - ABIN969114 : Sassen, Rochon, Wild, Hartmann, Hofstaedter, Schwarz, Brockhoff: Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients. in Breast cancer research : BCR 2008 (PubMed)
    Show all 2 references for ABIN969114

  7. Human Monoclonal ERBB3 Primary Antibody for EIA, FACS - ABIN119014 : Rajkumar, Gullick: A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. in British journal of cancer 1994 (PubMed)

  8. Cow (Bovine) Polyclonal ERBB3 Primary Antibody for WB - ABIN374599 : van der Horst, Weber, Ullrich: Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. in International journal of cancer. Journal international du cancer 2004 (PubMed)

More Antibodies against ERBB3 Interaction Partners

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. YAP (show YAP1 Antibodies) induces the expression of epidermal growth factor (EGF (show EGF Antibodies)) receptors (EGFR (show EGFR Antibodies), ERBB3) and production of EGF (show EGF Antibodies)-like ligands (HBEGF (show HBEGF Antibodies), NRG1 (show NRG1 Antibodies) and NRG2 (show NRG2 Antibodies)); YAP (show YAP1 Antibodies) induces the expression of epidermal growth factor (EGF (show EGF Antibodies)) receptors (EGFR (show EGFR Antibodies), ERBB3) and production of EGF (show EGF Antibodies)-like ligands (HBEGF (show HBEGF Antibodies), NRG1 (show NRG1 Antibodies) and NRG2 (show NRG2 Antibodies))

  2. the phosphorylation levels of ErbB2 (show ERBB2 Antibodies), ErbB3 and Akt (show AKT1 Antibodies) and the protein levels of cyclin D1 (show CCND1 Antibodies) were decreased by lapatinib treatment of HSC3, HSC4 and Ca9 (show CA9 Antibodies)-22 cells

  3. In high-grade serous ovarian carcinoma (HGSC), high HER3 mRNA expression was a favorable prognostic factor for survival, while for high HER3 protein expression, a trend towards better survival was seen. A subgroup of HGSC with negative HER3 staining and negative HER3 mRNA levels showed most unfavorable survival.

  4. ERBB3 and ERBB4 (show ERBB4 Antibodies) have roles in lung adenocarcinoma

  5. Results suggest that silibinin is a potential anti-cancer drug to inhibit proliferative and invasive characteristics of the epithelial ovarian cancer (EOC) cells that exhibit an autocrine heregulin (HRG (show NRG1 Antibodies))/HER3 protein (HRG (show NRG1 Antibodies)/HER3) pathway.

  6. findings suggest that HBx promotes the progression of hepatocellular carcinoma by decreasing the stability of Nrdp1 (show RNF41 Antibodies), which results in up-regulation of ErbB3

  7. High HER3 expression in colon cancer was associated to distal colon location and low-grade tumor.

  8. Correlate ERBB3 gene SNPs with rheumatoid arthritis susceptibility.

  9. Nrdp1S is a tumour suppressor that which potentiates the Nrdp1 (show RNF41 Antibodies)-mediated ubiquitination and degradation of ErbB3. An Nrdp1S deficiency may also be an important factor in the loss of Nrdp1 (show RNF41 Antibodies).

  10. In response to trastuzumab, both HER3 and the metalloprotease (show ADAM8 Antibodies) ADAM10 (show ADAM10 Antibodies) are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 ligand heregulin (show NRG1 Antibodies) from the cell surface to activate HER3 and confer resistance to trastuzumab by inducing compensatory growth factor receptor (show RYK Antibodies) signaling.

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. nuc-ErbB3 directly regulates levels of H3K27me3 in Schwann cells

  2. Data indicate that Sonic hedgehog (Shh (show SHH Antibodies)) stimulate branching morphogenesis (BrM (show SMARCA2 Antibodies)) and induced synthesis of mRNAs for Ptch1 (show PTCH1 Antibodies) protein, epidermal growth factor (EGF (show EGF Antibodies)) and receptors of the ErbB (show EGFR Antibodies) receptors ErbB1 (show EGFR Antibodies), ErbB2 (show ERBB2 Antibodies) and ErbB3.

  3. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  4. The expression of ERBB3 in combination with ERBB4 (show ERBB4 Antibodies) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  5. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (show AKT1 Antibodies) pathway and promoting erbB2 (show ERBB2 Antibodies)-driven mammary/breast tumorigenesis.

  6. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (show STAT3 Antibodies) activation.

  7. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  8. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  9. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

  10. Myocilin (show MYOC Antibodies) binds to ErbB2 (show ERBB2 Antibodies)/ErbB3, activates these receptors, and affects the downstream PI3K-AKT (show AKT1 Antibodies) signaling pathway

ERBB3 Antigen Profile

Antigen Summary

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) antibody
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) antibody
  • c-erbB-3 antibody
  • c-erbB3 antibody
  • C76256 antibody
  • Erbb-3 antibody
  • ERBB3 antibody
  • erbB3-S antibody
  • Erbb3r antibody
  • Her3 antibody
  • LCCS2 antibody
  • MDA-BF-1 antibody
  • nuc-ErbB3 antibody
  • p45-sErbB3 antibody
  • p85-sErbB3 antibody
  • p180-ErbB3 antibody

Protein level used designations for ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

GENE ID SPECIES
481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
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