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Browse our anti-ERBB3 (ERBB3) Antibodies

Full name:
anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Antibodies (ERBB3)
On www.antibodies-online.com are 425 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Antibodies from 31 different suppliers available. Additionally we are shipping ERBB3 Proteins (40) and ERBB3 Kits (27) and many more products for this protein. A total of 522 ERBB3 products are currently listed.
Synonyms:
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3
list all antibodies Gene Name GeneID UniProt
ERBB3 2065 P21860
ERBB3 29496 Q62799
ERBB3 13867 Q61526

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anti-Human ERBB3 Antibodies:

anti-Rat (Rattus) ERBB3 Antibodies:

anti-Mouse (Murine) ERBB3 Antibodies:

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Top referenced anti-ERBB3 Antibodies

  1. Human Polyclonal ERBB3 Primary Antibody for FACS, IHC (p) - ABIN391949 : Katoh, Yazaki, Sugimura, Terada: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 7 references for ABIN391949

  2. Human Polyclonal ERBB3 Primary Antibody for IF, IHC (p) - ABIN319383 : Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 4 references for ABIN319383

  3. Human Monoclonal ERBB3 Primary Antibody for IHC (p) - ABIN1687349 : Wang, Huang, Lyu, Cai, Yang, Li, Tan, Edgerton, Thor, Lee, Liu: Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. in Breast cancer research : BCR 2014 (PubMed)
    Show all 2 references for ABIN1687349

  4. Human Monoclonal ERBB3 Primary Antibody for IHC (p) - ABIN1687359 : Huang, Wang, Lyu, Cai, Yang, Wang, Liu: The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. in Molecular cancer 2014 (PubMed)
    Show all 2 references for ABIN1687359

  5. Human Monoclonal ERBB3 Primary Antibody for ELISA, WB - ABIN969113 : Sakai, Yokote, Murakami-Murofushi, Tamura, Saijo, Nishio: Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway. in Cancer science 2007 (PubMed)
    Show all 2 references for ABIN969113

  6. Human Monoclonal ERBB3 Primary Antibody for ICC, ELISA - ABIN969114 : Sassen, Rochon, Wild, Hartmann, Hofstaedter, Schwarz, Brockhoff: Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients. in Breast cancer research : BCR 2008 (PubMed)
    Show all 2 references for ABIN969114

  7. Human Monoclonal ERBB3 Primary Antibody for EIA, FACS - ABIN119014 : Rajkumar, Gullick: A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. in British journal of cancer 1994 (PubMed)

  8. Cow (Bovine) Polyclonal ERBB3 Primary Antibody for WB - ABIN782970 : van der Horst, Weber, Ullrich: Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. in International journal of cancer. Journal international du cancer 2004 (PubMed)

More Antibodies against ERBB3 Interaction Partners

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. NRF2 (show GABPA Antibodies) regulates both HER2 (show ERBB2 Antibodies) and HER3 receptors to influence cellular responses to HER2 (show ERBB2 Antibodies) targeting.

  2. our results suggest that HER3 over-expression may be associated with worse overall survival in gastric cancers

  3. Study shows that ERBB3 is a novel regulator of beta-cell apoptosis and found rs2292239 strongly correlated with residual b-cell function and metabolic control in children with type 1 diabetes.

  4. Authors show experimental evidence for an ErbB3 gain-of-function point mutation located in the C-lobe asymmetric dimerization interface, which shows enhanced phosphorylation at low ligand dose associated with increased kinase activity.

  5. critical pathophysiologic event in the evolution of HER2 (show ERBB2 Antibodies)-amplified cancers is the loss of the input signals that normally drive TORC2 (show CRTC2 Antibodies) signaling, repositioning it under Akt (show AKT1 Antibodies) dependency, and fundamentally altering the role of HER3

  6. HER2 (show ERBB2 Antibodies)/HER3 interaction and increased expression was linked to risk for poor outcome in lung cancer patients.

  7. Data show that cotreatment with anti-ERBB3 proto-oncogene (show RAB1A Antibodies) protein antibody seribantumab and letrozole had increased antitumor activity.

  8. findings newly identify a physiological function of the NRG1 (show NRG1 Antibodies)-ErbB2 (show ERBB2 Antibodies)-ErbB3 axis in trophoblast survival during human placental development.

  9. Expression and Prognostic Significance of Human Epidermal Growth Factor (show EGF Antibodies) Receptors 1, 2 and 3 in Periampullary Adenocarcinoma

  10. HPV 16 E2 can modulate ErbB-3 by interacting with Nrdp-1 (show RNF41 Antibodies), which is involved in the regulation of this receptor, via ubiquitination and degradation.

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Data indicate that Sonic hedgehog (Shh (show SHH Antibodies)) stimulate branching morphogenesis (BrM (show SMARCA2 Antibodies)) and induced synthesis of mRNAs for Ptch1 (show PTCH1 Antibodies) protein, epidermal growth factor (EGF (show EGF Antibodies)) and receptors of the ErbB (show EGFR Antibodies) receptors ErbB1 (show EGFR Antibodies), ErbB2 (show ERBB2 Antibodies) and ErbB3.

  2. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  3. The expression of ERBB3 in combination with ERBB4 (show ERBB4 Antibodies) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  4. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (show AKT1 Antibodies) pathway and promoting erbB2 (show ERBB2 Antibodies)-driven mammary/breast tumorigenesis.

  5. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (show STAT3 Antibodies) activation.

  6. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  7. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  8. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

  9. Myocilin (show MYOC Antibodies) binds to ErbB2 (show ERBB2 Antibodies)/ErbB3, activates these receptors, and affects the downstream PI3K-AKT (show AKT1 Antibodies) signaling pathway

  10. PIK3CA (show PIK3CA Antibodies)(H1047R)-driven tumor growth and PI3K signaling can occur independently of ErbB3 receptor tyrosine kinases.

ERBB3 Antigen Profile

Antigen Summary

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) antibody
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) antibody
  • c-erbB-3 antibody
  • c-erbB3 antibody
  • C76256 antibody
  • Erbb-3 antibody
  • ERBB3 antibody
  • erbB3-S antibody
  • Erbb3r antibody
  • Her3 antibody
  • LCCS2 antibody
  • MDA-BF-1 antibody
  • nuc-ErbB3 antibody
  • p45-sErbB3 antibody
  • p85-sErbB3 antibody
  • p180-ErbB3 antibody

Protein level used designations for ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

GENE ID SPECIES
481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
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