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Browse our anti-ERBB4 (ERBB4) Antibodies

Full name:
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) Antibodies (ERBB4)
On www.antibodies-online.com are 354 V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies from 27 different suppliers available. Additionally we are shipping ERBB4 Proteins (32) and ERBB4 Kits (7) and many more products for this protein. A total of 412 ERBB4 products are currently listed.
Synonyms:
c-erbB-4, erbb4, HER4, p180erbB4, si:ch211-227n20.1
list all antibodies Gene Name GeneID UniProt
ERBB4 13869 Q61527
ERBB4 59323 Q62956
ERBB4 2066 Q15303

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Top referenced anti-ERBB4 Antibodies

  1. Human Polyclonal ERBB4 Primary Antibody for EIA, IHC (p) - ABIN359846 : Williams, Trout, Gallo, Pitfield, Bryant, Penington, Riese: A constitutively active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines. in Cancer letters 2003 (PubMed)
    Show all 5 references for ABIN359846

  2. Human Polyclonal ERBB4 Primary Antibody for EIA, IHC (p) - ABIN358140 : Tanimura, Nakago, Murakoshi, Takekida, Moriyama, Matsuo, Hashimoto, Maruo: Changes in the expression and cytological localization of betacellulin and its receptors (ErbB-1 and ErbB-4) in the trophoblasts in human placenta over the course of pregnancy. in European journal of endocrinology / European Federation of Endocrine Societies 2004 (PubMed)
    Show all 5 references for ABIN358140

  3. Human Polyclonal ERBB4 Primary Antibody for IHC (p), WB - ABIN391950 : Cheng, Tikhomirov, Zhou, Carpenter: Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for ABIN391950

  4. Human Polyclonal ERBB4 Primary Antibody for IHC (p), WB - ABIN391951 : Komuro, Nagai, Navin, Sudol: WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN391951

  5. Human Polyclonal ERBB4 Primary Antibody for IF, IHC (p) - ABIN389572 : Prickett, Agrawal, Wei, Yates, Lin, Wunderlich, Cronin, Cruz, Rosenberg, Samuels: Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. in Nature genetics 2009 (PubMed)
    Show all 2 references for ABIN389572

  6. Human Monoclonal ERBB4 Primary Antibody for Func, FACS - ABIN180326 : Chen, Levkowitz, Tzahar, Karunagaran, Lavi, Ben-Baruch, Leitner, Ratzkin, Bacus, Yarden: An immunological approach reveals biological differences between the two NDF/heregulin receptors, ErbB-3 and ErbB-4. in The Journal of biological chemistry 1996 (PubMed)
    Show all 2 references for ABIN180326

  7. Human Polyclonal ERBB4 Primary Antibody for IF (p), IHC (p) - ABIN737436 : Zhao: Expression and Localization of Neuregulin-1 (Nrg1) and ErbB2/ErbB4 Receptors in Main Endocrine Organs of the Rhesus Monkey. in International journal of endocrinology and metabolism 2013 (PubMed)

  8. Human Polyclonal ERBB4 Primary Antibody for EIA, IHC (p) - ABIN358139 : Burns, Li, Cheney, Ou, Franlin-Pfeifer, Kuklin, Zhang: Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 (PubMed)

More Antibodies against ERBB4 Interaction Partners

Rhesus Monkey V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) interaction partners

  1. the NRG-ErbB4 signaling pathway can potentially influence many functional systems throughout the brain of primates, and suggest that major sites of action are areas of the "corticolimbic" network

  2. Widespread expression of ErbB4 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization, with higher levels in grey matter compared to white matter.

Xenopus laevis V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) interaction partners

  1. ErbB (show EGFR Antibodies) signaling control both convergent extension and head mesoderm migration during gastrulation.

Mouse (Murine) V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) interaction partners

  1. A combination of miRNAs induced via endothelial coculture improved embryonic-stem-cell-derived cardiomyocytes maturity, in part through suppression of ErbB4 signaling.

  2. The expression of ERBB3 (show ERBB3 Antibodies) in combination with ERBB4 significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  3. These results suggest a mechanism by which cross-talk between DISC1 (show DISC1 Antibodies) and NRG1 (show NRG1 Antibodies)-ErbB4 signalling may contribute to these deficits.

  4. Findings reveal an intimate reciprocal relationship between ErbB4 and GluN2b (show GRIN2B Antibodies) NMDA receptors via NRG2 (show NRG2 Antibodies)/ErbB4 signaling.

  5. ERBB4 overexpression potentiates Mesenchymal stem cell survival in the infarcted heart, enhances NRG1 (show NRG1 Antibodies) generation to restore the declining NRG1 (show NRG1 Antibodies) in the infarcted region and stimulates cardiomyocyte division.

  6. The observations of this study indicated that NRG1 (show NRG1 Antibodies)-ErbB4 signaling is critical to maintaining GABAergic activity in the amygdala and thus to modulating anxiety-like behaviors.

  7. Study shows that Cdk5 (show CDK5 Antibodies) and its activator p35 (show CDK5R1 Antibodies) control the tangential migration of interneurons toward and within the cerebral cortex by modulating the critical neurodevelopmental signaling pathway, ErbB4/phosphatidylinositol 3-kinase

  8. Although ERBB4 is dispensable for naive ERBB2 (show ERBB2 Antibodies)+ breast cancer cells, it may play a key role in the survival of ERBB2 (show ERBB2 Antibodies)+ cancer cells after they develop resistance to ERBB2 (show ERBB2 Antibodies) inhibitors, lapatinib and trastuzumab.

  9. In the current study, we demonstrated that ErbB4 deletion in cpk mice, a murine autosomal recessive polycystic kidney disease model, promoted cyst formation and accelerated renal function decline.

  10. the ErbB4 receptor tyrosine kinase promotes seminiferous tubule development by controlling Sertoli cell and germ cell adhesion

Human V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) interaction partners

  1. The connections of EGFR (show EGFR Antibodies) and ERBB4 signaling with SREBP-2 (show SREBF2 Antibodies)-regulated cholesterol metabolism are likely to be important in ERBB (show EGFR Antibodies)-regulated developmental processes and may contribute to metabolic remodeling in ERBB (show EGFR Antibodies)-driven cancers.

  2. nuclear HER4 seem to be co-located with estrogen receptors, however, we did not find support for overall HER4 expression in independently predicting response of tamoxifen treatment in breast cancer

  3. while transcript and protein levels of EGFR (show EGFR Antibodies) and ErbB2 (show ERBB2 Antibodies) were up-regulated or unaffected, respectively, hepatitis c virus induced a substantial reduction of ErbB3 (show ERBB3 Antibodies) and ErbB4 expression.

  4. the presence of activating driver mutations of ERBB4 in non-small cell lung cancer

  5. A combination of miRNAs induced via endothelial coculture improved embryonic-stem-cell-derived cardiomyocytes maturity, in part through suppression of ErbB4 signaling.

  6. NRG1 (show NRG1 Antibodies) promotes the proliferation and migration of coronary artery smooth muscle cells by enhancing the phosphorylation of ErbB2 (show ERBB2 Antibodies), ErbB3 (show ERBB3 Antibodies) and ErbB4.

  7. Identification of a new subclass of ALK (show ALK Antibodies)-negative Anaplastic large-cell lymphoma characterized by aberrant expression of ERBB4-truncated transcripts carrying intronic 5' untranslated regions.

  8. In this study, we developed an anti-ErbB4 mAb (clone P6-1) that suppresses NRG-dependent activation of ErbB4 and examined its effect on breast cancer cell proliferation in the extracellular matrix.

  9. Dysregulated ErbB4splicing in schizophreniamay contribute to lower activity of parvalbumin (show PVALB Antibodies) interneurons and an activity-dependent down-regulation of parvalbumin (show PVALB Antibodies) expression.

  10. NRG4 (show NRG4 Antibodies) and its receptor ErbB4 are present in human breast milk and developing human intestine, respectively. Thus, NRG4 (show NRG4 Antibodies)-ErbB4 signaling may be a novel pathway for therapeutic intervention or prevention in NEC.

ERBB4 Antigen Profile

Antigen Summary

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Alternative names and synonyms associated with ERBB4

  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (ERBB4) antibody
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4a (avian) (erbb4a) antibody
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (erbb4) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (erbb4) antibody
  • receptor tyrosine-protein kinase ErbB-4 (Tsp_13582) antibody
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (ERBB4) antibody
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (Erbb4) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 4 (Erbb4) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (ERBB4) antibody
  • c-erbB-4 antibody
  • erbb4 antibody
  • HER4 antibody
  • p180erbB4 antibody
  • si:ch211-227n20.1 antibody

Protein level used designations for ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) , erbb4c , receptor tyrosine-protein kinase erbB-4 , v-erb-a erythroblastic leukemia viral oncogene homolog 4 , receptor tyrosine-protein kinase erbB-4-like , receptor tyrosine kinase ErbB4 , receptor tyrosine-protein kinase ErbB-4 , ovarian receptor tyrosine kinase erbB4 precusor , receptor tyrosine kinase , avian erythroblastosis oncogene B 4 , proto-oncogene-like protein c-ErbB-4 , c-erbB-4 , avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4 , tyrosine kinase-type cell surface receptor HER4

GENE ID SPECIES
459919 Pan troglodytes
693341 Macaca mulatta
100077353 Ornithorhynchus anatinus
100007677 Danio rerio
100014865 Monodelphis domestica
100154104 Sus scrofa
100470612 Ailuropoda melanoleuca
100558986 Anolis carolinensis
100598496 Nomascus leucogenys
724070 Xenopus laevis
10900432 Trichinella spiralis
395671 Gallus gallus
13869 Mus musculus
488508 Canis lupus familiaris
100050182 Equus caballus
100009328 Oryctolagus cuniculus
59323 Rattus norvegicus
2066 Homo sapiens
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