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anti-Human ERBB4 antibody for Enzyme Immunoassay

Recommended ERBB4 Antibody (supplied by: Log in to see )

Antigen
V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
  • erbb4
  • si:ch211-227n20.1
  • Her4
  • c-erbB-4
  • HER4
  • p180erbB4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4a (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
  • receptor tyrosine-protein kinase ErbB-4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 4
  • ERBB4
  • erbb4a
  • erbb4
  • Tsp_13582
  • Erbb4
Epitope
pTyr1188
55
32
31
30
21
20
19
17
15
15
13
13
11
7
6
5
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
376
181
146
12
10
7
7
6
5
4
3
3
3
2
2
2
1
Host
Rabbit
292
87
1
Clonality
Polyclonal
Conjugate
This ERBB4 antibody is un-conjugated
20
18
17
15
11
10
8
8
6
6
6
5
5
5
5
5
5
4
3
3
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
204
142
123
84
68
53
30
23
11
5
2
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN358140
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN359846 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
1 ABIN358139 EIA IHC (p) WB Rabbit Ig pTyr1162 Log in to see Polyclonal 1

Top referenced anti-ERBB4 antibody for Enzyme Immunoassay

  • Human Polyclonal ERBB4 Primary Antibody for EIA, IHC (p) - ABIN359846 (5 Publications): Williams, Trout, Gallo, Pitfield, Bryant, Penington, Riese: A constitutively active ErbB4 mutant inhibits drug-resistant colony formation by the DU-145 and PC-3 human prostate tumor cell lines. in Cancer letters 2003 (PubMed)

  • Human Polyclonal ERBB4 Primary Antibody for EIA, IHC (p) - ABIN358140 (5 Publications): Tanimura, Nakago, Murakoshi, Takekida, Moriyama, Matsuo, Hashimoto, Maruo: Changes in the expression and cytological localization of betacellulin and its receptors (ErbB-1 and ErbB-4) in the trophoblasts in human placenta over the course of pregnancy. in European journal of endocrinology / European Federation of Endocrine Societies 2004 (PubMed)

  • Human Polyclonal ERBB4 Primary Antibody for EIA, IHC (p) - ABIN358139 (1 Publications): Burns, Li, Cheney, Ou, Franlin-Pfeifer, Kuklin, Zhang: Choice of fixative is crucial to successful immunohistochemical detection of phosphoproteins in paraffin-embedded tumor tissues. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 (PubMed)

Similar anti-ERBB4 Antibodies

Application / Reactivity Human
Blocking Antibody (Inhibition) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies
ELISA 119 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 53 Antibodies
Functional Studies (Func) 2 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 11 Antibodies
Immunofluorescence (IF) 30 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 68 Antibodies
Immunohistochemistry (IHC) 142 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 85 Antibodies
Immunoprecipitation (IP) 23 Antibodies
Neutralization (Neut) 1 Antibodies

General

Antigen V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
Epitope pTyr1188
(55), (32), (31), (30), (21), (20), (19), (17), (15), (15), (13), (13), (11), (7), (6), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(376), (181), (146), (12), (10), (7), (7), (6), (5), (4), (3), (3), (3), (2), (2), (2), (1)
Host Rabbit
(292), (87), (1)
Clonality
Polyclonal
Conjugate This ERBB4 antibody is un-conjugated
(20), (18), (17), (15), (11), (10), (8), (8), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(204), (142), (123), (84), (68), (53), (30), (23), (11), (5), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-ERBB4 Antibody

Target Details ERBB4 Application Details Handling References for anti-ERBB4 Antibody (ABIN358140) Images
Specificity This antibody detects HER4 pTyr1188.
Purification Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1188 of human HER4.
Isotype Ig

Target Details ERBB4

Product Details anti-ERBB4 Antibody Application Details Handling References for anti-ERBB4 Antibody (ABIN358140) Images back to top
Antigen
Alternative Name ERBB4 / HER4 (ERBB4 Antibody Abstract)
Background The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2, and ERBB3. It encodes a receptor for NDF/heregulin.Synonyms: HER-4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell surface receptor HER4, c-ErbB-4, p180erbB4
Molecular Weight 146808 Da
Gene ID 2066, 9606
UniProt Q15303
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-ERBB4 Antibody Target Details ERBB4 Handling References for anti-ERBB4 Antibody (ABIN358140) Images back to top
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details References for anti-ERBB4 Antibody (ABIN358140) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-ERBB4 Antibody (ABIN358140)

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details Handling Images back to top
Background publications

Tanimura, Nakago, Murakoshi, Takekida, Moriyama, Matsuo, Hashimoto, Maruo: "Changes in the expression and cytological localization of betacellulin and its receptors (ErbB-1 and ErbB-4) in the trophoblasts in human placenta over the course of pregnancy." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 151, Issue 1, pp. 93-101, 2004

Hughes, Thomas, Giordano, Baker, McDonagh: "Cell surface expression of epidermal growth factor receptor and Her-2 with nuclear expression of Her-4 in primary osteosarcoma." in: Cancer research, Vol. 64, Issue 6, pp. 2047-53, 2004

Cheng, Tikhomirov, Zhou, Carpenter: "Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38421-7, 2003

Chaudhury, Gerecke, Wyss, Morgan, Gordon, Carroll: "Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease." in: Journal of neuropathology and experimental neurology, Vol. 62, Issue 1, pp. 42-54, 2003

Komuro, Nagai, Navin, Sudol: "WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 33334-41, 2003

Images

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details Handling References for anti-ERBB4 Antibody (ABIN358140) back to top
Supplier Images
 image for anti-ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (pTyr1188) (ABIN358140) anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1188) antibody
 image for anti-ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (pTyr1188) (ABIN358140) anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1188) antibody (Image 2)