anti-Human ERBB4 antibody for Western Blotting

Recommended ERBB4 Antibody (supplied by: Log in to see )

Antigen
V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
  • erbb4
  • si:ch211-227n20.1
  • Her4
  • c-erbB-4
  • HER4
  • p180erbB4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4a (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
  • receptor tyrosine-protein kinase ErbB-4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 4
  • ERBB4
  • erbb4a
  • erbb4
  • Tsp_13582
  • Erbb4
Epitope
AA 25-55, N-Term
55
37
37
33
24
21
20
19
17
15
15
11
7
6
6
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
403
179
145
12
9
6
6
6
5
3
3
3
2
2
2
1
1
Host
Rabbit
301
106
2
Clonality
Polyclonal
Conjugate
This ERBB4 antibody is un-conjugated
21
18
17
16
12
10
10
10
8
8
8
5
5
5
5
5
5
5
5
3
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
212
144
126
91
70
68
28
23
15
6
5
3
2
1
1
Options
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Catalog No. ABIN391950
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN2704881 IC IF IHC WB Rabbit C-Term, pTyr1284 Log in to see Polyclonal
3.2182703 ABIN2704882 IC IF IHC WB Rabbit C-Term Log in to see Polyclonal
3.2182703 ABIN359846 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
3.2182703 ABIN391951 IHC (p) WB Rabbit Ig AA 1276-1308, C-Term Log in to see Polyclonal 3
3.2182703 ABIN251106 CyTOF FACS ICC IF IHC IP WB Mouse IgG2b AA 1249-1264 Log in to see HFR1 1
3.2182703 ABIN267015 FACS ICC IF IP WB Mouse IgG1 Log in to see H4-77-16 (Ab77) 1
3.2182703 ABIN1531611 IF IHC ELISA WB Rabbit IgG AA 1250-1299, pTyr1284 Log in to see Polyclonal
3.2182703 ABIN443062 ICC IF IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 1
3.2182703 ABIN3044100 WB Rabbit IgG AA 35-51, N-Term Log in to see Polyclonal
3.2182703 ABIN126796 WB Mouse IgG pTyr1242 Log in to see 4C6
3.2182703 ABIN126795 WB Mouse IgG1 AA 1230-1250 Log in to see 6C5
3.2182703 ABIN4309317 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
3.2182703 ABIN3023535 WB Rabbit IgG pTyr1284 Log in to see Polyclonal
3.2182703 ABIN1870170 WB Rabbit IgG pTyr1284 Log in to see Polyclonal
3.2182703 ABIN3032774 ELISA WB Rabbit Ig Fraction AA 1165-1199, C-Term Log in to see Polyclonal
3.2182703 ABIN3029487 IF IHC ELISA WB Rabbit Ig Fraction pTyr1162 Log in to see Polyclonal
3.2182703 ABIN4903886 WB Rabbit IgG Log in to see Polyclonal
3.2182703 ABIN443932 IHC (p) IHC WB Rabbit C-Term Log in to see Polyclonal
3.2182703 ABIN1536665 WB Rabbit Ig AA 1141-1166, C-Term Log in to see Polyclonal
3.2182703 ABIN3029488 IHC ELISA WB Rabbit Ig Fraction pTyr1188 Log in to see Polyclonal

General

Antigen V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
Epitope AA 25-55, N-Term
(55), (37), (37), (33), (24), (21), (20), (19), (17), (15), (15), (11), (7), (6), (6), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(403), (179), (145), (12), (9), (6), (6), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(301), (106), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This ERBB4 antibody is un-conjugated
(21), (18), (17), (16), (12), (10), (10), (10), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(212), (144), (126), (91), (70), (68), (28), (23), (15), (6), (5), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-ERBB4 Antibody

Target Details ERBB4 Application Details Handling References for anti-ERBB4 antibody (ABIN391950) Images
Specificity This ErbB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33~63 amino acids from the N-terminal region of human ErbB4.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This ERBB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 AA from the N-terminal region of human ERBB4.
Clone RB01469
Isotype Ig

Target Details ERBB4

Product Details anti-ERBB4 Antibody Application Details Handling References for anti-ERBB4 antibody (ABIN391950) Images back to top
Antigen
Alternative Name ErbB4 (ERBB4 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Synonyms: Tyrosine kinase-type cell surface receptor HER4 , HER4
Molecular Weight 146807 DA
Gene ID 2066
UniProt Q15303
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-ERBB4 Antibody Target Details ERBB4 Handling References for anti-ERBB4 antibody (ABIN391950) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only

Handling

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details References for anti-ERBB4 antibody (ABIN391950) Images back to top
Format Liquid
Concentration 1.71 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-ERBB4 antibody (ABIN391950)

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details Handling Images back to top
Product cited in:

Xu, Watanabe, Iso, Koba, Sakai, Nagashima, Arita, Hongo, Ota, Kobayashi, Miyazaki, Hirano: "Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis." in: Circulation research, Vol. 105, Issue 5, pp. 500-10, 2009

Background publications

Cheng, Tikhomirov, Zhou, Carpenter: "Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38421-7, 2003

Komuro, Nagai, Navin, Sudol: "WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 33334-41, 2003

Ni, Yuan, Carpenter: "Role of the ErbB-4 carboxyl terminus in gamma-secretase cleavage." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4561-5, 2003

Images

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details Handling References for anti-ERBB4 antibody (ABIN391950) back to top
Supplier Images
Western Blotting (WB) image for anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 25-55), (N-Term) antibody (ABIN391950) Western blot analysis of anti-ErbB4 Pab (ABIN391950) in HL60 cell lysate. ErbB4 (Arro...
Immunohistochemistry (IHC) image for anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 25-55), (N-Term) antibody (ABIN391950) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...