anti-Mouse (Murine) ERBB4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended ERBB4 Antibody (supplied by: Log in to see )

Antigen
V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
  • erbb4
  • si:ch211-227n20.1
  • Her4
  • c-erbB-4
  • HER4
  • p180erbB4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4a (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
  • receptor tyrosine-protein kinase ErbB-4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 4
  • ERBB4
  • erbb4a
  • erbb4
  • Tsp_13582
  • Erbb4
Epitope
AA 460-510
56
33
31
31
21
21
19
17
15
15
13
13
11
7
6
6
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
391
179
145
12
9
6
6
6
5
3
3
3
2
2
2
1
1
Host
Rabbit
299
97
1
Clonality
Polyclonal
Conjugate
This ERBB4 antibody is un-conjugated
21
18
17
15
11
10
9
9
7
7
7
5
5
5
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
212
143
126
91
67
59
27
24
13
5
3
2
2
2
1
1
Options
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Catalog No. ABIN1714916
$ 295.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.4040785 ABIN498233 IF IHC (p) Rabbit Log in to see Polyclonal
13.4040785 ABIN213400 IHC (p) Rabbit Internal Region Log in to see Polyclonal
13.4040785 ABIN446812 ICC IF IHC (p) IHC Rabbit Log in to see Polyclonal
13.4040785 ABIN4309316 IHC (p) Rabbit Log in to see Polyclonal
1 ABIN737436 FACS IF (p) IHC (p) Rabbit IgG AA 1210-1260 Log in to see Polyclonal 1
1 ABIN443062 ICC IF IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 1
1 ABIN2888849 IF IHC (p) ELISA Rabbit IgG AA 1250-1299 Log in to see Polyclonal
1 ABIN1048578 IHC (p) Rabbit Internal Region Log in to see Polyclonal
1 ABIN800667 IHC (p) HRP Rabbit IgG pTyr1162 Log in to see Polyclonal
1 ABIN800682 IHC (p) HRP Rabbit IgG pTyr1188 Log in to see Polyclonal
1 ABIN1712442 IHC (p) WB HRP Rabbit IgG pTyr1258 Log in to see Polyclonal
1 ABIN743072 IHC (p) WB HRP Rabbit IgG pTyr1284 Log in to see Polyclonal
1 ABIN1712584 IHC (p) WB HRP Rabbit IgG pTyr1056 Log in to see Polyclonal
1 ABIN800660 IHC (p) Biotin Rabbit IgG pTyr1162 Log in to see Polyclonal
1 ABIN800675 IHC (p) Biotin Rabbit IgG pTyr1188 Log in to see Polyclonal
1 ABIN1701425 IHC (p) WB Biotin Rabbit IgG pTyr1258 Log in to see Polyclonal
1 ABIN743065 IHC (p) WB Biotin Rabbit IgG pTyr1284 Log in to see Polyclonal
1 ABIN1701567 IHC (p) WB Biotin Rabbit IgG pTyr1056 Log in to see Polyclonal
1 ABIN800658 IF (p) IHC (p) Rabbit IgG pTyr1162 Log in to see Polyclonal
1 ABIN800673 IF (p) IHC (p) Rabbit IgG pTyr1188 Log in to see Polyclonal

Top referenced anti-ERBB4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-ERBB4 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies 4 Antibodies 4 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies 1 Antibodies
Western Blotting (WB) 211 Antibodies 75 Antibodies 48 Antibodies
Neutralization (Neut) 1 Antibodies
Immunoprecipitation (IP) 24 Antibodies 15 Antibodies 13 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 92 Antibodies 48 Antibodies 27 Antibodies
Immunohistochemistry (IHC) 143 Antibodies 45 Antibodies 29 Antibodies

General

Antigen V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) Antibodies
Epitope AA 460-510
(56), (33), (31), (31), (21), (21), (19), (17), (15), (15), (13), (13), (11), (7), (6), (6), (6), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(391), (179), (145), (12), (9), (6), (6), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(299), (97), (1)
Clonality
Polyclonal
Conjugate This ERBB4 antibody is un-conjugated
(21), (18), (17), (15), (11), (10), (9), (9), (7), (7), (7), (5), (5), (5), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(212), (143), (126), (91), (67), (59), (27), (24), (13), (5), (3), (2), (2), (2), (1), (1)
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Product Details anti-ERBB4 Antibody

Target Details ERBB4 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human HER4/ErbB4
Isotype IgG

Target Details ERBB4

Product Details anti-ERBB4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name HER4/ErbB4 (ERBB4 Antibody Abstract)
Background

Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. Required for normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. Required for mammary gland differentiation, induction of milk proteins and lactation. Acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. Ligand specificity and signaling is modulated by alternative splicing, proteolytic processing, and by the formation of heterodimers with other ERBB family members, thereby creating multiple combinations of intracellular phosphotyrosines that trigger ligand- and context-specific cellular responses. Mediates phosphorylation of SHC1 and activation of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1. Isoform JM-A CYT-1 and isoform JM-B CYT-1 phosphorylate PIK3R1, leading to the activation of phosphatidylinositol 3-kinase and AKT1 and protect cells against apoptosis. Isoform JM-A CYT-1 and isoform JM-B CYT-1 mediate reorganization of the actin cytoskeleton and promote cell migration in response to NRG1. Isoform JM-A CYT-2 and isoform JM-B CYT-2 lack the phosphotyrosine that mediates interaction with PIK3R1, and hence do not phosphorylate PIK3R1, do not protect cells against apoptosis, and do not promote reorganization of the actin cytoskeleton and cell migration.

Subcellular location: Extracellular

Synonyms: HER4, ALS19, p180erbB4, Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-like protein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4, ERBB4

Gene ID 2066
UniProt Q15303
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-ERBB4 Antibody Target Details ERBB4 Handling Images back to top
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-ERBB4 Antibody Target Details ERBB4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (AA 460-510) (ABIN1714916) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-HER4/ErbB4 Po...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-ERBB4 antibody (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (AA 460-510) (ABIN1714916) Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-HER4/ErbB4 P...