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|Antigen||Fibroblast Growth Factor 10 (FGF10) Antibodies|
|Conjugate||This FGF10 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|3 references available|
|Supplier||Log in to see|
Product Details anti-FGF10 AntibodyTarget Details FGF10 Application Details Handling References for anti-FGF10 antibody (ABIN360398) Images
|Specificity||This antibody reacts to FGF10.|
|Purification||Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGF10.|
Target Details FGF10Product Details anti-FGF10 Antibody Application Details Handling References for anti-FGF10 antibody (ABIN360398) Images back to top
|Alternative Name||FGF10 (FGF10 Antibody Abstract)|
|Background||FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.Synonyms: FGF-10, Fibroblast growth factor 10, KGF2, Keratinocyte growth factor 2|
|Gene ID||2255, 9606|
|Research Area||Cancer, Growth Factors, Angiogenesis|
|Pathways||RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus|
Application DetailsProduct Details anti-FGF10 Antibody Target Details FGF10 Handling References for anti-FGF10 antibody (ABIN360398) Images back to top
ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FGF10 Antibody Target Details FGF10 Application Details References for anti-FGF10 antibody (ABIN360398) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-FGF10 antibody (ABIN360398)Product Details anti-FGF10 Antibody Target Details FGF10 Application Details Handling Images back to top
Nomura, Yoshitomi, Takano, Shida, Kobayashi, Ohtsuka, Kimura, Shimizu, Yoshidome, Kato, Miyazaki: "FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer." in: British journal of cancer, Vol. 99, Issue 2, pp. 305-13, 2008
Belleudi, Leone, Nobili, Raffa, Francescangeli, Maggio, Morrone, Marchese, Torrisi: "Keratinocyte growth factor receptor ligands target the receptor to different intracellular pathways." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 12, pp. 1854-72, 2007
Igarashi, Finch, Aaronson: "Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7)." in: The Journal of biological chemistry, Vol. 273, Issue 21, pp. 13230-5, 1998
ImagesProduct Details anti-FGF10 Antibody Target Details FGF10 Application Details Handling References for anti-FGF10 antibody (ABIN360398) back to top