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|Application / Reactivity||Human|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|Flow Cytometry (FACS)||36 Antibodies|
|Immunochromatography (IC)||1 Antibodies|
|Immunocytochemistry (ICC)||3 Antibodies|
|Immunofluorescence (IF)||15 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||2 Antibodies|
|Immunohistochemistry (IHC)||27 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||13 Antibodies|
|Immunoprecipitation (IP)||3 Antibodies|
|Radioimmunoassay (RIA)||2 Antibodies|
|Western Blotting (WB)||115 Antibodies|
|Antigen||Fibroblast Growth Factor 21 (FGF21) Antibodies|
|Epitope||AA 30-210 Alternatives|
|Conjugate||This FGF21 antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-FGF21 AntibodyTarget Details FGF21 Application Details Handling References for anti-FGF21 Antibody (ABIN395569) Images
|Specificity||FGF21 (AAH18404, 30 a.a. ~ 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Purification||This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||FGF21 (AAH18404, 30 a.a. ~ 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K|
Target Details FGF21Product Details anti-FGF21 Antibody Application Details Handling References for anti-FGF21 Antibody (ABIN395569) Images back to top
|Alternative Name||FGF21 (FGF21 Antibody Abstract)|
|Background||Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1|
|Molecular Weight||22300 DA|
|Research Area||Cancer, Cell Structure|
Application DetailsProduct Details anti-FGF21 Antibody Target Details FGF21 Handling References for anti-FGF21 Antibody (ABIN395569) Images back to top
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml|
Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FGF21 Antibody Target Details FGF21 Application Details References for anti-FGF21 Antibody (ABIN395569) Images back to top
|Buffer||PBS with 0.09% (w/v) sodium azide.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
|Storage Comment||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles|
|Expiry Date||6 months|
References for anti-FGF21 Antibody (ABIN395569)Product Details anti-FGF21 Antibody Target Details FGF21 Application Details Handling Images back to top
Kaess, Barnes, Stark et al.: "FGF21 signalling pathway and metabolic traits - genetic association analysis." in: European journal of human genetics : EJHG, Vol. 18, Issue 12, pp. 1344-8, 2010 (PubMed).
Cuevas-Ramos, Almeda-Valdes, Gómez-Pérez et al.: "Daily physical activity, fasting glucose, uric acid, and body mass index are independent factors associated with serum fibroblast growth factor 21 levels." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 163, Issue 3, pp. 469-77, 2010 (PubMed).
Dushay, Chui, Gopalakrishnan et al.: "Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease." in: Gastroenterology, Vol. 139, Issue 2, pp. 456-63, 2010 (PubMed).
Wang, Solt, Burris: "Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 15668-73, 2010 (PubMed).
Fazeli, Misra, Goldstein et al.: "Fibroblast growth factor-21 may mediate growth hormone resistance in anorexia nervosa." in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 1, pp. 369-74, 2010 (PubMed).
ImagesProduct Details anti-FGF21 Antibody Target Details FGF21 Application Details Handling References for anti-FGF21 Antibody (ABIN395569) back to top