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Human FGF21 Primary Antibody for ELISA - ABIN1672889
Nishimura, Nakatake, Konishi, Itoh: Identification of a novel FGF, FGF-21, preferentially expressed in the liver. in Biochimica et biophysica acta 2000
Show all 2 references for ABIN1672889
Mouse (Murine) FGF21 Primary Antibody for ELISA - ABIN2859244
Liu, Pan, Chen, Yang, Zhao, Jia, Zhu, Zhang, Gao, Li, Han, Duan: Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy. in Scientific reports 2015
Cow (Bovine) FGF21 Primary Antibody for ELISA - ABIN1000145
Farney, Mamedova, Coetzee, KuKanich, Sordillo, Stoakes, Minton, Hollis, Bradford: Anti-inflammatory salicylate treatment alters the metabolic adaptations to lactation in dairy cattle. in American journal of physiology. Regulatory, integrative and comparative physiology 2013
Pig (Porcine) FGF21 Primary Antibody for ELISA - ABIN649220
Varady, Ringseis, Eder: Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs. in Lipids in health and disease 2012
FGF21-PXR (show NR1I2 ELISA Kits) signaling pathway may be involved in decreased hepatic CYP3A4 (show CYP3A4 ELISA Kits) metabolic activity in Nonalcoholic fatty liver disease.
data show that AHR (show AHR ELISA Kits) contributes to hepatic energy homeostasis, partly through the regulation of FGF21 expression and signaling.
Chronic stimulation of PPARalpha (show PPARA ELISA Kits) may suppress the autophagy capacity in the liver as a result of reduced content of a number of autophagy-associated proteins independent of FGF21.
Study compared the diagnostic utility of GDF-15 (show GDF15 ELISA Kits) with FGF-21 in an adult mitochondrial disease cohort. GDF-15 (show GDF15 ELISA Kits) outperforms FGF-21 as an indicator of mitochondrial diseases. GDF-15 (show GDF15 ELISA Kits) is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 seems to be more indicative of mitochondrial disease when muscle manifestations are present
The results suggest that increased circulating CK-18 (show KRT18 ELISA Kits) and FGF-21 are associated with Nonalcoholic Fatty Liver Disease and may be used for initial assessment, but not enough
Plasma FGF21 concentrations are increased in prediabetic first-degree relatives of patients with type 2 diabetes mellitus and that there is a significant association between FGF21 and obesity and insulin (show INS ELISA Kits) sensitivity.
This review will give a comprehensive understanding of the underlying role of FGF21 and its possible interaction with other molecules in Diabetic nephropathy
FGF21 is a novel surrogate diagnostic biomarker in initial stages of T2 Diabetic retinopathy (particularly with FGF21 values above 135.5pg/mL).
Accumulation of adipose tissue in the RS is related with the visceral adipose amount, KIM-1 (show HAVCR1 ELISA Kits) and FGF-21 concentration increase in the blood serum.
The results showed that the FGF21 promoter contains three response elements for ATF4 (show ATF4 ELISA Kits), suggesting that FGF21 is a sensitive target of ATF4 (show ATF4 ELISA Kits).
RESULTS: The results showed that serum FGF-21 levels were significantly higher in both groups treated with a controlled-energy diet, while FGF-21 levels in both groups treated with moderate-energy diet were low.
liver-derived FGF21 regulates the use of lipid reserves during lactation via focal actions on liver and white adipose tissue.
this study shows that FGF21 exerts an anti-inflammatory effect mainly via enhancing Nrf2 (show NFE2L2 ELISA Kits)-mediated anti-oxidant capacity and suppressing NF-kappaB (show NFKB1 ELISA Kits) signaling pathway
FGF21 corrects multiple metabolic parameters on NAFLD (show TSC2 ELISA Kits) in vitro and in vivo by inducing autophagy.
these data reveal a previously unidentified role for FGF21 on bile acid metabolism and may be relevant to understand the effects of FGF21 analogs in clinical studies.
These results suggest for the first time that FF prevents the development of diabetic nephropathy via up-regulating FGF21 and stimulating PI3K/Akt (show AKT1 ELISA Kits)/GSK-3b/Fyn (show FYN ELISA Kits)-mediated activation of the Nrf2 (show NFE2L2 ELISA Kits) pathway.
The requirement of fibroblast growth factor 21 for the metabolic actions of hepatic cJun (show JUN ELISA Kits) NH2-terminal kinase provides a mechanism for metabolic regulation by the JNK (show MAPK8 ELISA Kits)-signaling pathway in the liver.
These findings establish Rev-erbalpha (show NR1D1 ELISA Kits) as a specific modulator of FGF21 signaling in adipose tissue.
the liver regulates carbohydrate intake through production of the hepatokine fibroblast growth factor 21 (FGF21), which markedly suppresses consumption of simple sugars, but not complex carbohydrates, proteins, or lipids.
FGF21 administration markedly reduces sweet and alcohol preference in mice and sweet preference in cynomolgus monkeys.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
fibroblast growth factor 21