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Browse our FGF21 Proteins (FGF21)

Full name:
Fibroblast Growth Factor 21 Proteins (FGF21)
On www.antibodies-online.com are 76 Fibroblast Growth Factor 21 (FGF21) Proteins from 17 different suppliers available. Additionally we are shipping FGF21 Antibodies (199) and FGF21 Kits (82) and many more products for this protein. A total of 378 FGF21 products are currently listed.
Synonyms:
FGF21
list all proteins Gene Name GeneID UniProt
FGF21 26291 Q9NSA1
FGF21 56636 Q9JJN1
FGF21 170580  

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FGF21 Proteins (FGF21) by Origin

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Top referenced FGF21 Proteins

  1. Human FGF21 Protein expressed in Escherichia coli (E. coli) - ABIN2666735 : Bookout, de Groot, Owen, Lee, Gautron, Lawrence, Ding, Elmquist, Takahashi, Mangelsdorf, Kliewer: FGF21 regulates metabolism and circadian behavior by acting on the nervous system. in Nature medicine 2013 (PubMed)
    Show all 6 references for ABIN2666735

  2. Mouse (Murine) FGF21 Protein expressed in Human Cells - ABIN2007779 : Arner, Pettersson, Mitchell, Dunbar, Kharitonenkov, Rydén: FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity. in FEBS letters 2008 (PubMed)
    Show all 3 references for ABIN2007779

  3. Human FGF21 Protein expressed in Escherichia coli (E. coli) - ABIN2003596 : Micanovic, Raches, Dunbar, Driver, Bina, Dickinson, Kharitonenkov: Different roles of N- and C- termini in the functional activity of FGF21. in Journal of cellular physiology 2009 (PubMed)
    Show all 2 references for ABIN2003596

  4. Human FGF21 Protein expressed in Escherichia coli (E. coli) - ABIN666738 : Dostálová, Haluzíková, Haluzík: Fibroblast growth factor 21: a novel metabolic regulator with potential therapeutic properties in obesity/type 2 diabetes mellitus. in Physiological research / Academia Scientiarum Bohemoslovaca 2009 (PubMed)
    Show all 2 references for ABIN666738

  5. Mouse (Murine) FGF21 Protein expressed in Escherichia coli (E. coli) - ABIN1888798 : Stone, Wanders, Orgeron, Cortez, Gettys: Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice. in Diabetes 2014 (PubMed)

More Proteins for FGF21 Interaction Partners

Human Fibroblast Growth Factor 21 (FGF21) interaction partners

  1. miR (show MLXIP Proteins)-149 could negatively regulate the protein expression level of FGF-21.

  2. As a biomarker for diabetes prediction, serum FGF21 appeared to be superior to other adipokines and, on its own, could be considered as an alternative to the oral glucose tolerance test.

  3. Serum FGF21 rises significantly in humans with acute pancreatitis. The pancreas may be contributing to increased FGF21 levels following injury and FGF21 may play a role in the recovery process.

  4. These findings reveal an iNKT cell-FGF21 axis that defines a new immune-mediated pathway that could be targeted for glycemic control and weight regulation.

  5. have identified fibroblast activation protein (FAP) as the endopeptidase responsible for this site-specific cleavage of human FGF21 (hFGF21), and propose that inhibition of FAP may be a therapeutic strategy to increase endogenous levels of active FGF21.

  6. NS5ATP6 reduces the promoter activity of FGF21. NS5ATP6 may regulate FGF21 expression via miR (show MLXIP Proteins)-577. NS5ATP6 regulates the intracellular triglyceride level via FGF21, and independently of SIRT1 (show SIRT1 Proteins) and SREBP1 (show SREBF1 Proteins).

  7. Study provides Class III evidence that elevated S-FGF21 accurately distinguishes patients with mitochondrial myopathies from patients with other conditions, and FGF21 and GDF15 (show GDF15 Proteins) mitochondrial myopathy from other myopathies.

  8. FGF21-PXR (show NR1I2 Proteins) signaling pathway may be involved in decreased hepatic CYP3A4 (show CYP3A4 Proteins) metabolic activity in Nonalcoholic fatty liver disease.

  9. data show that AHR (show AHR Proteins) contributes to hepatic energy homeostasis, partly through the regulation of FGF21 expression and signaling.

  10. Chronic stimulation of PPARalpha (show PPARA Proteins) may suppress the autophagy capacity in the liver as a result of reduced content of a number of autophagy-associated proteins independent of FGF21.

Cow (Bovine) Fibroblast Growth Factor 21 (FGF21) interaction partners

  1. The present study shows that expression of the FGF21 gene is strongly up-regulated during the transition period; the up-regulation of FGF21 might play an important role in the adaptation of liver metabolism during early lactation in dairy cows such as in other species.

  2. RESULTS: The results showed that serum FGF-21 levels were significantly higher in both groups treated with a controlled-energy diet, while FGF-21 levels in both groups treated with moderate-energy diet were low.

  3. liver-derived FGF21 regulates the use of lipid reserves during lactation via focal actions on liver and white adipose tissue.

Mouse (Murine) Fibroblast Growth Factor 21 (FGF21) interaction partners

  1. These findings reveal an iNKT cell-FGF21 axis that defines a new immune-mediated pathway that could be targeted for glycemic control and weight regulation.

  2. the metabolic outcomes associated with elevated FGF21 depend on the nutritional context, differing according to whether the animal is in a state of under- or overfeeding.

  3. These findings indicate that FGF21 is crucial for the fenofibrate-mediated improvement of whole body glucose metabolism in obese mice via the amelioration of WAT dysfunctions.

  4. These new findings reveal that the FGF21-betaKlotho-FGFR1 signaling axis plays roles in maintaining phospholipid homeostasis and the dynamic functions of the lipid droplet, whereas protecting against ER stress, and suggest a potential link of phospholipid biosynthesis, lipid droplet dynamics, ER stress, and energy homeostasis in adipose tissue coordinated by this signaling axis.

  5. CYP2A5 protects against the development of alcoholic fatty liver disease, and the PPARalpha-FGF21 axis contributes to the protective effects of CYP2A5 on alcoholic fatty liver disease.

  6. Heme-Regulated eIF2alpha (show EIF2A Proteins) Kinase Modulates Hepatic FGF21 and Is Activated by PPARbeta (show PPARD Proteins)/delta Deficiency. Findings suggest that HRI (show EIF2AK1 Proteins) is a potential target for regulating hepatic FGF21 levels.

  7. FGF21 promotes myoblast differentiation and serves as a switch of molecular transformation from anaerobic myofibers to aerobic myofibers via the FGF21-SIRT1 (show SIRT1 Proteins)-AMPK (show PRKAA1 Proteins)-PGC1alpha axis.

  8. FGF21-PXR (show NR1I2 Proteins) signaling pathway may be involved in decreased hepatic CYP3A4 (show CYP3A4 Proteins) metabolic activity in Nonalcoholic fatty liver disease.

  9. data show that AHR (show AHR Proteins) contributes to hepatic energy homeostasis, partly through the regulation of FGF21 expression and signaling.

  10. this study shows that FGF21 exerts an anti-inflammatory effect mainly via enhancing Nrf2 (show NFE2L2 Proteins)-mediated anti-oxidant capacity and suppressing NF-kappaB (show NFKB1 Proteins) signaling pathway

FGF21 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.

Alternative names and synonyms associated with FGF21

  • fibroblast growth factor 21 (FGF21)
  • fibroblast growth factor 21 (fgf21)
  • fibroblast growth factor 21 (Fgf21)
  • fibroblast growth factor 21 (LOC100356340)
  • FGF21 protein

Protein level used designations for FGF21

fibroblast growth factor 21 , FGF-21

GENE ID SPECIES
468948 Pan troglodytes
718288 Macaca mulatta
724048 Danio rerio
26291 Homo sapiens
484395 Canis lupus familiaris
100302504 Sus scrofa
785576 Bos taurus
56636 Mus musculus
170580 Rattus norvegicus
100728398 Cavia porcellus
100356340 Oryctolagus cuniculus
101108510 Ovis aries
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