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anti-Human FGFR1 antibody for Western Blotting

Recommended FGFR1 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies
  • FGFR
  • fgfr
  • X1FGFR
  • XFGFR-1
  • XFGFRA2
  • bfgfr
  • cek
  • fgfr1
  • flg
  • flt-2
  • flt2
  • kal2
  • ogd
  • xfgfr1
  • CG7223
  • CT22273
  • CT39172
  • DFGF-R1
  • DFGF-R2
  • DFR-1
  • DFR1
  • DFR1/DFGF-R2
  • DPR3
  • DTRK(FR1)
  • Dfr-1
  • Dfr1
  • DmHD-38
  • Dmel\\CG7223
  • Dtk1
  • EMS2
  • FGF-R2
  • FGFR2
  • FR1
  • Fr1
  • HD-38
  • HTL/FGFR1
  • Htl
  • Tk1
  • dtk1
  • i100
  • i150
  • i79
  • j372
  • cd331
  • fgfbr
  • fgfr-1
  • hbgfr
  • n-sam
  • ach
  • cd333
  • cek2
  • fgfr-3
  • hsfgfr3ex
  • jtk4
  • BFGFR
  • CD331
  • CEK
  • FGFBR
  • FGFR-1
  • FLG
  • FLT-2
  • FLT2
  • HBGFR
  • HH2
  • KAL2
  • N-SAM
  • OGD
  • bFGF-R-1
  • AW208770
  • Eask
  • Fgfr-1
  • Flt-2
  • Hspy
  • FLG-1
  • FGFRI
  • x1fgfr
  • cb231
  • sb:cb231
  • fibroblast growth factor receptor
  • fibroblast growth factor receptor 1
  • basic fibroblast growth factor receptor 1
  • heartless
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)
  • Fibroblast growth factor receptor 1
  • fibroblast growth factor receptor 1a
  • FGFR
  • fgfr
  • fgfr1-a
  • CpipJ_CPIJ005849
  • htl
  • fgfr1
  • fgfr3
  • FGFR1
  • Fgfr1
  • fgfr1-b
  • fgfr1a
Epitope
Tyr307
64
55
52
42
42
33
29
28
27
24
22
18
18
17
17
15
11
10
10
9
9
9
8
6
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
581
220
176
15
10
9
8
4
4
3
3
2
1
1
1
Host
Rabbit
405
158
35
Clonality
Polyclonal
Conjugate
This FGFR1 antibody is un-conjugated
30
26
26
23
19
19
8
8
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
480
242
168
98
89
68
54
47
44
23
19
9
8
2
1
1
1
Supplier
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Catalog No. ABIN951300
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9590793 ABIN359853 EIA WB Rabbit Ig Tyr154 Log in to see Polyclonal 5
2.9590793 ABIN1532336 IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
2.9590793 ABIN4620445 EIA WB Rabbit Ig Tyr766 Log in to see Polyclonal 5
2.9590793 ABIN4620447 EIA WB Rabbit Ig Tyr463 Log in to see Polyclonal 5
2.9590793 ABIN4620446 EIA WB Rabbit Ig Tyr653 Log in to see Polyclonal 5
2.9590793 ABIN250616 CyTOF FACS IHC IHC (p) IP WB Mouse IgG2b Isoform beta Log in to see M17A3 1
2.9590793 ABIN250617 CyTOF FACS ICC IF IHC IHC (p) IP WB Mouse IgG1 Isoform alpha, Isoform beta Log in to see M17D10 1
2.9590793 ABIN269474 CyTOF FACS IP WB Mouse IgG1 Isoform alpha, Isoform beta Log in to see M19B2 3
2.9590793 ABIN969138 ELISA WB Mouse IgG2b AA 22-376 Log in to see 3D4F7 3
2.9590793 ABIN268017 CyTOF FACS ICC IF IHC IHC (fro) IP WB Mouse IgG2a Isoform alpha Log in to see M2F12 3
2.9590793 ABIN250368 IHC (p) IHC ELISA WB Goat C-Term Log in to see Polyclonal 1
2.9590793 ABIN1882081 FACS IF IHC (p) WB Rabbit AA 19-48, N-Term Log in to see Polyclonal 10
2.9590793 ABIN4311479 ELISA WB Goat IgG Extracellular Domain Log in to see Polyclonal 1
2.9590793 ABIN2464985 ELISA WB Goat N-Term Log in to see Polyclonal
2.9590793 ABIN1531317 IHC ELISA WB Rabbit IgG pTyr766 Log in to see Polyclonal
2.9590793 ABIN1531318 IF ELISA WB Rabbit IgG pTyr654 Log in to see Polyclonal
2.9590793 ABIN1531842 ELISA WB Rabbit IgG pTyr154 Log in to see Polyclonal
2.9590793 ABIN614919 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal
2.9590793 ABIN391960 WB Rabbit Ig AA 441-470, Tyr463 Log in to see Polyclonal
2.9590793 ABIN391962 WB Rabbit Ig AA 744-773, Tyr766 Log in to see Polyclonal

Top referenced anti-FGFR1 antibody for Western Blotting

Similar anti-FGFR1 Antibodies

Application / Reactivity Human
Blocking Peptide (BP) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 8 Antibodies
Dot Blot (DB) 19 Antibodies
ELISA 232 Antibodies
Enzyme Immunoassay (EIA) 10 Antibodies
Flow Cytometry (FACS) 89 Antibodies
Immunocytochemistry (ICC) 46 Antibodies
Immunofluorescence (IF) 54 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 44 Antibodies
Immunohistochemistry (IHC) 167 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 21 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 96 Antibodies
Immunoprecipitation (IP) 66 Antibodies
Neutralization (Neut) 1 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 472 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies
Epitope Tyr307
(64), (55), (52), (42), (42), (33), (29), (28), (27), (24), (22), (18), (18), (17), (17), (15), (11), (10), (10), (9), (9), (9), (8), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(581), (220), (176), (15), (10), (9), (8), (4), (4), (3), (3), (2), (1), (1), (1)
Host Rabbit
(405), (158), (35)
Clonality
Polyclonal
Conjugate This FGFR1 antibody is un-conjugated
(30), (26), (26), (23), (19), (19), (8), (8), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(480), (242), (168), (98), (89), (68), (54), (47), (44), (23), (19), (9), (8), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-FGFR1 Antibody

Target Details FGFR1 Application Details Handling References for anti-FGFR1 Antibody (ABIN951300) Images
Specificity This antibody reacts to FGFR1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Immunogen KLH conjugated synthetic peptide selected from the Y307 region of human FGFR1
Isotype Ig

Target Details FGFR1

Product Details anti-FGFR1 Antibody Application Details Handling References for anti-FGFR1 Antibody (ABIN951300) Images back to top
Antigen
Alternative Name FGFR1 (FGFR1 Antibody Abstract)
Background The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1
Molecular Weight 91868 Da
Gene ID 2260
NCBI Accession NP_001167534
Research Area Cancer, Growth Factors, Tyrosine Kinases, Angiogenesis, Cytokines, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGFR1 Antibody Target Details FGFR1 Handling References for anti-FGFR1 Antibody (ABIN951300) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details References for anti-FGFR1 Antibody (ABIN951300) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-FGFR1 Antibody (ABIN951300)

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details Handling Images back to top
Background publications

Turner, Pearson, Sharpe, Lambros, Geyer, Lopez-Garcia, Natrajan, Marchio, Iorns, Mackay, Gillett, Grigoriadis, Tutt, Reis-Filho, Ashworth: "FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2085-94, 2010

Chen, Tian, Liu, Zhou, Schmidt, Henne-Bruns, Bachem, Kornmann: "Inhibition of endogenous SPARC enhances pancreatic cancer cell growth: modulation by FGFR1-III isoform expression." in: British journal of cancer, Vol. 102, Issue 1, pp. 188-95, 2010

Kang, Wong, Shi, Hébert: "The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14571-80, 2009

Marzioni, Lorenzi, Mazzucchelli, Capparuccia, Morroni, Fiorini, Bracalenti, Catalano, David, Castellucci, Muzzonigro, Montironi: "Expression of basic fibroblast growth factor, its receptors and syndecans in bladder cancer." in: International journal of immunopathology and pharmacology, Vol. 22, Issue 3, pp. 627-38, 2009

Images

Product Details anti-FGFR1 Antibody Target Details FGFR1 Application Details Handling References for anti-FGFR1 Antibody (ABIN951300) back to top
Supplier Images
Western Blotting (WB) image for anti-FGFR1 antibody (Fibroblast Growth Factor Receptor 1) (Tyr307) (ABIN951300) Western blot analysis of FGFR1 (arrow) using rabbit polyclonal FGFR1-Y307 . 293...