Browse our anti-FGFR2 (FGFR2) Antibodies

Full name:
anti-Fibroblast Growth Factor Receptor 2 Antibodies (FGFR2)
On www.antibodies-online.com are 303 Fibroblast Growth Factor Receptor 2 (FGFR2) Antibodies from 27 different suppliers available. Additionally we are shipping FGFR2 Proteins (44) and FGFR2 Kits (22) and many more products for this protein. A total of 398 FGFR2 products are currently listed.
Synonyms:
AU043015, AW556123, BBDS, Bek, BFR-1, CD332, CEK3, CFD1, DKFZp469H1521, ECT1, fc56c05, FGF-R, FGFR, Fgfr-2, Fgfr-7, FGFR2, FGFR2IIIb, Fgfr7, fgfr72IIIb, JWS, K-SAM, KGFR, KGFRTr, svs, TK14, TK25, wu:fc56c05, xfgfr2
list all antibodies Gene Name GeneID UniProt
FGFR2 2263 P21802
FGFR2 14183 P21803
FGFR2 25022  

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Most Popular Reactivities for anti-FGFR2 (FGFR2) Antibodies

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anti-Human FGFR2 Antibodies:

anti-Mouse (Murine) FGFR2 Antibodies:

anti-Rat (Rattus) FGFR2 Antibodies:

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Top referenced anti-FGFR2 Antibodies

  1. Human Polyclonal FGFR2 Primary Antibody for FACS, IF - ABIN391965 : Freeman, Gangula, Welm, Ozen, Foster, Rosen, Ittmann, Greenberg, Spencer et al.: Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase ... in Cancer research 2003 (PubMed)
    Show all 9 references for 391965

  2. Human Polyclonal FGFR2 Primary Antibody for EIA, WB - ABIN359856 : Goriely, McVean, Röjmyr, Ingemarsson, Wilkie: Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line. in Science (New York, N.Y.) 2003 (PubMed)
    Show all 5 references for 359856

  3. Human Polyclonal FGFR2 Primary Antibody for EIA, IHC (p) - ABIN359855 : Fomenkov, Huang, Topaloglu, Brechman, Osada, Fomenkova, Yuriditsky, Trink, Sidransky, Ratovitski: P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for 359855

  4. Human Polyclonal FGFR2 Primary Antibody for EIA, IHC (p) - ABIN359854 : Katoh, Katoh: Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26. in International journal of molecular medicine 2003 (PubMed)
    Show all 5 references for 359854

  5. Human Polyclonal FGFR2 Primary Antibody for FACS, IF - ABIN391966 : Katoh, Katoh: FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26. in International journal of oncology 2003 (PubMed)
    Show all 5 references for 391966

  6. Human Polyclonal FGFR2 Primary Antibody for EIA, WB - ABIN359857 : Park, Meyers, Li, Theda, Day, Orlow, Jones, Jabs: Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability. in Human molecular genetics 1996 (PubMed)
    Show all 4 references for 359857

  7. Human Polyclonal FGFR2 Primary Antibody for FACS, IF - ABIN391968 : Rutland, Pulleyn, Reardon, Baraitser, Hayward, Jones, Malcolm, Winter, Oldridge, Slaney: Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes. in Nature genetics 1995 (PubMed)
    Show all 3 references for 391968

  8. Human Polyclonal FGFR2 Primary Antibody for IHC (p), WB - ABIN1106281 : Xu, Weinstein, Li, Naski, Cohen, Ornitz, Leder, Deng: Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. in Development (Cambridge, England) 1998 (PubMed)
    Show all 2 references for 1106281

  9. Human Polyclonal FGFR2 Primary Antibody for ELISA, WB - ABIN334399 : McGrath, Lee, Buring, Hunter, De Vivo: Novel breast cancer risk alleles and endometrial cancer risk. in International journal of cancer 2008 (PubMed)
    Show all 2 references for 334399

More Antibodies against FGFR2 Interaction Partners

Human Fibroblast Growth Factor Receptor 2 (FGFR2) interaction partners

  1. FGFR inhibitors, particularly BGJ398, are therapeutic options for cholangiocarcinoma patients harboring FGFR2-CCDC6 (show CCDC6 Antibodies) fusions.

  2. High FGFR2 expression is associated with Gastric Cancers.

  3. FGF7 (show FGF7 Antibodies) stimulation of cell invasion and migration was partially suppressed by the FGFR2 knockdown. In addition, FGF7 (show FGF7 Antibodies)/FGFR2 upregulated THBS1 (show THBS1 Antibodies), and cell invasion and migration were decreased by knockdown of THBS1 (show THBS1 Antibodies)

  4. Two novel FGFR 2 gene missense mutations in Chinese patients with Crouzon syndrome were identified.

  5. Incidence of progression (progressed, recurred or died from disease) of endometrioid endometrial cancer was significantly more prevalent (32/125, 26%) among patients with FGFR2 mutation versus wild type (120/848, 14%; p<0.001, Chi-square test).

  6. We show that the decrease in PI(4,5)P2 level under non-stimulated conditions inhibits PTEN (show PTEN Antibodies) activity leading to the aberrant activation of the oncoprotein Akt (show AKT1 Antibodies). As well as defining a novel mechanism of Akt (show AKT1 Antibodies) phosphorylation with important therapeutic consequences, we also demonstrate that differential expression levels of FGFR2, Plc11 and Grb2 (show GRB2 Antibodies) correlate with patient survival

  7. High FGFR2 expression was significantly associated with the depth of invasion, lymph-node metastasis, pathological stage, and distant metastasis or recurrent disease in gastric cancer.

  8. fibroblast growth factor receptor 2 overexpression is correlated with decreased survival in most solid tumors, suggesting that the expression status of fibroblast growth factor receptor 2 is a valuable prognostic biomarker and a novel therapeutic target in human solid tumors.

  9. The results indicate that suramin blocks the interaction between hFGF1 and FGFR2 D2.

  10. We thus propose a molecular mechanism by which FGFR2 can confer increased breast cancer risk that is consistent with oestrogen exposure as a major driver of breast cancer risk. Our findings may have implications for the clinical use of FGFR2 inhibitors.

Mouse (Murine) Fibroblast Growth Factor Receptor 2 (FGFR2) interaction partners

  1. Fgfr2 is seen within submucosal glandular epithelial cells. The medial nasal glands were missing in Fgfr2b mutants.

  2. It is well accepted that myelin is a biologically active membrane in active communication with the axons. However, the axonal signals, the receptors on myelin, and the integration of intracellular signaling pathways emanating downstream from these receptors that drive the growth of the myelin sheath remain poorly understood in the CNS. This study brings up the intriguing possibility that FGF receptor 2, in the oligodendr

  3. data suggest that FGF2 (show FGF2 Antibodies) levels are critically related to anxiety behavior and hypothalamic pituitary- adrenal axis activity, likely through modulation of hippocampal glucocorticoid receptor (show NR3C1 Antibodies) expression, an effect that is likely receptor mediated, albeit not by FGFR1 (show FGFR1 Antibodies), FGFR2, and FGFR3 (show FGFR3 Antibodies).

  4. Results show that Fgfr2 regulates both the formation and resolution of tetrads and rosettes in the mouse embryo, possibly in part by spatially restricting atypical protein kinase C (show PRKCZ Antibodies), a negative regulator of non-muscle myosin IIB (show MYH10 Antibodies).

  5. FGFR2c signaling regulates branching morphogenesis through the activation of FGFR2b signaling via increased FGF10 (show FGF10 Antibodies) autocrine. These results provide new insight into the mechanisms by which crosstalk between FGFR2b and FGFR2c results in efficient branching morphogenesis.

  6. Fgfr2 is critical for bladder mesenchyme patterning by virtue of its role in modulation of hedgehog (show SHH Antibodies) signaling

  7. Ectopic expression of Fgfr2c was detected within the affected sutures of Bcl11b (show BCL11B Antibodies)(-/-) mice. Ectopic expression of Fgfr2c in the sutural mesenchyme, without concomitant changes in the expression of FGF ligands, appears to induce the RUNX2 (show RUNX2 Antibodies)-dependent osteogenic program and craniosynostosis in Bcl11b (show BCL11B Antibodies)(-/-) mice.

  8. Calvarial osteoblasts from Fgfr2c gain-of-function mice had enhanced osteoblastic function and maturation with concomitant increase in ERK-MAPK (show MAPK1 Antibodies) activation. In vitro inhibition with U0126 mitigated ERK (show EPHB2 Antibodies) protein activation levels and reduced alkaline phosphatase activity. FGFR2c-mediated ERK-MAPK (show MAPK1 Antibodies) signaling is a key mediator of craniofacial growth and coronal suture development.

  9. Fgfr1 (show FGFR1 Antibodies) and Fgfr2 in the palatal and mandibular mesenchyme have roles in regulating shelf medial wall protrusion and growth of the mandible to coordinate the craniofacial tissue movements that are required for palatal shelf elevation

  10. Data demonstrate an essential role for FGFR1 (show FGFR1 Antibodies) and FGFR2 in endothelial cells for cardiac functional recovery and vascular remodeling following in vivo cardiac ischemia-reperfusion injury, without affecting the cardiac hypertrophic response.

Pig (Porcine) Fibroblast Growth Factor Receptor 2 (FGFR2) interaction partners

  1. mRNA and protein expression of FGFR-1 (show FGFR1 Antibodies), FGFR-2 in the porcine umbilical cord during pregnancy.

  2. EGFR (show EGFR Antibodies), VEGFR (show KDR Antibodies) and FGFR are expressed in porcine oviduct and endometrium during the time of implantation [review]

  3. analysis of regulation of endometrial fibroblast growth factor 7 (FGF-7 (show FGF7 Antibodies)) and its receptor FGFR2IIIb

Cow (Bovine) Fibroblast Growth Factor Receptor 2 (FGFR2) interaction partners

  1. FGF10 (show FGF10 Antibodies) and its receptor FGFR2b are more expressed in subordinate follicles; FGF10 (show FGF10 Antibodies) acts as an important regulator of follicular growth in cattle.

  2. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF (show FGF2 Antibodies) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

  3. These data support a role for FGF10 (show FGF10 Antibodies) and fibroblast growth factor receptor 2B in signaling to granulosa cells from theca cells and/or the oocyte.(fibroblast growth factor receptor 2B)

  4. FGF10 (show FGF10 Antibodies) mRNA expression did not change during functional luteolysis, whereas FGFR2B mRNA abundance decreased significantly at 2, 4, and 12 hr after PGF2alpha, and returned to pretreatment levels for the period 24-64 hr post-PGF2alpha

Zebrafish Fibroblast Growth Factor Receptor 2 (FGFR2) interaction partners

  1. we show that minimal amounts of Fgfr1a or Fgfr2 are required to initiate a regulatory cascade in pharyngeal endoderm reducing expression of fsta, thereby allowing correct BMP signaling to the maturing chondrocytes of the head cartilage.

  2. the roles of Fgfr2 signaling in zebrafish left-right asymmetry

FGFR2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Alternative names and synonyms associated with FGFR2

  • fibroblast growth factor receptor 2 (FGFR2) antibody
  • fibroblast growth factor receptor 2 (fgfr2) antibody
  • fibroblast growth factor receptor 2 (Fgfr2) antibody
  • AU043015 antibody
  • AW556123 antibody
  • BBDS antibody
  • Bek antibody
  • BFR-1 antibody
  • CD332 antibody
  • CEK3 antibody
  • CFD1 antibody
  • DKFZp469H1521 antibody
  • ECT1 antibody
  • fc56c05 antibody
  • FGF-R antibody
  • FGFR antibody
  • Fgfr-2 antibody
  • Fgfr-7 antibody
  • FGFR2 antibody
  • FGFR2IIIb antibody
  • Fgfr7 antibody
  • fgfr72IIIb antibody
  • JWS antibody
  • K-SAM antibody
  • KGFR antibody
  • KGFRTr antibody
  • svs antibody
  • TK14 antibody
  • TK25 antibody
  • wu:fc56c05 antibody
  • xfgfr2 antibody

Protein level used designations for FGFR2

fibroblast growth factor receptor 2 , bacteria-expressed kinase , keratinocyte growth factor receptor , fibroblast growth factor receptor 2 IIIb , fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) , BEK fibroblast growth factor receptor , FGF receptor , FGFR-2 , hydroxyaryl-protein kinase , protein tyrosine kinase, receptor like 14 , soluble FGFR4 variant 4 , FGF-7 receptor 2IIIb , fgf receptor , chicken tyrosine kinase (cek3) , receptor tyrosine kinase , tyrosine kinase receptor CEK3 , fibroblast growth factor receptor-2

GENE ID SPECIES
443548 Ovis aries
466220 Pan troglodytes
715949 Macaca mulatta
100033956 Equus caballus
100084641 Ornithorhynchus anatinus
100124910 Xenopus (Silurana) tropicalis
100171540 Pongo abelii
100468267 Ailuropoda melanoleuca
2263 Homo sapiens
14183 Mus musculus
25022 Rattus norvegicus
415125 Canis lupus familiaris
396762 Sus scrofa
404193 Bos taurus
396259 Gallus gallus
399325 Xenopus laevis
100009417 Oryctolagus cuniculus
100379152 Cavia porcellus
352940 Danio rerio
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