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anti-Monkey FGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR2 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 2 (FGFR2) Antibodies
  • AU043015
  • AW556123
  • BBDS
  • bek
  • Bek
  • BEK
  • bfr-1
  • BFR-1
  • cd332
  • CD332
  • CEK3
  • cek3
  • CFD1
  • cfd1
  • DKFZp469H1521
  • ect1
  • ECT1
  • fc56c05
  • FGF-R
  • FGFR
  • fgfr-2
  • Fgfr-2
  • Fgfr-7
  • FGFR2
  • FGFR2IIIb
  • Fgfr7
  • fgfr72IIIb
  • jws
  • JWS
  • K-SAM
  • k-sam
  • KGFR
  • kgfr
  • KGFRTr
  • svs
  • tk14
  • TK14
  • tk25
  • TK25
  • wu:fc56c05
  • xfgfr2
Epitope
AA 7-37, N-Term
40
33
23
21
14
8
7
7
6
5
5
5
5
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
270
56
46
2
2
2
2
2
2
1
1
1
1
Host
Rabbit
195
66
13
2
Clonality
Polyclonal
Conjugate
This FGFR2 antibody is un-conjugated
12
11
10
10
9
9
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
191
122
90
80
53
46
18
11
8
8
1
1
1
Supplier
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Catalog No. ABIN391965
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN2439769 FACS IF IHC (p) WB Rabbit Ig Fraction N-Term Log in to see Polyclonal

Top referenced anti-FGFR2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

  • Human Polyclonal FGFR2 Primary Antibody for FACS, IF - ABIN391965 (9 Publications): Freeman, Gangula, Welm, Ozen, Foster, Rosen, Ittmann, Greenberg, Spencer et al.: Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase ... in Cancer research 2003 (PubMed)

Similar anti-FGFR2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Monkey
ELISA 13 Antibodies 18 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 3 Antibodies 3 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 1 Antibodies
Immunofluorescence (IF) 6 Antibodies 6 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 13 Antibodies 19 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies 14 Antibodies
Immunoprecipitation (IP) 2 Antibodies 2 Antibodies
Western Blotting (WB) 27 Antibodies 36 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 2 (FGFR2) Antibodies
Epitope AA 7-37, N-Term
(40), (33), (23), (21), (14), (8), (7), (7), (6), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Monkey, Mouse (Murine), Rat (Rattus)
(270), (56), (46), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(195), (66), (13), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This FGFR2 antibody is un-conjugated
(12), (11), (10), (10), (9), (9), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(191), (122), (90), (80), (53), (46), (18), (11), (8), (8), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-FGFR2 Antibody

Target Details FGFR2 Application Details Handling References for anti-FGFR2 Antibody (ABIN391965) Images
Specificity This FGFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~44 amino acids from the N-terminal region of human FGFR2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This FGFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 AA from the N-terminal region of human FGFR2.
Clone RB01567
Isotype Ig

Target Details FGFR2

Product Details anti-FGFR2 Antibody Application Details Handling References for anti-FGFR2 Antibody (ABIN391965) Images back to top
Antigen
Alternative Name FGFR2 (FGFR2 Antibody Abstract)
Background FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in the gene are associated with many craniosynostotic syndromes and bone malformations. The genomic organization of the gene encompasses 20 exons. Alternative splicing in multiple exons, including those encoding the Ig-like domains, the transmembrane region and the carboxyl terminus, results in varied isoforms which differ in structure and specificity. Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF.
Synonyms: fibroblast growth factor receptor 2
Molecular Weight 92025 DA
Gene ID 2263
UniProt P21802
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGFR2 Antibody Target Details FGFR2 Handling References for anti-FGFR2 Antibody (ABIN391965) Images back to top
Application Notes WB = 1:1000, IF = 1:50-100, FACS = 1:10-50, IHC (p) = 1:50-100
Restrictions For Research Use only

Handling

Product Details anti-FGFR2 Antibody Target Details FGFR2 Application Details References for anti-FGFR2 Antibody (ABIN391965) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-FGFR2 Antibody (ABIN391965)

Product Details anti-FGFR2 Antibody Target Details FGFR2 Application Details Handling Images back to top
Product cited in:

Guan, Gao, Zhou, Wang, Zheng, Guo, Chang, Li, Wang: "miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 5, pp. 1589-600, 2015

Matsui-Inohara, Uematsu, Narita, Satoh, Yonezawa, Kuroda, Ito, Yoneda, Kawarai, Sugiya, Watanabe, Senpuku: "E2F-1-deficient NOD/SCID mice developed showing decreased saliva production." in: Experimental biology and medicine (Maywood, N.J.), Vol. 234, Issue 12, pp. 1525-36, 2009

Page, Ambady, Holmes, Vilner, Kole, Kashpur, Huntress, Vojtic, Whitton, Dominko: "Induction of stem cell gene expression in adult human fibroblasts without transgenes." in: Cloning and stem cells, Vol. 11, Issue 3, pp. 417-26, 2009

Mondrinos, Koutzaki, Lelkes, Finck: "A tissue-engineered model of fetal distal lung tissue." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 293, Issue 3, pp. L639-50, 2007

Background publications

Freeman, Gangula, Welm, Ozen, Foster, Rosen, Ittmann, Greenberg, Spencer et al.: "Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase ..." in: Cancer research, Vol. 63, Issue 19, pp. 6237-43, 2003

Goriely, McVean, Röjmyr, Ingemarsson, Wilkie: "Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line." in: Science (New York, N.Y.), Vol. 301, Issue 5633, pp. 643-6, 2003

Fomenkov, Huang, Topaloglu, Brechman, Osada, Fomenkova, Yuriditsky, Trink, Sidransky, Ratovitski: "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23906-14, 2003

Katoh, Katoh: "Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26." in: International journal of molecular medicine, Vol. 11, Issue 5, pp. 579-83, 2003

Katoh, Katoh: "FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26." in: International journal of oncology, Vol. 22, Issue 5, pp. 1155-9, 2003

Images

Product Details anti-FGFR2 Antibody Target Details FGFR2 Application Details Handling References for anti-FGFR2 Antibody (ABIN391965) back to top
Supplier Images
Western Blotting (WB) image for anti-FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (AA 7-37) (ABIN391965) Western blot analysis of anti-hFGFR2-R22 Pab (ABIN391965) in 293 cell line lysates tr...
Immunohistochemistry (IHC) image for anti-FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (AA 7-37) (ABIN391965) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
 image for anti-FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (AA 7-37) (ABIN391965) C:FGFR2/isolectinB4 (C) and FGFR1/isolectinB4 (D) staining of apparent mesenchymal ce...