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Browse our anti-FGFR3 (FGFR3) Antibodies

Full name:
anti-Fibroblast Growth Factor Receptor 3 Antibodies (FGFR3)
On are 130 Fibroblast Growth Factor Receptor 3 (FGFR3) Antibodies from 26 different suppliers available. Additionally we are shipping FGFR3 Proteins (44) and FGFR3 Kits (19) and many more products for this protein. A total of 209 FGFR3 products are currently listed.
ACH, CD333, CEK2, fc27h01, Fgfr-3, FGFR3, Flg-2, FR3, HBGFR, HSFGFR3EX, JTK4, LOC100034114, Mfr3, sam3, wu:fc27h01
list all antibodies Gene Name GeneID UniProt
FGFR3 2261 P22607
FGFR3 14184  
FGFR3 84489  

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Most Popular Reactivities for anti-FGFR3 (FGFR3) Antibodies

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anti-Human FGFR3 Antibodies:

anti-Mouse (Murine) FGFR3 Antibodies:

anti-Rat (Rattus) FGFR3 Antibodies:

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Top referenced anti-FGFR3 Antibodies

  1. Human Polyclonal FGFR3 Primary Antibody for EIA, IHC (p) - ABIN359858 : Sturla, Merrick, Burchill: FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells. in British journal of cancer 2003 (PubMed)
    Show all 5 references for ABIN359858

  2. Human Polyclonal FGFR3 Primary Antibody for IHC (p), WB - ABIN391969 : Lievens, Liboi et al.: The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) ... in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for ABIN391969

  3. Human Polyclonal FGFR3 Primary Antibody for IHC, ELISA - ABIN1533273 : Shimizu, Ishikawa, Iwai, Ueki, Sugihara, Onishi, Kuninaka, Miyamoto, Toyama, Ijiri, Mori, Matsuzaki, Yaguchi, Nishio, Kawakami, Ikeda, Saya: Fibroblast growth factor-2 (Fgf2) is an important factor that maintains cellular immaturity and contributes to aggressiveness of osteosarcoma. in Molecular cancer research : MCR 2012 (PubMed)

More Antibodies against FGFR3 Interaction Partners

Human Fibroblast Growth Factor Receptor 3 (FGFR3) interaction partners

  1. FGFR3 biology and skeletal disease

  2. analysis of FGFR3 and FGFR4 (show FGFR4 Antibodies) gene polymorphisms in breast cancer in Chinese women of Heilongjiang province reveals that SNPs rs1966265 and rs351855 in FGFR4 (show FGFR4 Antibodies) , but not rs2234909 and rs3135848 in FGFR3 are associated with breast cancer

  3. The FGFR3, PIK3CA (show PIK3CA Antibodies), TERT (show TERT Antibodies) mutations, along with aberrant DNA methylation (show HELLS Antibodies) patterns, can serve as reliable genetic markers for the diagnosis of urinary bladder cancer. (Review)

  4. The most notable effect of the achondroplasia mutation is increased propensity for FGFR3 dimerization in the absence of ligand.

  5. Findings provide new evidence that PRMT5 (show PRMT5 Antibodies) plays an important role in CRC (show CALR Antibodies) pathogenesis through epigenetically regulating arginine methylation of oncogenes such as eIF4E (show EIF4E Antibodies) and FGFR3.

  6. Expression of FGF-2 (show FGF2 Antibodies), FGFR-2 (show FGFR2 Antibodies) and FGFR-3 was upregulated in patients with potentially malignant oral lesions serving as biomarkers of malignant transformation to oral squamous cell carcinoma.

  7. FGF receptor (FGFR) 3 may serve as a promising biomarker for Bladder Cancer. Mutations of this gene are prevalent in BC.

  8. miR (show MLXIP Antibodies)-100 may activate MMP13 (show MMP13 Antibodies) through 3'UTR (show UTS2R Antibodies)-suppressoin of FGFR3 mRNA to facilitate development of lumbar disc degeneration.

  9. Among patients with an FGFR3 mutation in the initial tumor, a noninvasive urine test during follow-up can be valuable in diagnosing or predicting subsequent recurrence.

  10. TP53 (show TP53 Antibodies) and FGFR3 mutations in bladder tumors increased and decreased respectively with increasing tumor stage and cellular grade.

Mouse (Murine) Fibroblast Growth Factor Receptor 3 (FGFR3) interaction partners

  1. loss of Fgfr3 function leads to the formation of chondroma-like lesions via downregulation of MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) signaling and upregulation of IHH (show IHH Antibodies).

  2. A proliferation-independent and SOX9 (show SOX9 Antibodies)-dependent differentiation block is a key driving mechanism responsible for poor endochondral bone growth in achondroplasia disorders caused by mutations in FGFR3.

  3. This study showed constitutively active form of Fgfr3 to increase FGF signaling.

  4. FGFR3 induces degradation of Bmpr1a (show BMPR1A Antibodies) to regulate skeletal development.

  5. microtubule formation is a major downstream effector of Fgf-receptor 3 and this pathway impacts the formation of fluid spaces in the organ of Corti.

  6. FGFR3 plays a pivotal role in the specific uptake of BoNT/A across the cell membrane being part of a larger receptor complex involving ganglioside- and protein-protein interactions.

  7. FGFR3 overexpression in lung leads to adenocarcinoma.

  8. our results demonstrate that FGFR1 (show FGFR1 Antibodies) is crucial for S115 breast cancer cell proliferation and tumor growth and angiogenesis, whereas FGFR2 (show FGFR2 Antibodies) and FGFR3 are less critical for the growth of these cells

  9. Peptide P3 inhibited tyrosine kinase (show TYRO3 Antibodies) activity of FGFR3 and the ERK/MAPK (show MAPK1 Antibodies) pathway.

  10. dysregulation of Sox9 (show SOX9 Antibodies) and beta-catenin (show CTNNB1 Antibodies) levels and activity in growth plate chondrocytes is an important underlying mechanism in skeletal diseases caused by mutations in FGFR3

Zebrafish Fibroblast Growth Factor Receptor 3 (FGFR3) interaction partners

Cow (Bovine) Fibroblast Growth Factor Receptor 3 (FGFR3) interaction partners

  1. The ectodomain of FGFR3 is proteolytically cleaved in response to ligand-induced receptor activation by FGF1, but unlike most regulated intramembrane proteolysis target proteins, it requires endocytosis and does not involve a metalloproteinase.

  2. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF (show FGF2 Antibodies) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

  3. chondrodysplastic dwarfism in Japanese brown cattle is not caused by mutation in the FGFR3 gene

FGFR3 Antigen Profile

Antigen Summary

This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Alternative names and synonyms associated with FGFR3

  • fibroblast growth factor receptor 3 (FGFR3) antibody
  • fibroblast growth factor receptor 3 (LOC100034114) antibody
  • FGF receptor 3 (fgfr3) antibody
  • fibroblast growth factor receptor 3 (Fgfr3) antibody
  • fibroblast growth factor receptor 3 (fgfr3) antibody
  • ACH antibody
  • CD333 antibody
  • CEK2 antibody
  • fc27h01 antibody
  • Fgfr-3 antibody
  • FGFR3 antibody
  • Flg-2 antibody
  • FR3 antibody
  • HBGFR antibody
  • HSFGFR3EX antibody
  • JTK4 antibody
  • LOC100034114 antibody
  • Mfr3 antibody
  • sam3 antibody
  • wu:fc27h01 antibody

Protein level used designations for FGFR3

fibroblast growth factor receptor 3 , FGFR-3 , fibroblast growth factor receptor 3 variant 4 , hydroxyaryl-protein kinase , tyrosine kinase JTK4 , heparin-binding growth factor receptor , fibroblast growth factor receptor 3-IIIc , tyrosine kinase (cek2) , tyrosine kinase receptor CEK2 , fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)

461067 Pan troglodytes
554324 Ovis aries
712829 Macaca mulatta
100034114 Equus caballus
100141386 Felis catus
399347 Xenopus laevis
2261 Homo sapiens
14184 Mus musculus
84489 Rattus norvegicus
396515 Gallus gallus
100732948 Cavia porcellus
58129 Danio rerio
488808 Canis lupus familiaris
281769 Bos taurus
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