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|Antigen||Fibroblast Growth Factor Receptor 3 (FGFR3) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This FGFR3 antibody is conjugated to Alexa Fluor 350 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-FGFR3 AntibodyTarget Details FGFR3 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic phosphopeptide derived from human FGFR3 around the phosphorylation site of Tyr724|
Target Details FGFR3Product Details anti-FGFR3 Antibody Application Details Handling Images back to top
|Alternative Name||Fgfr3 (FGFR3 Antibody Abstract)|
The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
Synonyms: FGFR3 phospho Y724, FGFR3 phospho Tyr724, p-FGFR3 phospho Y724, ACH, CD 333, CD333, CD333 antigen, CEK 2, CEK2, FGFR 3, Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism, Fibroblast growth factor receptor 3, Heparin binding growth factor receptor, HSFGFR3EX, Hydroxyaryl protein kinase, JTK 4, JTK4, MFR 3, SAM 3, Tyrosine kinase JTK 4, Tyrosine kinase JTK4, Z FGFR 3.
|Research Area||Stem Cells, Growth Factors, Angiogenesis|
|Pathways||RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding|
Application DetailsProduct Details anti-FGFR3 Antibody Target Details FGFR3 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-FGFR3 Antibody Target Details FGFR3 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|