anti-Human FGFR3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR3 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 3 (FGFR3) Antibodies
  • FGFR3
  • LOC100034114
  • ACH
  • CD333
  • CEK2
  • HSFGFR3EX
  • JTK4
  • FR3
  • Fgfr-3
  • Flg-2
  • HBGFR
  • Mfr3
  • sam3
  • fc27h01
  • wu:fc27h01
  • fibroblast growth factor receptor 3
  • FGF receptor 3
  • FGFR3
  • LOC100034114
  • fgfr3
  • Fgfr3
Epitope
C-Term
17
15
14
12
12
11
10
8
6
5
5
4
4
4
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
199
52
37
6
4
3
3
1
1
1
1
1
Host
Rabbit
137
69
1
Clonality
Polyclonal
Conjugate
This FGFR3 antibody is un-conjugated
13
13
10
7
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
134
102
99
57
44
13
13
10
5
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN359858
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.4040785 ABIN407668 IHC (p) IHC WB Rabbit Log in to see Polyclonal 1
13.4040785 ABIN1895789 IHC (p) Rabbit IgG AA 359-372 Log in to see Polyclonal
13.4040785 ABIN4311562 CyTOF ELISA FACS IHC IHC (p) WB Mouse IgG1 Log in to see 2H10B4
1 ABIN391969 IHC (p) WB Rabbit Ig AA 776-806, C-Term Log in to see Polyclonal 2
1 ABIN265418 IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN3043988 ICC IHC (p) WB Rabbit IgG AA 110-129, N-Term Log in to see Polyclonal
1 ABIN372898 IHC (p) Rabbit IgG AA 359-372 Log in to see Polyclonal
1 ABIN1688131 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1688130 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN269673 IHC (p) IHC WB Rabbit N-Term Log in to see Polyclonal 1
1 ABIN957951 ICC IHC (p) WB Mouse IgG1 Log in to see 136312
1 ABIN1712098 IHC (p) WB HRP Rabbit IgG pTyr724 Log in to see Polyclonal
1 ABIN2450560 IHC (p) WB Mouse IgG1 AA 23-375 Log in to see 1B10
1 ABIN4311553 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN329852 IHC (p) IP WB Rabbit IgG AA 359-372, C-Term Log in to see Polyclonal
1 ABIN329853 IHC (p) IP WB Rabbit IgG AA 792-806, N-Term Log in to see Polyclonal
1 ABIN1701081 IHC (p) WB Biotin Rabbit IgG pTyr724 Log in to see Polyclonal
1 ABIN1714583 IF (p) IHC (p) WB Rabbit IgG pTyr724 Log in to see Polyclonal
1 ABIN658761 IHC (p) WB Rabbit Ig AA 468-495, Center Log in to see Polyclonal
1 ABIN2620873 ICC IHC (p) WB Rabbit IgG AA 110-129 Log in to see Polyclonal

Top referenced anti-FGFR3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-FGFR3 Antibodies

Application / Reactivity Human
Cytometry by Time of Flight (CyTOF) 2 Antibodies
ELISA 98 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 57 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 10 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 98 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 44 Antibodies
Immunoprecipitation (IP) 13 Antibodies
Western Blotting (WB) 133 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 3 (FGFR3) Antibodies
Epitope C-Term
(17), (15), (14), (12), (12), (11), (10), (8), (6), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human
(199), (52), (37), (6), (4), (3), (3), (1), (1), (1), (1), (1)
Host Rabbit
(137), (69), (1)
Clonality
Polyclonal
Conjugate This FGFR3 antibody is un-conjugated
(13), (13), (10), (7), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(134), (102), (99), (57), (44), (13), (13), (10), (5), (2), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-FGFR3 Antibody

Target Details FGFR3 Application Details Handling ProductDetails: References for anti-FGFR3 antibody (ABIN359858) Images
Specificity This antibody reacts to FGFR3.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGFR3.
Isotype Ig

Target Details FGFR3

Product Details anti-FGFR3 Antibody Application Details Handling ProductDetails: References for anti-FGFR3 antibody (ABIN359858) Images back to top
Antigen
Alternative Name CD333 / FGFR3 (FGFR3 Antibody Abstract)
Background FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.Synonyms: FGFR-3, Fibroblast growth factor receptor 3, JTK4
Gene ID 2261, 9606
UniProt P22607
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding

Application Details

Product Details anti-FGFR3 Antibody Target Details FGFR3 Handling ProductDetails: References for anti-FGFR3 antibody (ABIN359858) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FGFR3 Antibody Target Details FGFR3 Application Details ProductDetails: References for anti-FGFR3 antibody (ABIN359858) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-FGFR3 antibody (ABIN359858)

Product Details anti-FGFR3 Antibody Target Details FGFR3 Application Details Handling Images back to top
Background publications

Sturla, Merrick, Burchill: "FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells." in: British journal of cancer, Vol. 89, Issue 7, pp. 1276-84, 2003

Lievens, Liboi et al.: "The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) ..." in: The Journal of biological chemistry, Vol. 278, Issue 19, pp. 17344-9, 2003

Reinhart, Eulert, Bill, Würzler, Phan The, Reuther: "[Typical features of craniofacial growth of the FGFR3-associated coronal synostosis syndrome (so-called Muenke craniosynostosis)]." in: Mund-, Kiefer- und Gesichtschirurgie : MKG, Vol. 7, Issue 3, pp. 132-7, 2003

Pehlivan, Ozkinay, Okutman, Coğulu, Ozcan, Cankaya, Ulgenalp: "Achondroplasia in Turkey is defined by recurrent G380R mutation of the FGFR3 gene." in: The Turkish journal of pediatrics, Vol. 45, Issue 2, pp. 99-101, 2003

Santra, Zhan, Tian, Barlogie, Shaughnessy: "A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript." in: Blood, Vol. 101, Issue 6, pp. 2374-6, 2003

Images

Product Details anti-FGFR3 Antibody Target Details FGFR3 Application Details Handling ProductDetails: References for anti-FGFR3 antibody (ABIN359858) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FGFR3 antibody (Fibroblast Growth Factor Receptor 3) (C-Term) (ABIN359858) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-FGFR3 antibody (Fibroblast Growth Factor Receptor 3) (C-Term) (ABIN359858) Western blot analysis of anti-FGFR3 Pab in Jurkat cell lysate. FGFR3 (Arrow) was dete...