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anti-Human FGFR4 antibody for Immunocytochemistry

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • cd334
  • CD334
  • etID309818.21
  • Fgfr-4
  • fgfr-4
  • fgfr-4c
  • fgfr4
  • FGFR4
  • JTK2
  • jtk2
  • tkf
  • TKF
  • wu:fc13h10
  • XFGFR-4
  • XFGFR-4a
  • xfgfr4
  • zgc:111935
Reactivity
Human
169
43
35
2
2
1
Host
Mouse
106
66
7
1
Clonality
Monoclonal
Conjugate
This FGFR4 antibody is un-conjugated
7
6
6
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
139
83
44
31
27
22
11
7
5
5
5
1
1
Supplier
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Catalog No. ABIN969140
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.6663565 ABIN1843605 ICC IF ELISA WB Mouse IgG1 Log in to see
0.0009962841 ABIN1858881 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 168-369 Log in to see Polyclonal
0.0009962841 ABIN4311563 ELISA ICC IF WB Mouse IgG1 Log in to see 7H1
0.0009962841 ABIN4311567 ICC IF IHC IHC (p) Rabbit IgG Log in to see Polyclonal
0.0009962841 ABIN4311568 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-FGFR4 antibody for Immunocytochemistry

Similar anti-FGFR4 Antibodies

Application / Reactivity Human
ELISA 80 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 27 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 22 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 42 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 136 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Reactivity Human
(169), (43), (35), (2), (2), (1)
Host Mouse
(106), (66), (7), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FGFR4 antibody is un-conjugated
(7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(139), (83), (44), (31), (27), (22), (11), (7), (5), (5), (5), (1), (1)
Pubmed 2 references available
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Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling References for anti-FGFR4 Antibody (ABIN969140) Images
Purification Ascites
Immunogen Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.
Clone 7H1
Isotype IgG1

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling References for anti-FGFR4 Antibody (ABIN969140) Images back to top
Antigen
Alternative Name FGFR4 (FGFR4 Antibody Abstract)
Background FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
Molecular Weight 87.9 kDa
Gene ID 2264
HGNC 2264
Research Area Cancer, Growth Factors, Angiogenesis, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling References for anti-FGFR4 Antibody (ABIN969140) Images back to top
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details References for anti-FGFR4 Antibody (ABIN969140) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.

References for anti-FGFR4 Antibody (ABIN969140)

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling Images back to top
Product cited in:

Huang, Yang, Luo, Jin, Wang, McKeehan: "FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver." in: Diabetes, Vol. 56, Issue 10, pp. 2501-10, 2007

Streit, Mestel, Schmidt, Ullrich, Berking: "FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients." in: British journal of cancer, Vol. 94, Issue 12, pp. 1879-86, 2006

Images

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling References for anti-FGFR4 Antibody (ABIN969140) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (ABIN969140) Figure 1: Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfec...
Western Blotting (WB) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (ABIN969140) Figure 2: Western blot analysis using FGFR4 mouse mAb against extracellular domain of...