You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human FGFR4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • cd334
  • CD334
  • etID309818.21
  • Fgfr-4
  • fgfr-4
  • fgfr-4c
  • fgfr4
  • FGFR4
  • JTK2
  • jtk2
  • tkf
  • TKF
  • wu:fc13h10
  • XFGFR-4
  • XFGFR-4a
  • xfgfr4
  • zgc:111935
Epitope
N-Term
22
14
10
7
7
7
6
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
169
43
35
2
2
1
Host
Rabbit
105
67
7
1
Clonality
Polyclonal
Conjugate
This FGFR4 antibody is un-conjugated
7
6
6
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
139
84
44
30
27
22
11
6
6
5
5
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN359859
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34288716 ABIN462135 IHC (fro) IHC (p) ELISA WB Mouse IgG1 Log in to see 4H2B10B2
0.34288716 ABIN3042391 IHC (p) WB Rabbit IgG AA 22-206 Log in to see Polyclonal
0.34288716 ABIN1960119 IHC (p) ELISA WB Mouse IgG1, kappa Log in to see 53CT32-19-3
0.0008982679 ABIN391970 FACS IF IHC (p) WB Rabbit Ig AA 24-55, N-Term Log in to see Polyclonal 1
0.0008982679 ABIN356413 EIA IHC (p) WB Mouse IgG1 Log in to see 53CT32-19-3
0.0008982679 ABIN2856017 IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
0.0008982679 ABIN356412 EIA IHC (p) WB Mouse IgG1 Log in to see 53CT32-19-3
0.0008982679 ABIN1106282 IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2 2
0.0008982679 ABIN671766 IF (p) IHC (p) WB Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008982679 ABIN1502477 IHC (p) WB Mouse kappa, IgG1 Log in to see 53CT32-19-3
0.0008982679 ABIN614490 EIA IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2
0.0008982679 ABIN1997069 IHC (p) ELISA Rabbit IgG AA 1-369 Log in to see Polyclonal
0.0008982679 ABIN2620881 IHC (p) WB Rabbit IgG AA 22-206 Log in to see Polyclonal
0.0008982679 ABIN2851987 IHC (p) ELISA WB Mouse IgG1 kappa Log in to see 53CT32-19-3
0.0008982679 ABIN1858881 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 168-369 Log in to see Polyclonal
0.0008982679 ABIN671768 IHC (p) WB Biotin Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008982679 ABIN671775 IHC (p) WB HRP Rabbit IgG AA 40-90 Log in to see Polyclonal
0.0008982679 ABIN1840505 FACS IF IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.0008982679 ABIN4311564 ELISA IHC (fro) IHC (p) WB Mouse IgG1 Log in to see 4H2B10B2
0.0008982679 ABIN4311565 IHC (p) WB Mouse IgG1 kappa Log in to see 53CT32-19-3

Top referenced anti-FGFR4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-FGFR4 Antibodies

Application / Reactivity Human
ELISA 80 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 27 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 22 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 42 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 136 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Epitope N-Term
(22), (14), (10), (7), (7), (7), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(169), (43), (35), (2), (2), (1)
Host Rabbit
(105), (67), (7), (1)
Clonality
Polyclonal
Conjugate This FGFR4 antibody is un-conjugated
(7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(139), (84), (44), (30), (27), (22), (11), (6), (6), (5), (5), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling References for anti-FGFR4 Antibody (ABIN359859) Images
Specificity This antibody reacts to FGFR4.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FGFR4.
Isotype Ig

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling References for anti-FGFR4 Antibody (ABIN359859) Images back to top
Antigen
Alternative Name CD334 / FGFR4 (FGFR4 Antibody Abstract)
Background FGFR4 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of the gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.Synonyms: FGFR-4, Fibroblast growth factor receptor 4, JTK2, TKF
Gene ID 2264, 9606
UniProt P22455
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling References for anti-FGFR4 Antibody (ABIN359859) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details References for anti-FGFR4 Antibody (ABIN359859) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-FGFR4 Antibody (ABIN359859)

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling Images back to top
Background publications

Jézéquel, Campion, Joalland, Millour, Dravet, Classe, Delecroix, Deporte, Fumoleau, Ricolleau: "G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis." in: British journal of cancer, Vol. 90, Issue 1, pp. 189-93, 2004

Qian, Sano, Asa, Yamada, Horiguchi, Tashiro, Li, Hirokawa, Kovacs, Ezzat: "Cytoplasmic expression of fibroblast growth factor receptor-4 in human pituitary adenomas: relation to tumor type, size, proliferation, and invasiveness." in: The Journal of clinical endocrinology and metabolism, Vol. 89, Issue 4, pp. 1904-11, 2004

Yu, Asa, Weigel, Ezzat: "Pituitary tumor AP-2alpha recognizes a cryptic promoter in intron 4 of fibroblast growth factor receptor 4." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 19597-602, 2003

Becker, Nieters, Chang-Claude: "The fibroblast growth factor receptor gene Arg388 allele is not associated with early lymph node metastasis of breast cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 12, Issue 6, pp. 582-3, 2003

Takenaka, Yasuno, Kishimoto: "Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin." in: Archives of dermatological research, Vol. 294, Issue 7, pp. 331-8, 2002

Images

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling References for anti-FGFR4 Antibody (ABIN359859) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (N-Term) (ABIN359859) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-FGFR4 antibody (Fibroblast Growth Factor Receptor 4) (N-Term) (ABIN359859) Western blot analysis of anti-FGFR4 Pab in THP-1 cell lysate. FGRFR4 (Arrow) was dete...