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anti-Mouse (Murine) FGFR4 antibody for ELISA

Recommended FGFR4 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Epitope
AA 1-366, Extracellular Domain
18
16
13
10
9
8
7
6
6
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
188
50
42
3
3
Host
Rabbit
118
66
17
1
Clonality
Polyclonal
Conjugate
This FGFR4 antibody is un-conjugated
7
7
6
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Application
ELISA
145
90
51
50
31
26
13
8
7
7
4
3
2
1
1
Supplier
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Catalog No. ABIN2000537
$ 163.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2000539 ELISA Rabbit IgG AA 1-366, Extracellular Domain Log in to see Polyclonal 1
1 ABIN3182397 ELISA WB Rabbit IgG pTyr642 Log in to see Polyclonal
1 ABIN1584456 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1584455 ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN3030960 ELISA WB Rabbit Ig Fraction AA 448-482 Log in to see Polyclonal
1 ABIN1086147 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1086148 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2740889 ELISA WB Rabbit AA 448-482 Log in to see Polyclonal
1 ABIN2750027 IP ELISA WB FITC Rabbit IgG AA 520-570 Log in to see Polyclonal
1 ABIN2750031 IP ELISA WB FITC Rabbit IgG AA 530-580, phosphorylated Log in to see Polyclonal
1 ABIN2417029 IF ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1576513 ELISA WB Rabbit pTyr642 Log in to see Polyclonal
1 ABIN2750030 IP ELISA WB Rabbit IgG AA 530-580, phosphorylated Log in to see Polyclonal
1 ABIN2750026 IP ELISA WB Rabbit IgG AA 520-570 Log in to see Polyclonal
1 ABIN5507025 ELISA Rabbit IgG AA 1-366 Log in to see Polyclonal
1 ABIN1847870 ELISA WB Rabbit C-Term, pTyr642, pTyr639, pTyr640 Log in to see Polyclonal
1 ABIN2929297 ELISA IF/ICC IHC WB Rabbit AA 165-366 Log in to see Polyclonal

Similar anti-FGFR4 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 18 Antibodies
Flow Cytometry (FACS) 14 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 33 Antibodies

General

Antigen Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies
Epitope AA 1-366, Extracellular Domain
(18), (16), (13), (10), (9), (8), (7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(188), (50), (42), (3), (3)
Host Rabbit
(118), (66), (17), (1)
Clonality
Polyclonal
Conjugate This FGFR4 antibody is un-conjugated
(7), (7), (6), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application ELISA
(145), (90), (51), (50), (31), (26), (13), (8), (7), (7), (4), (3), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-FGFR4 Antibody

Target Details FGFR4 Application Details Handling References for anti-FGFR4 Antibody (ABIN2000537) Images
Specificity Mouse FGFR4
Characteristics Produced in rabbits immunized with purified, recombinant Mouse FGFR4 / FGF Receptor 4 extracellular domain (rM FGFR4, ABIN2007498 Met 1-Asp 366, NP_032037.2,. Total IgG was purified by Protein A affinity chromatography.
Purification purified by Protein A affinity chromatography
Sterility 0.2 μm filtered
Immunogen Human cell-derived rM FGFR4 extracellular domain (ABIN2007498)
Isotype IgG

Target Details FGFR4

Product Details anti-FGFR4 Antibody Application Details Handling References for anti-FGFR4 Antibody (ABIN2000537) Images back to top
Antigen
Alternative Name FGFR4 (FGFR4 Antibody Abstract)
Background Fibroblast growth factor receptor 4 (FGFR4) also known as CD334 antigen or tyrosine kinase related to fibroblast growth factor receptor, is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of FGFR4/CD334 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4/CD334 preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. FGFR4/CD334 signaling is down-regulated by receptor internalization and degradation, MMP14 promotes internalization and degradation of FGFR4/CD334. Mutations in FGFR4/CD334 lead to constitutive kinase activation or impair normal FGFR4 inactivation lead to aberrant signaling.
NCBI Accession NP_032037.2
Research Area Cancer, Growth Factors, Angiogenesis, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-FGFR4 Antibody Target Details FGFR4 Handling References for anti-FGFR4 Antibody (ABIN2000537) Images back to top
Application Notes ELISA: 0.5-1 μg/mL
This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Mouse FGFR4. The detection limit for Mouse FGFR4 is approximately 0.00975 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details References for anti-FGFR4 Antibody (ABIN2000537) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

References for anti-FGFR4 Antibody (ABIN2000537)

Product Details anti-FGFR4 Antibody Target Details FGFR4 Application Details Handling Images back to top
Background publications

Xie, Holcomb, Deuel, Dowd, Huang, Vagts, Foster, Liang, Brush, Gu, Hillan, Goddard, Gurney: "FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4." in: Cytokine, Vol. 11, Issue 10, pp. 729-35, 1999

Xie, Holcomb, Deuel, Dowd, Huang, Vagts, Foster, Liang, Brush, Gu, Hillan, Goddard, Gurney: "FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4." in: Cytokine, Vol. 11, Issue 10, pp. 729-35, 1999