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|Antigen||C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This FIGF antibody is un-conjugated Alternatives|
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-FIGF AntibodyTarget Details FIGF Application Details Handling Images
|Specificity||This antibody detects endogenous levels of VEGF-D protein. (region surrounding Ile202)|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purity||> 95 % by SDS-PAGE|
Target Details FIGFProduct Details anti-FIGF Antibody Application Details Handling Images back to top
|Alternative Name||VEGFD (Figf Antibody Abstract)|
|Background||The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). Several forms of VEGF have been identified, including VEGF, VEGF-B, VEGFC and VEGF-D (also designated FIGF). Characteristic of VEGF proteins, the central region of VEGF-D contains eight cysteine residues. These residues are essential for homodimerization. VEGFD may play a role in tumor progression, as it is induced by c-Fos, which is required for conversion of early stage tumors to malignant tumors. It has been observed that overexpression of VEGF-D induces morphological changes in fibroblasts.Synonyms: FIGF, VEGF-D, Vascular endothelial growth factor D, c-Fos-induced growth factor|
|Molecular Weight||approx. 40 kDa|
|Research Area||Cancer, Angiogenesis, Growth Factors|
Application DetailsProduct Details anti-FIGF Antibody Target Details FIGF Handling Images back to top
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FIGF Antibody Target Details FIGF Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-FIGF Antibody Target Details FIGF Application Details Handling back to top