Browse our anti-FLT1 (FLT1) Antibodies

Full name:
anti-Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) Antibodies (FLT1)
On www.antibodies-online.com are 464 Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Antibodies from 38 different suppliers available. Additionally we are shipping FLT1 Proteins (71) and FLT1 Kits (63) and many more products for this protein. A total of 619 FLT1 products are currently listed.
Synonyms:
AI323757, FLT, FLT-1, FLT1, flt1b, sFlt1, VEGFR-1, VEGFR1

All available anti-FLT1 Antibodies

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Top referenced anti-FLT1 Antibodies

  1. Human Monoclonal FLT1 Primary Antibody for FACS - ABIN4897100 : Karrar, Broomé, Uzunel, Qureshi, Sumitran-Holgersson: Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. in Gut 2007 (PubMed)
    Show all 16 references for 4897100

  2. Human Monoclonal FLT1 Primary Antibody for FACS - ABIN4897099 : de Groot, Piao, Tran, Gilbert, Wu, Liu, Bekele, Cloughesy, Mehta, Robins, Lassman, DeAngelis, Camphausen, Chen, Yung, Prados, Wen, Heymach: Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept. in Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)
    Show all 5 references for 4897099

  3. Human Monoclonal FLT1 Primary Antibody for IHC (fro), IF - ABIN1109475 : Imbert, Rosnet, Marchetto, Ollendorff, Birnbaum, Pébusque: Characterization of a yeast artificial chromosome from human chromosome band 13q12 containing the FLT1 and FLT3 receptor-type tyrosine kinase genes. in Cytogenetics and cell genetics 1994 (PubMed)
    Show all 2 references for 1109475

  4. Mouse (Murine) Monoclonal FLT1 Primary Antibody for FACS - ABIN4897107 : Reddy, Zhou, Schadler, Jia, Kleinerman: Bone marrow subsets differentiate into endothelial cells and pericytes contributing to Ewing's tumor vessels. in Molecular cancer research : MCR 2008 (PubMed)
    Show all 2 references for 4897107

  5. Mouse (Murine) Monoclonal FLT1 Primary Antibody for FACS - ABIN4897105 : Fang, Wei, Pentinmikko, Leinonen, Salven: Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. in PLoS biology 2012 (PubMed)
    Show all 2 references for 4897105

  6. Human Polyclonal FLT1 Primary Antibody for IHC (p), WB - ABIN115391 : Ahmed, Li, Dunk, Whittle, Rushton, Rollason: Colocalisation of vascular endothelial growth factor and its Flt-1 receptor in human placenta. in Growth factors (Chur, Switzerland) 1996 (PubMed)
    Show all 2 references for 115391

  7. Human Polyclonal FLT1 Primary Antibody for IHC, ELISA - ABIN1532085 : Shibuya, Yamaguchi, Yamane, Ikeda, Tojo, Matsushime, Sato: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. in Oncogene 1990 (PubMed)

  8. Human Polyclonal FLT1 Primary Antibody for EIA, FACS - ABIN955511 : Wong, Buckman, Clemons, Verma, Dent, Trudeau, Roche, Ebos, Kerbel, Deboer, Sutherland, Emmenegger, Slingerland, Gardner, Pritchard: Phase I/II trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growt in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 (PubMed)

More Antibodies against FLT1 Interaction Partners

Mouse (Murine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. First-in-class selective PET tracers for imaging VEGFR-1 and VEGFR-2 (show KDR Antibodies) were constructed and successfully validated in an orthotopic murine tumor model.

  2. these results suggest that VEGFR1 signaling plays a role in regulating the balance between macrophage phenotypes in streptozotocin -induced diabetic wounds, prevents impaired diabetic wound healing, and promotes angiogenesis/lymphangiogenesis.

  3. These data therefore support a tightly controlled, paracrine signaling mechanism of VEGF-B (show VEGFB Antibodies) to VEGFR1.

  4. Flt1/VEGF-A (show VEGFA Antibodies) signalling has stage-specific effects on vascular morphogenesis.

  5. IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors

  6. the VEGFR-1 tyrosine kinase (show TYRO3 Antibodies) signaling has an effect on angiogenesis.

  7. data suggest that sFlt-1 may have a therapeutic effect on AS, resulting from suppression of VEGF signaling-mediated recruitment of circulating monocytes/macrophages

  8. that Flt-1 plays a critical role in cardiac hypertrophy induced by pressure overload via the activation of AKT (show AKT1 Antibodies)

  9. Flt-1 appears to play a role in oxidative stress, which promotes apoptosis of trophoblasts

  10. This article reviews the current evidence on the clinical utility of the sFlt-1/PlGF (show PGF Antibodies) ratio at different points in pregnancy and, accordingly, make a proposal for its clinical implementation. [review]

Human Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. FLT-1 rs7324510 C/A variant may be a new genetic risk factor for severity of rheumatoid arthritis. Examined factor highly predispose to more severe disease activity as well as higher sFLT-1 levels in rheumatoid arthritis.

  2. Molecular dynamics simulations of VEGFR-1 Wt and (p.Cys1110Ser) variant revealed exposure of the activation domain increasing the probability of phosphorylation events: a condition frequently reported in cancers.

  3. The normalized methylation values for the VEGFR1, VEGFR2 (show KDR Antibodies) and VEGFR3 (show FLT4 Antibodies) promoters tended to be higher in the tumour cell lines than in normal tonsil samples, whereas amounts of VEGFR1, VEGFR2 (show KDR Antibodies) and VEGFR3 (show FLT4 Antibodies) messenger RNA were significantly higher

  4. Both the TNF-alpha (show TNF Antibodies)/IL-10 (show IL10 Antibodies) and sFlt-1/PlGF (show PGF Antibodies) ratios were higher in placental homogenate of early-onset Preeclampsia (PE) than late-onset PE and control groups. The more severe lesions and the imbalance between TNF-alpha (show TNF Antibodies)/IL-10 (show IL10 Antibodies) and PlGF (show PGF Antibodies)/sFlt-1 in placentas from early-onset PE allows differentiation of early and late-onset PE and suggests higher placental impairment in early-onset PE

  5. this study shows that Fli-1 (show FLI1 Antibodies) plays a major role in the regulation of granulocyte colony stimulating factor (show CSF3 Antibodies)

  6. Patients with post-peripartum cardiomyopathy have significantly higher plasma sFlt1 concentration with a trend of somewhat higher levels of VEGF (show VEGFA Antibodies) and significantly decreased VEGF (show VEGFA Antibodies)/sFlt1 ratio compared to controls.

  7. soluble fms-like tyrosine kinase-1 inhibits cell proliferation, migration, and invasion of colorectal cancer SW480 cells through suppression of vascular mimicry formation, which provides a good basis for the development of new drugs for the treatment of colorectal cancer by targeting both angiogenesis and vascular mimicry formation.

  8. a significant association between the expanded disability status scale and sVEGFR1 (beta=0.007; p<0.001). Our findings revealed that circulatory membranous as well as soluble expression of VEGFR1 increases during angiogenic and inflammatory phenomena of MS.

  9. Data suggest that the associations among angiopoietin-2 (show ANGPT2 Antibodies), sFlt-1, coagulation abnormalities and severe course of acute pancreatitis (AP) might be mediated by other bioactive compounds.

  10. The preeclampsia group had higher soluble fms-like tyrosine kinase-1 from >/=28 weeks compared to controls.

Cow (Bovine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. These results suggest that non-dominant follicles maintain a greater concentration of the mRNA expression of both membrane and soluble VEGF receptors; but follicular dominance is related to a reduction in the mRNA expression of sVEGFR1 and sVEGFR2.

  2. VEGFR-1 negatively regulates primary bovine retinal pericytes survival, and its blockade protects the blood-brain barrier integrity.

  3. gamma-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1

  4. VEGFR1 mRNA expression was lower at estrus and at the early I and early II luteal stages than at the other stages, whereas VEGFR1 protein expression did not change significantly throughout the estrous cycle (P<0.05)

  5. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF (show FGF2 Antibodies) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

  6. inhibition of VEGFR-1 results in decrease in number of capillary connections indicating VEGFR-1 ligands promote branching angiogenesis.

  7. TGF-beta1 (show TGFB1 Antibodies) induction of VEGFR-1 in endothelial cells explains pericyte protection of vessels and the selective vulnerability of neonatal vessels to oxygen(VEGFR-1)

  8. the activation of VEGFR-1 and VEGFR-2 (show KDR Antibodies) heterodimer (VEGFR-1/R-2) is essential for PGI(2 (show PTGIR Antibodies)) synthesis mediated by VEGF-A (show VEGFA Antibodies)(165) and VEGF-A (show VEGFA Antibodies)(121), which cannot be reproduced by the parallel activation of VEGFR-1 and VEGFR-2 (show KDR Antibodies) homodimers with corresponding agonists

  9. PEDF (show SERPINF1 Antibodies) and VEGFR-1 have roles in the negative regulation of angiogenesis

Pig (Porcine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. we analyzed the expression and cellular distribution of Flt-1(VEGFR-1) and Flk-1 (KDR/VEGFR-2 (show KDR Antibodies))in newborn piglet brain

  2. data shows that members of the VEGF (show VEGFA Antibodies)-VEGFR (show KDR Antibodies) system are temporally and spatially well localized for playing key roles during umbilical cord formation and its intensive growth observed after day 75 of pregnancy

  3. The VEGFR1 was stably expressed during the whole lifespan of mesonephric glomeruli, and VEGFR1 is important for the maintenance of endothelial fenestrations.

  4. increased placental expression of the VEGF receptor system is associated with increased placental vascular density observed with the advancement of gestation in the pig.

  5. EGFR (show EGFR Antibodies), VEGFR (show KDR Antibodies) and FGFR (show FGFR2 Antibodies) are expressed in porcine oviduct and endometrium during the time of implantation [review]

  6. VEGF ligand-receptor system may play an important role in the development and maintenance of the corpus luteum in pigs.

  7. VEGF (show VEGFA Antibodies)/Flk-1 (show KDR Antibodies)/Flt-1 system is activated during myocardial ischemia reperfusion injury.

  8. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (show VEGFA Antibodies), pro-MMP-9 (show MMP9 Antibodies), MMP-2 (show MMP2 Antibodies), VEGFR-1, VEGFR-2 (show KDR Antibodies), and TIMP-1 (show TIMP1 Antibodies), which may contribute to the development of venous stenosis.

  9. in experimental intervertebral disc degeneration, VEGF receptors were expressed in the damaged disc and paradiscal tissues

Zebrafish Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. Flt1-tyrosine kinase (TK) activity contributed significantly in endothelial cells survival and vascular development during embryo angiogenesis in zebrafish by engaging PI3K/Akt (show AKT1 Antibodies) pathway.

  2. Elevated Notch (show NOTCH1 Antibodies) signaling downstream of perturbed VEGF (show VEGFA Antibodies) signaling contributes to aberrant flt-1(-/-) blood vessel formation.

  3. Data indicate that the increase in FLT1/sFLT1 protein levels upon miR-10 (show LILRB2 Antibodies) knockdown inhibited the angiogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor receptor 2 (show KDR Antibodies) signaling.

FLT1 Antigen Profile

Antigen Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Alternative names and synonyms associated with FLT1

  • fms-related tyrosine kinase 1 (FLT1) antibody
  • vascular endothelial growth factor receptor 1 (CpipJ_CPIJ012087) antibody
  • FMS-like tyrosine kinase 1 (Flt1) antibody
  • FMS-related tyrosine kinase 1 (Flt1) antibody
  • fms-related tyrosine kinase 1 (Flt1) antibody
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1) antibody
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (flt1) antibody
  • vascular endothelial growth factor receptor-1 (FLT-1) antibody
  • AI323757 antibody
  • FLT antibody
  • FLT-1 antibody
  • FLT1 antibody
  • flt1b antibody
  • sFlt1 antibody
  • VEGFR-1 antibody
  • VEGFR1 antibody

Protein level used designations for FLT1

fms-related tyrosine kinase 1 , vascular endothelial growth factor receptor 1 , embryonic receptor kinase 2 , tyrosine-protein kinase receptor FLT , vascular endothelial growth factor receptor-1 , vascular permeability factor receptor , fms-like tyrosine kinase 1 , fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) , tyrosine-protein kinase FRT , FLT-1 , FMS-like tyrosine kinase 1 , Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) , VEGF-receptor , flt-receptor , vascular endothelial growth factor 1 , vascular endothelial growth factor/vascular permeability factor receptor , ascular endothelial growth factor/vascular permeability factor receptor , VEGFR-1 , flt-1 type VEGF receptor , receptor tyrosine kinase Flt1b , soluble fms-like tyrosine kinase 1

GENE ID SPECIES
443088 Ovis aries
6044537 Culex quinquefasciatus
14254 Mus musculus
2321 Homo sapiens
54251 Rattus norvegicus
100732326 Cavia porcellus
503620 Bos taurus
403727 Canis lupus familiaris
374100 Gallus gallus
396763 Sus scrofa
544667 Danio rerio
443182 Ovis aries
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