anti-Human FLT3 antibody for ELISA

Recommended FLT3 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
  • FLT3
  • B230315G04
  • CD135
  • Flk-2
  • Flk2
  • Flt-3
  • Ly72
  • wmfl
  • FLK-2
  • FLK2
  • STK1
  • fms-related tyrosine kinase 3
  • FMS-like tyrosine kinase 3
  • FLT3
  • Flt3
Epitope
AA 930-991
36
32
29
22
22
14
14
12
12
10
8
7
4
4
4
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
308
159
45
4
1
1
1
1
1
1
Host
Mouse
262
72
26
4
1
Clonality
Monoclonal
Conjugate
This FLT3 antibody is un-conjugated
21
20
16
11
10
6
6
6
6
6
6
4
4
4
4
4
4
3
2
2
2
2
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
177
122
97
54
54
48
22
15
11
5
4
3
2
2
2
1
1
1
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Catalog No. ABIN1724846
$ 430.10
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.499185 ABIN947874 IF ELISA Mouse IgG2a kappa AA 91-190, partial Log in to see 3H1
12.499185 ABIN1845923 IHC ELISA WB Mouse IgG1 AA 930-991 Log in to see
1 ABIN1532045 IHC ELISA WB Rabbit IgG pTyr969 Log in to see Polyclonal 2
1 ABIN1531319 ELISA WB Rabbit IgG pTyr599 Log in to see Polyclonal 2
1 ABIN1532044 ELISA WB Rabbit IgG pTyr842 Log in to see Polyclonal 2
1 ABIN1532338 ELISA WB Rabbit IgG Log in to see Polyclonal 2
1 ABIN1077372 IF ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1996829 IP ELISA WB Rabbit IgG AA 1-200 Log in to see Polyclonal 1
1 ABIN1996825 ELISA Mouse IgG1 AA 1-541 Log in to see 4G7E6B7 1
1 ABIN3184641 ELISA WB Rabbit IgG Ser387 Log in to see Polyclonal
1 ABIN3182315 ELISA WB Rabbit IgG pTyr842 Log in to see Polyclonal
1 ABIN2888661 ELISA WB Rabbit IgG AA 565-614 Log in to see Polyclonal
1 ABIN3181448 ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1996827 ELISA Rabbit IgG AA 1-200 Log in to see Polyclonal 1
1 ABIN213538 IHC (p) ELISA Rabbit Internal Region Log in to see Polyclonal
1 ABIN2469458 IHC ELISA Rabbit Internal Region Log in to see Polyclonal
1 ABIN4880723 ELISA IHC WB Mouse IgG1 AA 930-991 Log in to see 7B7C3
1 ABIN1964020 ELISA WB APC Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN1964021 FACS ELISA APC Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN1961641 FACS ELISA Alkaline Phosphatase (AP) Rabbit IgG N-Term Log in to see Polyclonal

General

Antigen Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
Epitope AA 930-991
(36), (32), (29), (22), (22), (14), (14), (12), (12), (10), (8), (7), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(308), (159), (45), (4), (1), (1), (1), (1), (1), (1)
Host Mouse
(262), (72), (26), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT3 antibody is un-conjugated
(21), (20), (16), (11), (10), (6), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(177), (122), (97), (54), (54), (48), (22), (15), (11), (5), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-FLT3 Antibody

Target Details FLT3 Application Details Handling References for anti-FLT3 antibody (ABIN1724846) Images
Purification Purified
Immunogen Purified recombinant fragment of human FLT3 (AA 930-991) expressed in E. Coli.
Clone 7B7C3
Isotype IgG1

Target Details FLT3

Product Details anti-FLT3 Antibody Application Details Handling References for anti-FLT3 antibody (ABIN1724846) Images back to top
Antigen
Alternative Name FLT3 (FLT3 Antibody Abstract)
Background This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. ,
Molecular Weight 130 kDa
Gene ID 2322
HGNC 2322
Pathways RTK Signaling

Application Details

Product Details anti-FLT3 Antibody Target Details FLT3 Handling References for anti-FLT3 antibody (ABIN1724846) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details References for anti-FLT3 antibody (ABIN1724846) Images back to top
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-FLT3 antibody (ABIN1724846)

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling Images back to top
Product cited in:

Pereira de Sousa, Berthault, Granato, Dias, Ramond, Kee, Cumano, Vieira: "Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 8, pp. 3822-30, 2012

How, Sykes, Gupta, Yee, Schimmer, Schuh, Minden, Kamel-Reid, Brandwein: "Influence of FLT3-internal tandem duplication allele burden and white blood cell count on the outcome in patients with intermediate-risk karyotype acute myeloid leukemia." in: Cancer, Vol. 118, Issue 24, pp. 6110-7, 2012

Images

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling References for anti-FLT3 antibody (ABIN1724846) back to top
Supplier Images
ELISA image for anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody (ABIN1724846) anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
Western Blotting (WB) image for anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody (ABIN1724846) anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody (Image 2)