anti-Human FLT3 antibody for Flow Cytometry

Recommended FLT3 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
  • FLT3
  • B230315G04
  • CD135
  • Flk-2
  • Flk2
  • Flt-3
  • Ly72
  • wmfl
  • FLK-2
  • FLK2
  • STK1
  • fms-related tyrosine kinase 3
  • FMS-like tyrosine kinase 3
  • FLT3
  • Flt3
Reactivity
Human
324
174
47
4
1
1
1
1
1
1
Host
Mouse
265
84
37
8
1
Clonality
Monoclonal
Conjugate
This FLT3 antibody is conjugated to Biotin
23
22
16
13
10
8
8
8
8
8
6
4
4
4
4
4
4
4
4
3
2
2
2
1
Application
Flow Cytometry (FACS)
183
124
123
54
54
49
22
15
12
10
4
3
2
2
2
1
1
1
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Catalog No. ABIN2660938
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.996978 ABIN2658477 FACS APC Mouse IgG1 kappa Log in to see BV10A4H2 4
13.996978 ABIN1996824 FACS FITC Mouse IgG1 AA 1-541 Log in to see 02
13.996978 ABIN2663011 FACS PE Mouse IgG1 kappa Log in to see BV10A4H2 4
13.996978 ABIN2658914 FACS PE-Cy5 Mouse IgG1 kappa Log in to see BV10A4H2 4
13.996978 ABIN2659088 FACS PE-Cy7 Mouse IgG1 kappa Log in to see BV10A4H2 4
13.996978 ABIN2664204 FACS Mouse IgG1 kappa Log in to see BV10A4H2 4
13.996978 ABIN2213921 FACS APC Mouse IgG1 AA 1-541 Log in to see 02
13.996978 ABIN4897091 FACS Allophycocyanin Mouse IgG1 AA 27-541 Log in to see 66903
13.996978 ABIN4897092 FACS Fluorescein Mouse IgG1 AA 27-541 Log in to see 66903
13.996978 ABIN4897094 FACS PE Mouse IgG1 AA 27-541 Log in to see 66903
13.996978 ABIN4897093 FACS Alexa Fluor 700 Mouse IgG1 AA 27-541 Log in to see 66903
13.996978 ABIN2682004 FACS Mouse IgG1 AA 1-541 Log in to see 02
13.996978 ABIN3030975 FACS IHC ELISA WB Rabbit Ig Fraction AA 33-64 Log in to see Polyclonal
1 ABIN391981 FACS IHC (p) WB Rabbit Ig AA 33-64, N-Term Log in to see Polyclonal 4
1 ABIN614773 FACS IP Mouse IgG1 Log in to see BV10A4 5
1 ABIN614774 FACS PE Mouse IgG1 Log in to see BV10A4 5
1 ABIN4900035 CyTOF FACS Mouse IgG1 AA 27-541 Log in to see 66903 1
1 ABIN4900036 CyTOF FACS Mouse IgG1 AA 27-541 Log in to see 66903 1
1 ABIN4900037 CyTOF FACS WB Goat IgG AA 27-541 Log in to see Polyclonal 2
1 ABIN489931 FACS IP PE Mouse IgG1 Log in to see BV10A4 5

General

Antigen Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
Reactivity Human
(324), (174), (47), (4), (1), (1), (1), (1), (1), (1)
Host Mouse
(265), (84), (37), (8), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT3 antibody is conjugated to Biotin
(23), (22), (16), (13), (10), (8), (8), (8), (8), (8), (6), (4), (4), (4), (4), (4), (4), (4), (4), (3), (2), (2), (2), (1)
Application Flow Cytometry (FACS)
(183), (124), (123), (54), (54), (49), (22), (15), (12), (10), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-FLT3 Antibody

Target Details FLT3 Application Details Handling References for anti-FLT3 antibody (ABIN2660938) Images
Purification The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Clone BV10A4H2
Isotype IgG1 kappa

Target Details FLT3

Product Details anti-FLT3 Antibody Application Details Handling References for anti-FLT3 antibody (ABIN2660938) Images back to top
Antigen
Alternative Name CD135 (FLT3 Antibody Abstract)
Background CD135 is a 130-160 kD type III tyrosine kinase receptor expressed on CD34+ hematopoietic stem cells, myelomonocytic progenitors, primitive B cell progenitors, and thymocytes. CD135 is also expressed on malignant hematopoietic cells including AML, ALL and CML-BC. CD135, also known as FMS-like tyrosine kinase-3, FLT3, STK-1, and Flk-2, is a growth factor receptor that binds the FLT3 ligand to promote the growth and differentiation of primitive hematopoietic cells. The intracytoplasmic domain of CD135 is modified by phosphorylation and has been shown to interact with Grb2, SOCS1, VAV1, and Shc.
Research Area CD Antigens
Pathways RTK Signaling

Application Details

Product Details anti-FLT3 Antibody Target Details FLT3 Handling References for anti-FLT3 antibody (ABIN2660938) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details References for anti-FLT3 antibody (ABIN2660938) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-FLT3 antibody (ABIN2660938)

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling Images back to top
Background publications

Bertho, Chapel, Loilleux, Frick, Aigueperse, Gorin, Gourmelon: "CD135 (Flk2/Flt3) expression by human thymocytes delineates a possible role of FLT3-ligand in T-cell precursor proliferation and differentiation." in: Scandinavian journal of immunology, Vol. 52, Issue 1, pp. 53-61, 2000

Rappold, Ziegler, Köhler, Marchetto, Rosnet, Birnbaum, Simmons, Zannettino, Hill, Neu, Knapp, Alitalo, Alitalo, Ullrich, Kanz, Bühring: "Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase." in: Blood, Vol. 90, Issue 1, pp. 111-25, 1997

Rosnet, Bühring, Marchetto, Rappold, Lavagna, Sainty, Arnoulet, Chabannon, Kanz, Hannum, Birnbaum: "Human FLT3/FLK2 receptor tyrosine kinase is expressed at the surface of normal and malignant hematopoietic cells." in: Leukemia, Vol. 10, Issue 2, pp. 238-48, 1996

Rosnet, Bühring, deLapeyrière, Beslu, Lavagna, Marchetto, Rappold, Drexler, Birg, Rottapel, Hannum, Dubreuil, Birnbaum: "Expression and signal transduction of the FLT3 tyrosine kinase receptor." in: Acta haematologica, Vol. 95, Issue 3-4, pp. 218-23, 1996

Images

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling References for anti-FLT3 antibody (ABIN2660938) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (Biotin) (ABIN2660938) anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (Biotin)